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The map label for this gene is panE [C]

Identifier: 82752039

GI number: 82752039

Start: 2459278

End: 2460213

Strand: Reverse

Name: panE [C]

Synonym: SAB2325c

Alternate gene names: 82752039

Gene position: 2460213-2459278 (Counterclockwise)

Preceding gene: 82752040

Following gene: 82752038

Centisome position: 89.71

GC content: 35.04

Gene sequence:

>936_bases
ATGAAAATTGCAATTGCTGGATCGGGTGCATTAGGTAGTGGCTTTGGTGCCAAACTATTTCAAGCAGGATATGATGTCAC
ACTTATTGACGGATATACATCTCATGTTGAAGCGGTTAAGCAACATGGATTAAATATAACGATTAATGGAGAGGCATTCG
AGTTAAACATTCCGATGTATCATTTTAATGATCAACCGGACGAAAGCATTTACGATGTTGTCTTTCTATTTCCAAAGTCT
ATGCAATTAAAAGAAGTGATGGAAGCTATGAAGCCACATATTGATAATGAAACGATTGTCGTATGTACGATGAATGGTTT
GAAGCATGAAGAAGTCATTGCGCAGTATGTTGCTCAATCACAAATTGTCAGAGGTGTTACGACTTGGACGGCAGGTCTTG
AAAGCCCTGGACACAGTCATTTACTTGGTAGTGGACCAGTTGAAATAGGTGAACTAGTTGATGAAGGTAAAGAAAATGTT
ATAAAAGTTGCTGATTTACTTAACGAAGCGGAATTGAATGGTGTCATTAGTAAAGATTTATACCAATCGATTTGGAAAAA
GATTTGTGTTAATGGTACGGCAAATGCATTAAGCACAGTGTTGGAGTGTAATATGGCATCACTGAATGAAAGTAGTTATG
CGAAGTGTTTGATTTATAAATTAACGCAAGAAATAGTGCATGTAGCGACGATTGATAATGTTCATTTAAATGTTGATGAA
ATATTTGAATATTTAGTTGATTTAAATGAAAAAGTTGGTGCGCATTATCCATCCATGTATCAAGATTTAATTGTTAATAA
TAGAAAAACTGAAATTGATTATATTAATGGCGCAGTTGCAACATTAGGTAAACAACGTCATATTGAAGCGCCAGTCAATC
GCTTTATTACTGATTTAATTCATACTAAAGAAAGTCAGCGACATGCACAGGATTAA

Upstream 100 bases:

>100_bases
AAAGCTGTGTGTATATTAAGCGAATGATTTTCAAATTGACGCTAATATGCGAAAGTAGTATTTTAAAAATGAACAACAAC
GATGAAGAGGGGTTTATAGG

Downstream 100 bases:

>100_bases
TTAGTGCTTTTAGGTATGATTGCAAGGAAATGACAATCACGTGATAATTACGGTCATTATTAAAATTGAAATGTAATAAA
TAAAGAACAGCAGTAAGGTA

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKIAIAGSGALGSGFGAKLFQAGYDVTLIDGYTSHVEAVKQHGLNITINGEAFELNIPMYHFNDQPDESIYDVVFLFPKS
MQLKEVMEAMKPHIDNETIVVCTMNGLKHEEVIAQYVAQSQIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENV
IKVADLLNEAELNGVISKDLYQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLIYKLTQEIVHVATIDNVHLNVDE
IFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYINGAVATLGKQRHIEAPVNRFITDLIHTKESQRHAQD

Sequences:

>Translated_311_residues
MKIAIAGSGALGSGFGAKLFQAGYDVTLIDGYTSHVEAVKQHGLNITINGEAFELNIPMYHFNDQPDESIYDVVFLFPKS
MQLKEVMEAMKPHIDNETIVVCTMNGLKHEEVIAQYVAQSQIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENV
IKVADLLNEAELNGVISKDLYQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLIYKLTQEIVHVATIDNVHLNVDE
IFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYINGAVATLGKQRHIEAPVNRFITDLIHTKESQRHAQD
>Mature_311_residues
MKIAIAGSGALGSGFGAKLFQAGYDVTLIDGYTSHVEAVKQHGLNITINGEAFELNIPMYHFNDQPDESIYDVVFLFPKS
MQLKEVMEAMKPHIDNETIVVCTMNGLKHEEVIAQYVAQSQIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENV
IKVADLLNEAELNGVISKDLYQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLIYKLTQEIVHVATIDNVHLNVDE
IFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYINGAVATLGKQRHIEAPVNRFITDLIHTKESQRHAQD

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=310, Percent_Identity=23.2258064516129, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 34415; Mature: 34415

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIAGSGALGSGFGAKLFQAGYDVTLIDGYTSHVEAVKQHGLNITINGEAFELNIPMY
CEEEEECCCCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEECCCEEEEECCEE
HFNDQPDESIYDVVFLFPKSMQLKEVMEAMKPHIDNETIVVCTMNGLKHEEVIAQYVAQS
ECCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
QIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENVIKVADLLNEAELNGVISKDL
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
YQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLIYKLTQEIVHVATIDNVHLNVDE
HHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHEECCEEECHHH
IFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYINGAVATLGKQRHIEAPVNRFITDLI
HHHHHHCCHHHHCCCCHHHHHHHHHCCCCCEEHHHCCHHHHHCCCCCCHHHHHHHHHHHH
HTKESQRHAQD
HHCHHHHCCCC
>Mature Secondary Structure
MKIAIAGSGALGSGFGAKLFQAGYDVTLIDGYTSHVEAVKQHGLNITINGEAFELNIPMY
CEEEEECCCCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEECCCEEEEECCEE
HFNDQPDESIYDVVFLFPKSMQLKEVMEAMKPHIDNETIVVCTMNGLKHEEVIAQYVAQS
ECCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
QIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENVIKVADLLNEAELNGVISKDL
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
YQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLIYKLTQEIVHVATIDNVHLNVDE
HHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHEECCEEECHHH
IFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYINGAVATLGKQRHIEAPVNRFITDLI
HHHHHHCCHHHHCCCCHHHHHHHHHCCCCCEEHHHCCHHHHHCCCCCCHHHHHHHHHHHH
HTKESQRHAQD
HHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]