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The map label for this gene is gntK

Identifier: 82752087

GI number: 82752087

Start: 2513406

End: 2514959

Strand: Reverse

Name: gntK

Synonym: SAB2378c

Alternate gene names: 82752087

Gene position: 2514959-2513406 (Counterclockwise)

Preceding gene: 82752088

Following gene: 82752086

Centisome position: 91.7

GC content: 37.77

Gene sequence:

>1554_bases
ATGAAATATATGATTGGTGTCGACATTGGAACGACGAGTACCAAGTCAGTCTTATATGATGAAAATGGAACTTTCATCAT
GAAACATCAAATCGGCTATGATTTACACACACCAAACGTTGATGTCTCAGAAGAAAACCCAGATGAATTATTTGATGCGG
TATTAATGACAATTAAATACATAATGAGGGAATCGAAAGTTAATCAAGATGATATTAAATTTGTGTCATTTAGTGCGCAA
ATGCATAGCTTGATTGCGATGGATCAGCAACATCAAAGATTAACAAATAATATTACTTGGGCAGATAACCGCGCTGCAAA
ATATGCAACAGTAATAAACGAAGTGCATGATGGCAATGCGATTTATCAGCGAACAGGTACGCCTATTCATCCTATGTCGC
CATTAGCGAAGATTTTTTGGATGAAACATGAATGGCAAGATGTATTTCAACGTACTACTAAATTTGCAGATATTAAAACA
TACATTTTCTATCATTTGTTTGATAGATATATCATTGATTATTCAATGGCTTCCGCAACAGGGATGTTTAATTTAGAAAC
ATTAGATTGGGATGTTGGGGCATTAGAATTGCTTGGTATTTCCGAGGAAATGTTGCCGGAATTAGTGCCAACAACGTACG
TGATGAAAGGCATGAAAGAACGTTATGCAACATTAATGGGGCTTAATGAAGATACACCGTTTGTTATTGGTGCGAGTGAT
GGGGTCCTTTCTAATTTGGGTGTCAATAGTGTTGGTAAAGGAGAAGTTGCTGTCACAATCGGTACATCTGGGGCGATTCG
TACTGTGATAGATAAACCACGTACTGATTACAAAGGTAGAATATTTTGTTATGTCTTAACAGAGGACCACTACGTCATTG
GAGGCCCTGTAAATAATGGTGGTGTCGTATTGAGATGGTTGCGCGATGAGTTGTTAGCAAGTGAAGTTGAAACTGCGAAA
CGTCTCGGTGTTGATCCTTATGATGTTTTAACTCAAATTGCAAAGCGTGTTAAACCAGGTGCAGATGGTTTAATATTCCA
TCCCTATTTAGCTGGAGAACGTGCGCCGCTTTGGAACGCAAATGCAAGAGGTTCATTCTTCGGTTTAACTTTATCTCATA
AAAAAGAACATATGATTCGCGCCGCATTAGAAGGTGTTCTTTACAATTTGTATACCGTCTATCTTGCGCTTATTGAAGTA
ATGAATGAAACGCCTAAGATGATAAAAGCAACAGGTGGTTTTGCGAAAAGTGAAGTATGGCGTCAAATGATGTCAGATAT
ATTTGACACAGAGTTAGTGGTTCCTGAAAGTTATGAAAGTTCATGCTTAGGTGCCTGCGTACTCGGACTTAAAGCTGTAG
GTGACATTGAAGATTTTTCAATCGTTTCATCGATGGTCGGTGCCACAAACAATCATACGCCGATTGAAGAAAATGTCGCT
GTTTACCAAGAGCTCGTATCCATTTTTATCAATTTAAGTCGTTCTTTAACAGAGAATTATGAACAAATTGCAGATTTTCA
ACGCCAACATATGGCTGAAAATAAAACACAATAA

Upstream 100 bases:

>100_bases
TCAAATTTTGAAAGAAGCGTTTCATTTAAATTTCGACGATGTTGGTAAAGATATTGAAGGATTTTGGTTGAATTAAAATG
AAAAGAAAGAAGGATTTGTC

Downstream 100 bases:

>100_bases
ATACGTCACTCAAGCATCTTAGATAAAGTTGTTGTGCCATGACTACTATATATTATGTGGAATATGTGCGCGACGACGGT
GTTACATTCTATTGAAAAGA

Product: gluconokinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQ
MHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTTKFADIKT
YIFYHLFDRYIIDYSMASATGMFNLETLDWDVGALELLGISEEMLPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAK
RLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEV
MNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVA
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ

Sequences:

>Translated_517_residues
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQ
MHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTTKFADIKT
YIFYHLFDRYIIDYSMASATGMFNLETLDWDVGALELLGISEEMLPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAK
RLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEV
MNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVA
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
>Mature_517_residues
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQ
MHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTTKFADIKT
YIFYHLFDRYIIDYSMASATGMFNLETLDWDVGALELLGISEEMLPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAK
RLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEV
MNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVA
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=459, Percent_Identity=24.400871459695, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI189409120, Length=459, Percent_Identity=24.400871459695, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI4504007, Length=459, Percent_Identity=24.400871459695, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI41393575, Length=448, Percent_Identity=22.9910714285714, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI88196792, Length=489, Percent_Identity=23.3128834355828, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1789987, Length=498, Percent_Identity=25.7028112449799, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787789, Length=503, Percent_Identity=25.0497017892644, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1790361, Length=465, Percent_Identity=26.4516129032258, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790005, Length=524, Percent_Identity=23.6641221374046, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1789168, Length=461, Percent_Identity=20.824295010846, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789138, Length=516, Percent_Identity=23.062015503876, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=468, Percent_Identity=24.7863247863248, Blast_Score=118, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6321755, Length=360, Percent_Identity=24.7222222222222, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17864214, Length=487, Percent_Identity=24.2299794661191, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24655555, Length=447, Percent_Identity=25.503355704698, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24655560, Length=447, Percent_Identity=25.503355704698, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24655570, Length=447, Percent_Identity=25.503355704698, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24655574, Length=447, Percent_Identity=25.503355704698, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24655565, Length=447, Percent_Identity=25.503355704698, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24656367, Length=507, Percent_Identity=22.6824457593688, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI21357867, Length=518, Percent_Identity=22.972972972973, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24654573, Length=413, Percent_Identity=24.455205811138, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24656372, Length=323, Percent_Identity=25.3869969040248, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 58112; Mature: 58112

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKY
CCEEEEEECCCCCCCEEEEECCCCEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHH
IMRESKVNQDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNA
HHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
IYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTTKFADIKTYIFYHLFDRYIIDYSMASAT
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMFNLETLDWDVGALELLGISEEMLPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
CCEEEEEECCCCCCCEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNG
CHHHHCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEEEEEEECCCEEEECCCCCC
GVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNA
CEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
NARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPKMIKATGGFAKSEVW
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCHHHHHH
RQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVA
HHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKYMIGVDIGTTSTKSVLYDENGTFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKY
CCEEEEEECCCCCCCEEEEECCCCEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHH
IMRESKVNQDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNA
HHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
IYQRTGTPIHPMSPLAKIFWMKHEWQDVFQRTTKFADIKTYIFYHLFDRYIIDYSMASAT
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GMFNLETLDWDVGALELLGISEEMLPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
CCEEEEEECCCCCCCEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNG
CHHHHCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEEEEEEECCCEEEECCCCCC
GVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNA
CEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
NARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPKMIKATGGFAKSEVW
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCHHHHHH
RQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPIEENVA
HHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]