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The map label for this gene is gcp [H]

Identifier: 82751652

GI number: 82751652

Start: 2060786

End: 2061811

Strand: Reverse

Name: gcp [H]

Synonym: SAB1934c

Alternate gene names: 82751652

Gene position: 2061811-2060786 (Counterclockwise)

Preceding gene: 82751653

Following gene: 82751648

Centisome position: 75.18

GC content: 37.43

Gene sequence:

>1026_bases
ATGACTAAAGATATATTAATACTAGCTGTTGAAACAAGTTGTGATGAAACAAGCGTTAGTGTTATAAAAAATGGCAGAGA
TATTTTATCAAATACAGTTTTAAGTCAGATTGAAAGTCATAAACGATTTGGCGGTGTCGTTCCCGAAGTGGCAAGTAGAC
ATCACGTTGAAGGTATAACAACAACAATAAACGAGGCTCTAGTGGATGCCGATGTATCAATGGAAGATATTGATGCCATA
GCGGTTACAGAAGGCCCTGGACTAATTGGTGCGTTACTAATAGGTGTTAATGCAGCCAAAGCATTGGCATTTGCTTACGA
TAAGCCACTTATTCCAGTTCATCATATTGCAGGACATATATATGCTAATCACATAGAAGATCTATTAACATTCCCGCTAA
TTGCACTTATTGTCTCAGGTGGACATACTGAATTAGTTTATATGAAAGATCATTTAACATTTGAAGTCATTGGTGAAACA
CGAGATGACGCAGTAGGTGAGGCTTATGATAAAGTGGCACGAACAATTGGTTTAAATTATCCAGGTGGTCCACAAGTTGA
TCGGTTGGCTGCTGAAGGTGAAGATACTTATTCATTCCCTCGTGTTTGGTTGGATAAAGATAGTTATGATTTTAGTTTTA
GTGGGTTGAAAAGTGCCGTAATCAATCAACTTCACAATCAACGACAAAAAAATATTCCAATCATTGAAGCTAACGTAGCA
ACGAGCTTTCAAAATAGTGTTGTAGAGGTGCTTACGTTTAAAGCTATTCAAGCTTGTAAAGAATATGGTGTTCAGCGATT
AATTGTTGCTGGTGGCGTGGCGAGTAATAAAGGATTACGTCAATCTTTAGCGGATCAATGCAAAGTCAATGACATTCAAT
TAACTATCCCAAGTCCTAAATTATGCACAGATAATGCTGCAATGATAGGCGTTGCCGGCCACTATTTGTATCAGCAAGGT
CGATTTGCTGATTTAGGATTAAATGGGCACAGCAATATAGATTTAGAAGAGTATTCTGCAGAATAA

Upstream 100 bases:

>100_bases
GCACAACATGTATATGAAAATTTAGGATTTCAATATGGTGGTAAACGTAAAAATTATTATGGTGAAGGTGAGGACGCAAT
GGTTATGTGGGTGAATTTAA

Downstream 100 bases:

>100_bases
AATAAACGTCAGTTATTAACATGATTACGATGAACATTATTGAAACTGTTCACTGTCTTCTGTCATGTGATAGCTGACGT
TTTTATATTGCAATTAGGGA

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITTTINEALVDADVSMEDIDAI
AVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEDLLTFPLIALIVSGGHTELVYMKDHLTFEVIGET
RDDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
TSFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHYLYQQG
RFADLGLNGHSNIDLEEYSAE

Sequences:

>Translated_341_residues
MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITTTINEALVDADVSMEDIDAI
AVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEDLLTFPLIALIVSGGHTELVYMKDHLTFEVIGET
RDDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
TSFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHYLYQQG
RFADLGLNGHSNIDLEEYSAE
>Mature_340_residues
TKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITTTINEALVDADVSMEDIDAIA
VTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEDLLTFPLIALIVSGGHTELVYMKDHLTFEVIGETR
DDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVAT
SFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHYLYQQGR
FADLGLNGHSNIDLEEYSAE

Specific function: Critical mediator involved in the modification of cell wall peptidoglycan synthesis and/or cell division. Essential for cell viability [H]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=332, Percent_Identity=32.5301204819277, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI8923380, Length=326, Percent_Identity=30.3680981595092, Blast_Score=135, Evalue=6e-32,
Organism=Escherichia coli, GI1789445, Length=336, Percent_Identity=42.5595238095238, Blast_Score=290, Evalue=7e-80,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=30.4615384615385, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=333, Percent_Identity=29.4294294294294, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320099, Length=355, Percent_Identity=30.4225352112676, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6322891, Length=294, Percent_Identity=27.5510204081633, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20129063, Length=334, Percent_Identity=30.2395209580838, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI21357207, Length=330, Percent_Identity=28.1818181818182, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36911; Mature: 36780

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGIT
CCCCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHH
TTINEALVDADVSMEDIDAIAVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHI
HHHHHHHHCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YANHIEDLLTFPLIALIVSGGHTELVYMKDHLTFEVIGETRDDAVGEAYDKVARTIGLNY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
PGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
CCCCCHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHH
TSFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPK
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCC
LCTDNAAMIGVAGHYLYQQGRFADLGLNGHSNIDLEEYSAE
CCCCCCEEEEHHHHHHHHCCCEEEECCCCCCCCCHHHCCCC
>Mature Secondary Structure 
TKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGIT
CCCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHH
TTINEALVDADVSMEDIDAIAVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHI
HHHHHHHHCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YANHIEDLLTFPLIALIVSGGHTELVYMKDHLTFEVIGETRDDAVGEAYDKVARTIGLNY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
PGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
CCCCCHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHH
TSFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPK
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCC
LCTDNAAMIGVAGHYLYQQGRFADLGLNGHSNIDLEEYSAE
CCCCCCEEEEHHHHHHHHCCCEEEECCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA