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The map label for this gene is luxS

Identifier: 82751735

GI number: 82751735

Start: 2150506

End: 2150976

Strand: Direct

Name: luxS

Synonym: SAB2018

Alternate gene names: 82751735

Gene position: 2150506-2150976 (Clockwise)

Preceding gene: 82751731

Following gene: 82751739

Centisome position: 78.41

GC content: 33.55

Gene sequence:

>471_bases
ATGACAAAAATGAATGTTGAAAGTTTCAATTTAGATCATACTAAAGTGGTTGCTCCATTTATTAGATTAGCGGGAACGAT
GGAAGGATTAAACGGAGATGTCATTTACAAATATGACATTCGTTTCAAACAACCAAACAAAGAACATATGGATATGCCTG
GATTGCATTCATTAGAACATTTAATGGCTGAAAATATTAGAAATCATAGTGACAAAGTCGTTGATTTAAGTCCTATGGGT
TGCCAAACTGGTTTCTATGTATCATTTATTAATCATGATAATTATGATGATGTATTAAATATTGTTGAAGCAACTTTAAA
TGATGTGCTAAATGCTACTGAAGTGCCTGCTTGTAATGAAGTACAATGTGGCTGGGCAGCAAGTCATTCATTAGAAGGTG
CTAAAACTATCGCTCAAGCATTTCTAGACAAACGAAACGAATGGCATGATGTTTTCGGTACAGGAAAATAA

Upstream 100 bases:

>100_bases
AGTATTGTTAGAAACGCAACTTGCAACAAATTTAAGTTTAATATTGTACCAAATTATAAACGTTTTATAGTTTTGAGTAG
TTAATAGGAGGAAATTTAAA

Downstream 100 bases:

>100_bases
AGCTTAGTCAATCAAGTTAATCAGAAAAGCAGTCGAACAATGATGTTACAATCGCCATTGTCCAACTGCTTTTTATTATG
CTTCAAAATCAAAAAATCGA

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIYKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMG
CQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK

Sequences:

>Translated_156_residues
MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIYKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMG
CQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
>Mature_155_residues
TKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIYKYDIRFKQPNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMGC
QTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=146, Percent_Identity=41.7808219178082, Blast_Score=120, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 17540; Mature: 17409

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIYKYDIRFKQPNKEHMDMPGLHSLEH
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHCCCCCHHHHHH
LMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNE
HHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
VQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIYKYDIRFKQPNKEHMDMPGLHSLEH
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHCCCCCHHHHHH
LMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIVEATLNDVLNATEVPACNE
HHHHHHCCCCCCEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
VQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA