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The map label for this gene is moeB

Identifier: 82751864

GI number: 82751864

Start: 2281681

End: 2282685

Strand: Reverse

Name: moeB

Synonym: SAB2148c

Alternate gene names: 82751864

Gene position: 2282685-2281681 (Counterclockwise)

Preceding gene: 82751865

Following gene: 82751863

Centisome position: 83.23

GC content: 34.33

Gene sequence:

>1005_bases
GTGAGTCAAGAACGTTATTCAAGGCAAATTTTATTTAAACAAATAGGTGAAATAGGTCAAAGCAAAATAAATCAAAAATG
TGCGTTGATTATTGGTATGGGCGCATTAGGTACACATGTGGCTGAAGGACTTGTTAGAGCAGGTATTGCTAAACTAATCA
TTGTTGATAGAGATTATATTGAATTTAGTAATTTACAAAGACAAACATTGTTTACTGAAGAAGATGCTTTGAAAATGATG
CCTAAAGTGGTTGCAGCTAAAAAGCATTTGCTAGCGTTACGTAGTGATGTTGATATTGATGATTATATTGCCCATGTGGA
TTATTATTTTTTAGAAACACATGAACAGGACGTTGACGTTATTATTGATGCAACCGATAACTTTGAAACACGACAACTGA
TTAATGATTTTGCTTATAAACATCGTATACCTTGGATTTATGGTGGTGTTGTACAGAGTACATATACAGAAGCTGCATTT
ATACCTGGTAAAACACCTTGCTTTAACTGTTTGGTACCACAATTGCCAGCATTAAATTTAACATGTGATACAGTAGGGGT
CATTCAACCTGCCGTGACGATGGCAACAAGTTTACAATTAAGAGATGCGATGAAAGTATTAACGGAACACCCAATTGACA
CAAAAATAACTTATGGCGATATTTGGGAAGGTAGTCATTATTCATTTGGTTTCAGTAAAATGCAACGTTCAGCCTGTACA
ACTTGTGGAGATGTACCAAGTTATCCGTATTTAAACAAAAATGAACAACGTTATGCAACATTGTGTGGTAGAGACACTGT
ACAGTATGAAAATGCATCAATTACACACGACATTCTTGTTCAATTTTTAAAACAACATCAGTTAAATTATCGCAGTAATT
CGTATATGGTTATGTTTGAATTTAAAGGACACCGCATTGTTGCTTTTAAAGGTGGAAGGTTTTTAATACATGGCATGACA
CGCACATCAGATGCCACACATCTAATGAATTTATTGTTTGGATAA

Upstream 100 bases:

>100_bases
TTTAATGATGTTTTAAACTCTTTTTTAGGGGCAGTTTTTTGAGAGACATTGACGCGCGTCATATAATGAAAGTAATGATA
AAAAGAAAGGATAACTTAAT

Downstream 100 bases:

>100_bases
AAAAAGATAAGACAAAAGGAGTGTAATATTATGGGCGAACATCAAAACGTTAAATTGAATCGTACAGTTAAAGCAGCCGT
ACTAACGGTATCAGATACTA

Product: molybdopterin biosynthesis protein

Products: NA

Alternate protein names: MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMM
PKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHEQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAF
IPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEHPIDTKITYGDIWEGSHYSFGFSKMQRSACT
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMT
RTSDATHLMNLLFG

Sequences:

>Translated_334_residues
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMM
PKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHEQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAF
IPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEHPIDTKITYGDIWEGSHYSFGFSKMQRSACT
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMT
RTSDATHLMNLLFG
>Mature_333_residues
SQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMP
KVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHEQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFI
PGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEHPIDTKITYGDIWEGSHYSFGFSKMQRSACTT
CGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTR
TSDATHLMNLLFG

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein moaD [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=172, Percent_Identity=33.1395348837209, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI13376212, Length=248, Percent_Identity=27.0161290322581, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787048, Length=243, Percent_Identity=30.0411522633745, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87082356, Length=247, Percent_Identity=33.1983805668016, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17540406, Length=248, Percent_Identity=30.6451612903226, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17508819, Length=182, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=271, Percent_Identity=25.0922509225092, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320598, Length=170, Percent_Identity=28.8235294117647, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24582879, Length=254, Percent_Identity=29.1338582677165, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641311, Length=260, Percent_Identity=29.2307692307692, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 37932; Mature: 37801

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYI
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCHHEEEEEECCHH
EFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHEQDVDV
HHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCCEEE
IIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNL
EEECCCCHHHHHHHHHHHHHHCCCEEECCHHHHHCCCEEECCCCCCHHHHHCCCCCCCEE
TCDTVGVIQPAVTMATSLQLRDAMKVLTEHPIDTKITYGDIWEGSHYSFGFSKMQRSACT
EECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHC
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFE
CCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
FKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
ECCCEEEEEECCEEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYI
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCHHEEEEEECCHH
EFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHEQDVDV
HHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEECCCCCEEE
IIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNL
EEECCCCHHHHHHHHHHHHHHCCCEEECCHHHHHCCCEEECCCCCCHHHHHCCCCCCCEE
TCDTVGVIQPAVTMATSLQLRDAMKVLTEHPIDTKITYGDIWEGSHYSFGFSKMQRSACT
EECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHC
TCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFE
CCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEEE
FKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
ECCCEEEEEECCEEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]