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The map label for this gene is yfnA [H]

Identifier: 82752183

GI number: 82752183

Start: 2612647

End: 2614095

Strand: Direct

Name: yfnA [H]

Synonym: SAB2476

Alternate gene names: 82752183

Gene position: 2612647-2614095 (Clockwise)

Preceding gene: 82752180

Following gene: 82752184

Centisome position: 95.26

GC content: 37.47

Gene sequence:

>1449_bases
ATGGGAAGTTTTTTCAATAAAATAGCACGAAAAGAGGATCCGGCTATCTATCAAAATAAAGATGGTCATTTAAAGCGTAC
ACTTCGGGTGCGTGATTTCTTAGCTTTAGGTGTAGGAACAATTGTATCGACATCTATCTTTACGCTACCTGGCATTGTTG
CTGCAGAACATGCAGGACCGGCCGTTGCGTTATCATTCTTACTCGCTGCTATTGTTGCTGGTTTAGTTGCATTTACTTAT
GCAGAAATGGCTGCCGCTATGCCATTTGCAGGTTCAGCCTATTCTTGGGTCAATGTATTATTTGGTGAATTTTTTGGATG
GGTTGCCGGTTGGGCTCTATTAGCTGAATATTTTATCGCCGTAGCCTTTGTTGCATCAGGATTCTCAGCGAATTTACGCG
GACTTGTGAAACCAATTGGCATCGAATTACCTGCAGCATTATCAAATCCATTTGGTACGAATGGCGGTTTTATCGATATT
ATTGCTGCTATCGTTATTTTATTAACTGCATTATTACTATCACGTGGTATGTCAGAAGCAGCACGTATGGAAAACATTTT
AGTTATTTTAAAAGTATTAGCTATTATTTTATTTGTAATCGTAGGTTTAACAGCAATAAATGTTAGTAACTATGTGCCAT
TTATTCCAGAACACAAAGTAACTGCTACAGGCGACTTTGGTGGATGGCAAGGCATATATGCTGGTGTTTCAATGATTTTC
TTAGCGTATATCGGTTTCGATTCTATCGCAGCAAACTCAGCAGAAGCACTTGACCCTCAAAAGACAATGCCTAGAGGTAT
TCTTGGTTCTTTAAGTGTTGCTATCGTATTATTTATTGCTGTAGCACTTGTGTTAGTTGGTATGTTCCATTACTCACAAT
ACGCAAACAATGCTGAACCTGTTGGTTGGGCTTTACGTCAAAGTGGTCATGGTGTTGTAGCAGCTATTGTTCAAGCTATC
TCTGTTATCGGTATGTTTACAGCATTAATTGGTATGATGTTAGCAGGCTCACGTTTACTTTATTCATTTGGACGTGACGG
CTTATTACCTTCATGGTTAAGCCACTTAAACGACAAACATTTACCTAATCGCGCACTAGTTATACTTACTATTATTGGTG
TTTTAATTGGTTCTATGTTCCCATTCGCATTTTTAGCACAATTAATTTCAGCAGGTACACTTGTTGCATTTATGTTCGTT
TCATTAGCAATGTATCGTTTGAGAAAGCGTGAAGGTAAAGATCTACCAATTCCTGCATTTAAATTACCTTTATATCCTGT
GTTACCAGCAGTTACATTTGTTTTAGTATTGCTAGTATTCTGGGGATTAGGATTCGAAGCGAAATTATACACTTTAATTT
GGTTTATTGTTGGTATCATTCTATATTTAAGTTATGGACTTAGACATTCTAAGAAAAATGACGTAGCTGAATACCACCCA
CCAAAATAA

Upstream 100 bases:

>100_bases
TTTCAGAATTTTTAGACAAAATATTGATTATTTGTGCTATGATATAACATATTAAAAATCACCGTATAGAATTGTTTATG
AATGTTTGGGAGGAAAGTTT

Downstream 100 bases:

>100_bases
AAATCAAAAAAATCATTTCCCATCTGATTAACATCCAGATGCGGAAATGATTTTTTATTTTATATTAAGAGAATCGCTAT
TACCAACCTTGTCCAGATAT

Product: cationic amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MGSFFNKIARKEDPAIYQNKDGHLKRTLRVRDFLALGVGTIVSTSIFTLPGIVAAEHAGPAVALSFLLAAIVAGLVAFTY
AEMAAAMPFAGSAYSWVNVLFGEFFGWVAGWALLAEYFIAVAFVASGFSANLRGLVKPIGIELPAALSNPFGTNGGFIDI
IAAIVILLTALLLSRGMSEAARMENILVILKVLAIILFVIVGLTAINVSNYVPFIPEHKVTATGDFGGWQGIYAGVSMIF
LAYIGFDSIAANSAEALDPQKTMPRGILGSLSVAIVLFIAVALVLVGMFHYSQYANNAEPVGWALRQSGHGVVAAIVQAI
SVIGMFTALIGMMLAGSRLLYSFGRDGLLPSWLSHLNDKHLPNRALVILTIIGVLIGSMFPFAFLAQLISAGTLVAFMFV
SLAMYRLRKREGKDLPIPAFKLPLYPVLPAVTFVLVLLVFWGLGFEAKLYTLIWFIVGIILYLSYGLRHSKKNDVAEYHP
PK

Sequences:

>Translated_482_residues
MGSFFNKIARKEDPAIYQNKDGHLKRTLRVRDFLALGVGTIVSTSIFTLPGIVAAEHAGPAVALSFLLAAIVAGLVAFTY
AEMAAAMPFAGSAYSWVNVLFGEFFGWVAGWALLAEYFIAVAFVASGFSANLRGLVKPIGIELPAALSNPFGTNGGFIDI
IAAIVILLTALLLSRGMSEAARMENILVILKVLAIILFVIVGLTAINVSNYVPFIPEHKVTATGDFGGWQGIYAGVSMIF
LAYIGFDSIAANSAEALDPQKTMPRGILGSLSVAIVLFIAVALVLVGMFHYSQYANNAEPVGWALRQSGHGVVAAIVQAI
SVIGMFTALIGMMLAGSRLLYSFGRDGLLPSWLSHLNDKHLPNRALVILTIIGVLIGSMFPFAFLAQLISAGTLVAFMFV
SLAMYRLRKREGKDLPIPAFKLPLYPVLPAVTFVLVLLVFWGLGFEAKLYTLIWFIVGIILYLSYGLRHSKKNDVAEYHP
PK
>Mature_481_residues
GSFFNKIARKEDPAIYQNKDGHLKRTLRVRDFLALGVGTIVSTSIFTLPGIVAAEHAGPAVALSFLLAAIVAGLVAFTYA
EMAAAMPFAGSAYSWVNVLFGEFFGWVAGWALLAEYFIAVAFVASGFSANLRGLVKPIGIELPAALSNPFGTNGGFIDII
AAIVILLTALLLSRGMSEAARMENILVILKVLAIILFVIVGLTAINVSNYVPFIPEHKVTATGDFGGWQGIYAGVSMIFL
AYIGFDSIAANSAEALDPQKTMPRGILGSLSVAIVLFIAVALVLVGMFHYSQYANNAEPVGWALRQSGHGVVAAIVQAIS
VIGMFTALIGMMLAGSRLLYSFGRDGLLPSWLSHLNDKHLPNRALVILTIIGVLIGSMFPFAFLAQLISAGTLVAFMFVS
LAMYRLRKREGKDLPIPAFKLPLYPVLPAVTFVLVLLVFWGLGFEAKLYTLIWFIVGIILYLSYGLRHSKKNDVAEYHPP
K

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258645169, Length=435, Percent_Identity=29.6551724137931, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI258614005, Length=436, Percent_Identity=29.3577981651376, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI258614003, Length=436, Percent_Identity=29.3577981651376, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI4507047, Length=421, Percent_Identity=30.4038004750594, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI181337167, Length=406, Percent_Identity=29.5566502463054, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI114326544, Length=422, Percent_Identity=30.3317535545024, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI114326550, Length=422, Percent_Identity=30.3317535545024, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI110347453, Length=418, Percent_Identity=29.9043062200957, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI33286428, Length=434, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI87081708, Length=480, Percent_Identity=22.9166666666667, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1786789, Length=437, Percent_Identity=25.4004576659039, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788480, Length=451, Percent_Identity=24.1685144124169, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081915, Length=424, Percent_Identity=23.8207547169811, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082250, Length=379, Percent_Identity=26.6490765171504, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786302, Length=421, Percent_Identity=22.5653206650831, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790653, Length=468, Percent_Identity=23.0769230769231, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789017, Length=451, Percent_Identity=23.2815964523282, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994972, Length=484, Percent_Identity=22.3140495867769, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081869, Length=468, Percent_Identity=24.1452991452991, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786602, Length=472, Percent_Identity=20.3389830508475, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082023, Length=473, Percent_Identity=25.5813953488372, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786694, Length=470, Percent_Identity=24.6808510638298, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI2367353, Length=451, Percent_Identity=21.5077605321508, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=419, Percent_Identity=30.7875894988067, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17532491, Length=448, Percent_Identity=29.6875, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17533459, Length=399, Percent_Identity=29.3233082706767, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321053, Length=486, Percent_Identity=22.8395061728395, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=478, Percent_Identity=23.6401673640167, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24668806, Length=433, Percent_Identity=30.715935334873, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI21356285, Length=433, Percent_Identity=30.715935334873, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24668802, Length=433, Percent_Identity=30.715935334873, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI221512776, Length=422, Percent_Identity=31.042654028436, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24666159, Length=422, Percent_Identity=31.042654028436, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24667468, Length=394, Percent_Identity=31.4720812182741, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI161077963, Length=421, Percent_Identity=29.6912114014252, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI281366235, Length=409, Percent_Identity=29.0953545232274, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI116007820, Length=409, Percent_Identity=29.0953545232274, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI116007818, Length=409, Percent_Identity=29.0953545232274, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI85725152, Length=409, Percent_Identity=29.0953545232274, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI21357367, Length=426, Percent_Identity=22.7699530516432, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI45550968, Length=432, Percent_Identity=22.6851851851852, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19921172, Length=432, Percent_Identity=22.6851851851852, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51880; Mature: 51749

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSFFNKIARKEDPAIYQNKDGHLKRTLRVRDFLALGVGTIVSTSIFTLPGIVAAEHAGP
CCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCH
AVALSFLLAAIVAGLVAFTYAEMAAAMPFAGSAYSWVNVLFGEFFGWVAGWALLAEYFIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAFVASGFSANLRGLVKPIGIELPAALSNPFGTNGGFIDIIAAIVILLTALLLSRGMSEA
HHHHHHCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
ARMENILVILKVLAIILFVIVGLTAINVSNYVPFIPEHKVTATGDFGGWQGIYAGVSMIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
LAYIGFDSIAANSAEALDPQKTMPRGILGSLSVAIVLFIAVALVLVGMFHYSQYANNAEP
HHHHHHHHHHCCCHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGWALRQSGHGVVAAIVQAISVIGMFTALIGMMLAGSRLLYSFGRDGLLPSWLSHLNDKH
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
LPNRALVILTIIGVLIGSMFPFAFLAQLISAGTLVAFMFVSLAMYRLRKREGKDLPIPAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
KLPLYPVLPAVTFVLVLLVFWGLGFEAKLYTLIWFIVGIILYLSYGLRHSKKNDVAEYHP
HCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PK
CC
>Mature Secondary Structure 
GSFFNKIARKEDPAIYQNKDGHLKRTLRVRDFLALGVGTIVSTSIFTLPGIVAAEHAGP
CHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCH
AVALSFLLAAIVAGLVAFTYAEMAAAMPFAGSAYSWVNVLFGEFFGWVAGWALLAEYFIA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAFVASGFSANLRGLVKPIGIELPAALSNPFGTNGGFIDIIAAIVILLTALLLSRGMSEA
HHHHHHCCCHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
ARMENILVILKVLAIILFVIVGLTAINVSNYVPFIPEHKVTATGDFGGWQGIYAGVSMIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
LAYIGFDSIAANSAEALDPQKTMPRGILGSLSVAIVLFIAVALVLVGMFHYSQYANNAEP
HHHHHHHHHHCCCHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGWALRQSGHGVVAAIVQAISVIGMFTALIGMMLAGSRLLYSFGRDGLLPSWLSHLNDKH
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCC
LPNRALVILTIIGVLIGSMFPFAFLAQLISAGTLVAFMFVSLAMYRLRKREGKDLPIPAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
KLPLYPVLPAVTFVLVLLVFWGLGFEAKLYTLIWFIVGIILYLSYGLRHSKKNDVAEYHP
HCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]