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The map label for this gene is mazF [H]

Identifier: 82751671

GI number: 82751671

Start: 2086904

End: 2087257

Strand: Reverse

Name: mazF [H]

Synonym: SAB1953c

Alternate gene names: 82751671

Gene position: 2087257-2086904 (Counterclockwise)

Preceding gene: 82751672

Following gene: 82751670

Centisome position: 76.11

GC content: 33.05

Gene sequence:

>354_bases
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAATTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCATTAG

Upstream 100 bases:

>100_bases
TGGCTGATTTAAATCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTA
TCTTCTAATTCAACGAATGA

Downstream 100 bases:

>100_bases
AAAAATTAGGCGTCTATTATATGTATTTTTCAGAGATAAATAAAATATTGATATAAAAGACAATAACTTTATAATAATTA
TAACTATTTCTAAATTTTGT

Product: hypothetical protein

Products: NA

Alternate protein names: Endoribonuclease MazF; Toxin MazF [H]

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIR
TLDKKRLKEKLTYLSDDKMKEVDNALMISLGLNAVAH

Sequences:

>Translated_117_residues
MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIR
TLDKKRLKEKLTYLSDDKMKEVDNALMISLGLNAVAH
>Mature_117_residues
MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIR
TLDKKRLKEKLTYLSDDKMKEVDNALMISLGLNAVAH

Specific function: Part of a toxin-antitoxin (TA) module. Ribosome- independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. Cleavages occur preferentially in a U-rich region with a consensus sequenc

COG id: COG2337

COG function: function code T; Growth inhibitor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PemK/MazF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003477
- InterPro:   IPR011067 [H]

Pfam domain/function: PF02452 PemK [H]

EC number: NA

Molecular weight: Translated: 13071; Mature: 13071

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVE
CCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEE
IEKKKYKLDKDSVILLEQIRTLDKKRLKEKLTYLSDDKMKEVDNALMISLGLNAVAH
EEHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCHHHCC
>Mature Secondary Structure
MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVE
CCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEE
IEKKKYKLDKDSVILLEQIRTLDKKRLKEKLTYLSDDKMKEVDNALMISLGLNAVAH
EEHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA