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The map label for this gene is mtlD

Identifier: 82751756

GI number: 82751756

Start: 2172642

End: 2173748

Strand: Direct

Name: mtlD

Synonym: SAB2039

Alternate gene names: 82751756

Gene position: 2172642-2173748 (Clockwise)

Preceding gene: 82751755

Following gene: 82751771

Centisome position: 79.22

GC content: 33.06

Gene sequence:

>1107_bases
ATGAAAGCAGTTCACTTTGGTGCTGGTAACATAGGTCGTGGTTTCATTGGTTATATTCTTGCAGACAACAATGTTAAAGT
AACATTTGCAGATGTCAATGAAGAAATCATTAATGCTTTAGCTCATGATCATCAATACGATGTTATTTTAGCTGATGAGT
CTAAAACAACGACGCGCGTGAATAATGTTGATGCAATTAATTCAATGCAACCTTCTGAAGCGTTGAAACAAGCAATTCTA
GAAGGTGATATTATTACAACAGCTGTTGGTGTTAACATACTACCTATTATTGCTAAATCTTTTGCGCCTTTCTTAAAAGA
AAAAACAAACCATGTTAATATTGTTGCTTGTGAGAATGCTATTATGGCAACTGATACATTGAAAAAAGCGGTACTTGATA
TTACTGGCCCTCTTGGTAACAATATTCATTTTGCTAACTCAGCAGTTGATAGAATTGTACCATTACAAAAGAATGAAAAT
ATATTAGATGTTATGGTTGAGCCATTTTACGAATGGGTTGTTGAAAAAGATGCATGGTATGGTCCAGAACTAAATCATAT
TAAATATGTTGATGATTTAACACCATATATTGAGCGTAAATTATTAACTGTGAATACAGGACATGCATATTTAGCGTATG
CTGGTAAATTTGCAGATAAAGCTACCGTATTAGACGCTGTAAAAGATAGTTCAATTGAAGCTGGCTTACGCCGTGTTTTA
GCTGAAACAAGTCAATATATTACTAATGAATTTGATTTTACTGAAGCGGAACAAGCTGGTTATGTTGAAAAAATAATAGA
CCGTTTCAACAATTCTTATTTATCTGATGAAGTAACACGAGTCGGACGAGGTACGTTACGTAAAATTGGCCCTAAAGATA
GAATTATAAAACCATTAACATATCTTTATAATAAAGATTTAGAACGCACTGGTTTATTAAATACAGCTGCATTGTTATTG
AAGTATGATGATACAGCAGACCAAGAAACTGTTGAGAAAAATAATTACATTAAAGAACACGGTTTAAAAGCGTTCTTAAG
CGAATATGCTAAAGTTGACGATGGCTTAGCCGATGAAATAATTGAAGCGTACAATTCACTTTCATAA

Upstream 100 bases:

>100_bases
AAATTGCAATTACATTTAGCGAAGAAGAAAATGTGGATCGTATCGTTCAAGCAAAATCTGCAGAAGAAATTAAACAAGTA
TTCGAGGAGGCAGATGCATA

Downstream 100 bases:

>100_bases
TTTATTGAGCTTTGTTTGAAACAAGAAGTTTCCAACGTTATTCGTTAACAATCAGTAATAATGTAGTAGTTCCGTTGAAT
TAACAATATTAAATTTCTGA

Product: mannitol-1-phosphate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAIL
EGDIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFADKATVLDAVKDSSIEAGLRRVL
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLL
KYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

Sequences:

>Translated_368_residues
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAIL
EGDIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFADKATVLDAVKDSSIEAGLRRVL
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLL
KYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>Mature_368_residues
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAIL
EGDIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFADKATVLDAVKDSSIEAGLRRVL
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLL
KYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1790028, Length=388, Percent_Identity=36.340206185567, Blast_Score=238, Evalue=5e-64,
Organism=Escherichia coli, GI1788497, Length=206, Percent_Identity=26.2135922330097, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR023028
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.17 [H]

Molecular weight: Translated: 40981; Mature: 40981

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRV
CCEEEECCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCEEC
NNVDAINSMQPSEALKQAILEGDIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENA
CCCCHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
IMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWY
HHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFADKATVLDAVKDSSIEAGLRRVL
CCCCCCEEEHHHHHHHHCCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHH
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLT
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHH
YLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEI
HHHCCCCHHHCCHHHEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
IEAYNSLS
HHHHHCCC
>Mature Secondary Structure
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRV
CCEEEECCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCEEC
NNVDAINSMQPSEALKQAILEGDIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENA
CCCCHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
IMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWY
HHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFADKATVLDAVKDSSIEAGLRRVL
CCCCCCEEEHHHHHHHHCCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCHHHHHHHHHH
AETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLT
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHH
YLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEI
HHHCCCCHHHCCHHHEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
IEAYNSLS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA