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The map label for this gene is scrA

Identifier: 82751973

GI number: 82751973

Start: 2386572

End: 2388014

Strand: Reverse

Name: scrA

Synonym: SAB2257c

Alternate gene names: 82751973

Gene position: 2388014-2386572 (Counterclockwise)

Preceding gene: 82751979

Following gene: 82751970

Centisome position: 87.07

GC content: 35.41

Gene sequence:

>1443_bases
ATGAATTATAAGCAATCCGCAGAAGATATTTTGAACGCGATAGGCGGAGAAGAGAATTTAGATGCAATGGCGCATTGTGC
AACGAGACTACGATTAGTTTTAAATGATGAAAGTTTAGTAAATGAAGAGGCGCTAAACAATATGGATGTAGTTAAAGGGA
CATTTTCTACTGGGGGACAATACCAAATTATTATTGGGTCTGGTACAGTCAATAAAGTATTTAGTGAACTGGAAAAATTA
ACTGGAAAAGAAGCATCGACCACTTCGGAAGTCAAAGCACAATCTGCTAAAAATATGAATCCGTTACAGCGATTTGTAAA
AATGCTTTCAGATATCTTTGTTCCGATTATACCAGCCATCGTTGCTGGTGGTTTATTAATGGGGTTAAATAACATTTTGA
CTGCGAAAGATTTATTCTTTTCAGGTAAATCATTGATAGATGTATATAGTCAATTTGCTGGATTAGCTGAAATGATAAAT
GTTTTTGCGAATGCACCATTTACATTATTACCAATTTTAATTGGATTTAGTGCAGCAAAACGTTTTGGTGGCAATCCGTT
TTTAGGTGCTGCATTAGGTATGATATTGGTTCATCCATCGCTAATGAGCGCATACGATTTCCCAAAAGCAGTTGAAGCAG
GTAAGGCTATTCCATATTGGGATGTATTTGGTTTGCATATTAATCAAGTAGGTTATCAAGGACAAGTGTTACCTATGCTT
GTAGCAGCTTATATCTTAGCCTCAATTGAAAAAGGCTTACGCAAAGTTATTCCAACGGTGTTAGATAATTTGTTAACACC
ATTGTTATCTATTTTTATAACAGCATTTCTAACATTTTCATTTGTAGGTCCAATCACTCGTCAATTAGGTTACTGGTTAT
CAGATGGTTTAACATGGCTTTATGAATTTGGTGGTGCAATTGGTGGATTAATATTCGGATTATTGTATGCTCCGATTGTT
ATTACAGGTATGCATCATAGCTTTATAGCTGTAGAAACGACATTAATTGCAGATGCCACTAAAACGGGTGGATCATTTAT
ATTCCCGATTGCGACAATGTCTAATGTTGCACAAGGTGGTGCAGCAATTGCAGCGTTCTTTATTATTAAACAAAATAAGA
AGTTAAAAGGTGTGGCATCTGCCACAGGTATTTCAGCATTACTTGGTATTACAGAACCGGCTATGTTTGGTGTTAACTTA
AAACTAAGATATCCATTTATTGGCGCTATCGTTGGATCAGGTATTGGTTCAGCATATATTGCTTTCTTCAAGGTTAAAGC
AATCGCATTAGGAACTGCTGGATTGCCTGGATTTATTTCAATCAATCCAGTACATGCAGGATGGTTACACTACTTTGTTG
GTATGACAATATCATTCATCGTTGCTATAACAGTTACTTTAATTTTATCGAAAAGAAAAGCAAATAAAGAAGTTGTAGAA
TAA

Upstream 100 bases:

>100_bases
TTGTTTATATAAAATGATAATAGAGTGTTGCAAATATTTTTGGAACCGGTTACAATAAAGTGGAATAAATGGAACCGGTT
CTAATTAGGAGGCTAAATAT

Downstream 100 bases:

>100_bases
AAAAAGAGGTATGACAGTAATCAAAGTATCAGTCATTGCAAATGCAATAGGATGAAAATTTAAGCTGTCATACCTTTTAA
TTTAGTTATAATTTCTGTTT

Product: PTS system sucrose-specific IIBC component

Products: NA

Alternate protein names: EIIBC-Scr; EII-Scr; Sucrose-specific phosphotransferase enzyme IIB component; PTS system sucrose-specific EIIB component; Sucrose permease IIC component; PTS system sucrose-specific EIIC component [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MNYKQSAEDILNAIGGEENLDAMAHCATRLRLVLNDESLVNEEALNNMDVVKGTFSTGGQYQIIIGSGTVNKVFSELEKL
TGKEASTTSEVKAQSAKNMNPLQRFVKMLSDIFVPIIPAIVAGGLLMGLNNILTAKDLFFSGKSLIDVYSQFAGLAEMIN
VFANAPFTLLPILIGFSAAKRFGGNPFLGAALGMILVHPSLMSAYDFPKAVEAGKAIPYWDVFGLHINQVGYQGQVLPML
VAAYILASIEKGLRKVIPTVLDNLLTPLLSIFITAFLTFSFVGPITRQLGYWLSDGLTWLYEFGGAIGGLIFGLLYAPIV
ITGMHHSFIAVETTLIADATKTGGSFIFPIATMSNVAQGGAAIAAFFIIKQNKKLKGVASATGISALLGITEPAMFGVNL
KLRYPFIGAIVGSGIGSAYIAFFKVKAIALGTAGLPGFISINPVHAGWLHYFVGMTISFIVAITVTLILSKRKANKEVVE

Sequences:

>Translated_480_residues
MNYKQSAEDILNAIGGEENLDAMAHCATRLRLVLNDESLVNEEALNNMDVVKGTFSTGGQYQIIIGSGTVNKVFSELEKL
TGKEASTTSEVKAQSAKNMNPLQRFVKMLSDIFVPIIPAIVAGGLLMGLNNILTAKDLFFSGKSLIDVYSQFAGLAEMIN
VFANAPFTLLPILIGFSAAKRFGGNPFLGAALGMILVHPSLMSAYDFPKAVEAGKAIPYWDVFGLHINQVGYQGQVLPML
VAAYILASIEKGLRKVIPTVLDNLLTPLLSIFITAFLTFSFVGPITRQLGYWLSDGLTWLYEFGGAIGGLIFGLLYAPIV
ITGMHHSFIAVETTLIADATKTGGSFIFPIATMSNVAQGGAAIAAFFIIKQNKKLKGVASATGISALLGITEPAMFGVNL
KLRYPFIGAIVGSGIGSAYIAFFKVKAIALGTAGLPGFISINPVHAGWLHYFVGMTISFIVAITVTLILSKRKANKEVVE
>Mature_480_residues
MNYKQSAEDILNAIGGEENLDAMAHCATRLRLVLNDESLVNEEALNNMDVVKGTFSTGGQYQIIIGSGTVNKVFSELEKL
TGKEASTTSEVKAQSAKNMNPLQRFVKMLSDIFVPIIPAIVAGGLLMGLNNILTAKDLFFSGKSLIDVYSQFAGLAEMIN
VFANAPFTLLPILIGFSAAKRFGGNPFLGAALGMILVHPSLMSAYDFPKAVEAGKAIPYWDVFGLHINQVGYQGQVLPML
VAAYILASIEKGLRKVIPTVLDNLLTPLLSIFITAFLTFSFVGPITRQLGYWLSDGLTWLYEFGGAIGGLIFGLLYAPIV
ITGMHHSFIAVETTLIADATKTGGSFIFPIATMSNVAQGGAAIAAFFIIKQNKKLKGVASATGISALLGITEPAMFGVNL
KLRYPFIGAIVGSGIGSAYIAFFKVKAIALGTAGLPGFISINPVHAGWLHYFVGMTISFIVAITVTLILSKRKANKEVVE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=441, Percent_Identity=34.4671201814059, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1790159, Length=474, Percent_Identity=28.9029535864979, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI48994906, Length=482, Percent_Identity=28.4232365145228, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1788769, Length=499, Percent_Identity=28.2565130260521, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010973 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 51221; Mature: 51221

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKQSAEDILNAIGGEENLDAMAHCATRLRLVLNDESLVNEEALNNMDVVKGTFSTGGQ
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCHHHHHHHHHCCCHHHEEECCCCCE
YQIIIGSGTVNKVFSELEKLTGKEASTTSEVKAQSAKNMNPLQRFVKMLSDIFVPIIPAI
EEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
VAGGLLMGLNNILTAKDLFFSGKSLIDVYSQFAGLAEMINVFANAPFTLLPILIGFSAAK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RFGGNPFLGAALGMILVHPSLMSAYDFPKAVEAGKAIPYWDVFGLHINQVGYQGQVLPML
HCCCCCHHHHHHHHHHHCHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHH
VAAYILASIEKGLRKVIPTVLDNLLTPLLSIFITAFLTFSFVGPITRQLGYWLSDGLTWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YEFGGAIGGLIFGLLYAPIVITGMHHSFIAVETTLIADATKTGGSFIFPIATMSNVAQGG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCC
AAIAAFFIIKQNKKLKGVASATGISALLGITEPAMFGVNLKLRYPFIGAIVGSGIGSAYI
HHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCHHCCCEEEEECCHHHHHHHCCCHHHHH
AFFKVKAIALGTAGLPGFISINPVHAGWLHYFVGMTISFIVAITVTLILSKRKANKEVVE
HHHHHHHHHEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNYKQSAEDILNAIGGEENLDAMAHCATRLRLVLNDESLVNEEALNNMDVVKGTFSTGGQ
CCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCHHHHHHHHHCCCHHHEEECCCCCE
YQIIIGSGTVNKVFSELEKLTGKEASTTSEVKAQSAKNMNPLQRFVKMLSDIFVPIIPAI
EEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
VAGGLLMGLNNILTAKDLFFSGKSLIDVYSQFAGLAEMINVFANAPFTLLPILIGFSAAK
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RFGGNPFLGAALGMILVHPSLMSAYDFPKAVEAGKAIPYWDVFGLHINQVGYQGQVLPML
HCCCCCHHHHHHHHHHHCHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHH
VAAYILASIEKGLRKVIPTVLDNLLTPLLSIFITAFLTFSFVGPITRQLGYWLSDGLTWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YEFGGAIGGLIFGLLYAPIVITGMHHSFIAVETTLIADATKTGGSFIFPIATMSNVAQGG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCC
AAIAAFFIIKQNKKLKGVASATGISALLGITEPAMFGVNLKLRYPFIGAIVGSGIGSAYI
HHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCHHCCCEEEEECCHHHHHHHCCCHHHHH
AFFKVKAIALGTAGLPGFISINPVHAGWLHYFVGMTISFIVAITVTLILSKRKANKEVVE
HHHHHHHHHEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8232209 [H]