Click here to switch to the map view.

The map label for this gene is mtnE [H]

Identifier: 82752141

GI number: 82752141

Start: 2573866

End: 2575020

Strand: Reverse

Name: mtnE [H]

Synonym: SAB2433c

Alternate gene names: 82752141

Gene position: 2575020-2573866 (Counterclockwise)

Preceding gene: 82752142

Following gene: 82752140

Centisome position: 93.89

GC content: 36.19

Gene sequence:

>1155_bases
ATGATCTCTAACAAATTAGCAAATATCCCTGATAGTTATTTCGGGAAAACGATGGGACGTAAAATCGAACATGGACCATT
GCCATTAATTAATATGGCAGTTGGAATCCCTGATGGGCCCACGCCACAAGGTATTATTGATCATTTTCAAAAAGCACTAA
CTATTCCTGAAAATCAAAAATATGGTGCTTTTCATGGTAAAGAGATGTTCAAGCAAGCCATTGTAGATTTTTATCAAAGA
CAATATGATGTGACGTTAGATAAAGAAGATGAAGTATGTATTTTATATGGTACAAAAAATGGATTAGTGGCAGTACCAAC
ATGTGTTATCAATCCAGGAGACTATGTATTACTACCTGACCCAGGCTACACTGATTATTTAGCAGGTGTACTTTTAGCTG
ATGGCAAGCCTGTTCCGCTTAATTTAGAACCGCCGCATTATTTGCCAGATTGGTCCAAAGTTGATTCACAAATAAAAGAT
AAAACAAAACTCATTTATTTAACGTATCCAAATAATCCAACTGGATCGACAGCTACGAAAGAAGTTTTTGATGAAGCGAT
AGCTAAATTTAAAGATACAGACACTAAAATCGTGCATGATTTTGCTTATGGTGCTTTCGGTTTCGACGCTAAAAATCCTA
GTATACTTGCTTCGGAAAATGGGAAAGATGTTGCGATTGAAATTTATTCCTTGTCTAAAGGTTATAACATGTCAGGTTTT
AGAGTTGGTTTTGCAGTTGGTAATAAAGATATGATTCAAGCTTTGAAAAAGTACCAAACGCACACAAATGCTGGGATGTT
TGGTGCATTACAAGATGCCGCAATATATGCTTTGAATCATTATGATGATTTTTTAGAAGAACAAAGCAATGTATTTAAAG
CACGACGTGACCGATTCGAAGCCATGCTTGCAAAAGCTGATTTGCCATTTGTTCATGCTAAAGGTGGTATATATGTATGG
TTGGAAACACCGCCTGGTTATGACAGCGAGCAATTTGAGCAATTTTTAGTGAAAGAGAAGTCAATACTTGTTGCTCCAGG
GAAACCATTTGGAGAGAATGGTAATCGTTATGTGAGAATCTCATTGGCGTTAGATGACCAGCAATTAGACGAAGCTGCAA
TAAGATTAACAGAACTAGCATATTTATATGAATAA

Upstream 100 bases:

>100_bases
TGAATGGCGATGTCATTGTAACCACCTAAATGAGAGTGATACAAGTTGTTAGGATTATGATAGTCGCCCAGGCTATGTTT
AATGATAGAGGAGGAATTTG

Downstream 100 bases:

>100_bases
TAAAGTTAAGGGTGATGTTAAAATGACAAAAATTAAAATCATGAGTGTACGTGAAGAAGATATGCCTTATATCAAGGCGT
GGGCAGAGAAACATCATGTT

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQKALTIPENQKYGAFHGKEMFKQAIVDFYQR
QYDVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSKVDSQIKD
KTKLIYLTYPNNPTGSTATKEVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGF
RVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKARRDRFEAMLAKADLPFVHAKGGIYVW
LETPPGYDSEQFEQFLVKEKSILVAPGKPFGENGNRYVRISLALDDQQLDEAAIRLTELAYLYE

Sequences:

>Translated_384_residues
MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQKALTIPENQKYGAFHGKEMFKQAIVDFYQR
QYDVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSKVDSQIKD
KTKLIYLTYPNNPTGSTATKEVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGF
RVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKARRDRFEAMLAKADLPFVHAKGGIYVW
LETPPGYDSEQFEQFLVKEKSILVAPGKPFGENGNRYVRISLALDDQQLDEAAIRLTELAYLYE
>Mature_384_residues
MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQKALTIPENQKYGAFHGKEMFKQAIVDFYQR
QYDVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSKVDSQIKD
KTKLIYLTYPNNPTGSTATKEVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGF
RVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKARRDRFEAMLAKADLPFVHAKGGIYVW
LETPPGYDSEQFEQFLVKEKSILVAPGKPFGENGNRYVRISLALDDQQLDEAAIRLTELAYLYE

Specific function: Catalyzes the formation of methionine from 2-keto-4- methylthiobutyrate (KMTB) (Probable) [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. MtnE subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=378, Percent_Identity=23.8095238095238, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI56713254, Length=378, Percent_Identity=23.8095238095238, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI95147551, Length=388, Percent_Identity=20.360824742268, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI169881279, Length=388, Percent_Identity=20.360824742268, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1788722, Length=350, Percent_Identity=32.8571428571429, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786816, Length=381, Percent_Identity=22.0472440944882, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788627, Length=370, Percent_Identity=25.4054054054054, Blast_Score=88, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=390, Percent_Identity=25.6410256410256, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=390, Percent_Identity=25.6410256410256, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17567663, Length=337, Percent_Identity=27.0029673590504, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=395, Percent_Identity=22.5316455696203, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=22.5063938618926, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI18859735, Length=407, Percent_Identity=26.2899262899263, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573069, Length=414, Percent_Identity=20.5314009661836, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24646114, Length=414, Percent_Identity=20.5314009661836, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573067, Length=414, Percent_Identity=20.5314009661836, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573065, Length=414, Percent_Identity=20.5314009661836, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42839; Mature: 42839

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQKALTIPENQK
CCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCC
YGAFHGKEMFKQAIVDFYQRQYDVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPD
CCCCHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEECCCCEEEEEEEEECCCCEEEECC
PGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSKVDSQIKDKTKLIYLTYPNNPTGSTATK
CCCHHHHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
EVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGF
HHHHHHHHHHCCCCHHEEHHHHCCEECCCCCCCCEEECCCCCEEEEEEEEECCCCCCCCE
RVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKARRDRFE
EEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHH
AMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQFLVKEKSILVAPGKPFGENGNRYVRI
HHHHHCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEE
SLALDDQQLDEAAIRLTELAYLYE
EEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQKALTIPENQK
CCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCC
YGAFHGKEMFKQAIVDFYQRQYDVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPD
CCCCHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEEECCCCEEEEEEEEECCCCEEEECC
PGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSKVDSQIKDKTKLIYLTYPNNPTGSTATK
CCCHHHHHHEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
EVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGF
HHHHHHHHHHCCCCHHEEHHHHCCEECCCCCCCCEEECCCCCEEEEEEEEECCCCCCCCE
RVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKARRDRFE
EEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHH
AMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQFLVKEKSILVAPGKPFGENGNRYVRI
HHHHHCCCCEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEE
SLALDDQQLDEAAIRLTELAYLYE
EEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]