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The map label for this gene is ygcA [C]

Identifier: 82751550

GI number: 82751550

Start: 1962937

End: 1964298

Strand: Reverse

Name: ygcA [C]

Synonym: SAB1829c

Alternate gene names: 82751550

Gene position: 1964298-1962937 (Counterclockwise)

Preceding gene: 82751551

Following gene: 82751549

Centisome position: 71.62

GC content: 33.04

Gene sequence:

>1362_bases
TTGCAAGCAATAGCTAAAAATGACATTAAAACGGGAACAGTTGTTGATTTAACGCATGAAGGCCATGGTGTCGTAAAAAT
AGATCGCTTTCCTATTTTCATACCACAAGCTTTAATTAATGAACAAATTGAATATAAAATTATCAAAGTAAAAAAGAACT
TTGCGATAGGTAAGTTGCTTAATATAAATACGAGAAGTGAGAATCGTGTTGCACCGCCATGTATATATTATGAACGTTGT
GGTGGGTGCCAACTTCAACACTTATCATACGAATCACAACTTGAAATGAAAAAGGAACAAGTGATTAATTTGTTTCAGCG
AAAAGCGCAGTTTGATAATTCTAAGATTAACGATACAGTTGGCATGACAGATCCTTGGAGATATCGAAACAAGTCCCAGA
TTCCAGTTGGTAAGAATGAACAGAATGAAGTTATTATGGGCTTTTATCGTCAAAGAAGCCATGACATTATTGACATGGAA
AGTTGTTTAATACAAGATTCACAACATCAAGAAGTGATGAATGAAGTTAAATCTATTTTAAAAGATTTAAATGTAAGTAT
TTATCAAGAACAATTGAAAAAAGGTTTAATGAGACATTTGGTTGTAAGAACAGGATATCATACAGACGAAATGATGATTA
TTTTTGTAACTAATGGTAAAAAGTGGTCACAAAAAAATGCTGTTGTTGAGAAGATATTAGATGCATTTCCTAATGTGACA
AGCATTAAACAAAACATTAATGATAGCCACTCTAATGTTATTATGGGACGTCAGTCTATAACGCTATATGGTAAAGATAC
AATTATTGATCAATTAACAGATAGTACATTTAAAATAAGTGATCAGTCATTCTACCAAATTAATTCTGAACAAACAGAGA
AATTATATAATAAAGCAATTGAGTATGCGCAATTGACAGGTAATGAAGTTGTATTAGATACCTATTGTGGTATTGGAACA
ATAGGGCTATATATGGCACCACATGCAAAACATGTATACGGTGTTGAAGTAGTACCTTCTGCAATTGAAGACGCACAAAA
AAATGCGACTATAAACCAATGCAATAATACAACTTTTGTCTGTGGGAAAGCTGAAGAAGTTATTTTACAATGGAAAGCAC
AAGGGATTAAACCAGATGTTGTAATGGTTGATCCGCCAAGAAAGGGCTGTGACGAAACGTTTATTCAGACTTTGCTTACA
TTAGAACCTAAGCGTATTGTCTATATTTCATGTAATCCCGCAACACAGCAACGTGATGCATTATTATTAGCTGAAAAATA
TCAACTTGAAGAGGTAACACCGGTAGATATGTTTCCACAAACAACACATGTTGAGACAGTGGCATTATTCAATTTGAAAT
AG

Upstream 100 bases:

>100_bases
ACAATTTAATCGAAGAATAAACAGAAGTAGTGAAATATATAATGGCAGGTTAGGAAGCGCATAATTTTGTTCCTAACCTG
TTCATTTTGGAGGTAAAATT

Downstream 100 bases:

>100_bases
CGCACATGATTTGAGATAAAATTTCGCCTTAATAAGTGAAGAAAGAAGTCGTATATTAAAATTTTATTACAGCCAATTTA
CTTTCTTGATATGAACTTTT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERC
GGCQLQHLSYESQLEMKKEQVINLFQRKAQFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWSQKNAVVEKILDAFPNVT
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGT
IGLYMAPHAKHVYGVEVVPSAIEDAQKNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLT
LEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK

Sequences:

>Translated_453_residues
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERC
GGCQLQHLSYESQLEMKKEQVINLFQRKAQFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWSQKNAVVEKILDAFPNVT
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGT
IGLYMAPHAKHVYGVEVVPSAIEDAQKNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLT
LEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>Mature_453_residues
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERC
GGCQLQHLSYESQLEMKKEQVINLFQRKAQFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWSQKNAVVEKILDAFPNVT
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGT
IGLYMAPHAKHVYGVEVVPSAIEDAQKNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLT
LEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=350, Percent_Identity=28, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI51173878, Length=350, Percent_Identity=28, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI269784680, Length=415, Percent_Identity=26.9879518072289, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI269784676, Length=415, Percent_Identity=26.9879518072289, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI20149688, Length=415, Percent_Identity=26.9879518072289, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI269784678, Length=354, Percent_Identity=28.2485875706215, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1789148, Length=457, Percent_Identity=29.9781181619256, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1787083, Length=380, Percent_Identity=25, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1790403, Length=211, Percent_Identity=27.0142180094787, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71997438, Length=161, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322909, Length=449, Percent_Identity=23.3853006681514, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24666579, Length=417, Percent_Identity=28.537170263789, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR010280 [H]

Pfam domain/function: PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 51704; Mature: 51704

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
CCCCCCCCCCCCCEEEEEECCCCEEEECCCCEECCHHHHCCCCEEEEEEEECCCCEEEEE
NINTRSENRVAPPCIYYERCGGCQLQHLSYESQLEMKKEQVINLFQRKAQFDNSKINDTV
ECCCCCCCCCCCCEEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHH
KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWSQKNAVVEKILDAFPNVT
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHH
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
HHHHHCCCCCCEEEEECCEEEEEECHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHH
EYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQKNATINQCNNTTFV
HHHHCCCCEEEEEECCCCCHHHHEECCCCCEEEEHEECCHHHHHHHHCCEEECCCCCEEE
CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
ECCHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCE
LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
EEEEHHHCCCCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
CCCCCCCCCCCCCEEEEEECCCCEEEECCCCEECCHHHHCCCCEEEEEEEECCCCEEEEE
NINTRSENRVAPPCIYYERCGGCQLQHLSYESQLEMKKEQVINLFQRKAQFDNSKINDTV
ECCCCCCCCCCCCEEEHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHH
KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWSQKNAVVEKILDAFPNVT
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCHH
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
HHHHHCCCCCCEEEEECCEEEEEECHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHH
EYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQKNATINQCNNTTFV
HHHHCCCCEEEEEECCCCCHHHHEECCCCCEEEEHEECCHHHHHHHHCCEEECCCCCEEE
CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
ECCHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCE
LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
EEEEHHHCCCCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]