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The map label for this gene is lytA [H]

Identifier: 82751424

GI number: 82751424

Start: 1844930

End: 1846375

Strand: Reverse

Name: lytA [H]

Synonym: SAB1703c

Alternate gene names: 82751424

Gene position: 1846375-1844930 (Counterclockwise)

Preceding gene: 82751425

Following gene: 82751423

Centisome position: 67.32

GC content: 41.15

Gene sequence:

>1446_bases
ATGCAAGCAAAACTAACTAAAAAAGAGTTTATAGAGTGGTTGAAAACATCTGAGGGAAAACAATATAATGCGGACGGATG
GTATGGATTTCAATGCTTTGATTATGCTAATGCTGGTTGGAAAGCTTTGTTCGGATTACTTTTAAAAGGTGTAGGTGCAA
AAGATATTCCATTCGCCAACAATTTTGACGGACTAGCTACTGTATACCAAAATACACCAGACTTCTTAGCGCAACCTGGC
GACATGGTTGTATTCGGTAGTAATTATGGTGCAGGATACGGTCATGTTGCATGGGTAATTGAAGCAACTTTAGATTATAT
CATTGTATATGAGCAGAATTGGCTCGGCGGTGGCTGGACAGACGGTGTACAACAACCTGGCTCTGGTTGGGAAAAAGTTA
CAAGACGCCAACACGCTTACGACTTCCCTATGTGGTTTATCCGTCCTAACTTCAAAAGCGAAACAGCTCCACGATCAGTA
CAATCTCCTACGCAAGCATCTAAAAAGGAAACGGCTAAGCCACAACCTAAAGCGGTAGAACTTAAAATCATCAAAGATGT
GGTTAAAGGTTATGATCTACCTAAGCGTGGTAGTAACCCTAACTTTATAGTTATTCACAACGACGCAGGAAGCAAAGGAG
CAACAGCAGAAGCATATCGTAATGGATTAGTTAACGCGCCATTATCGAGACTAGAGGCAGGTATTGCGCATAGTTACGTA
TCAGGTAACACGGTTTGGCAAGCCTTAGACGAATCGCAAGTAGGTTGGCATACAGCGAACCAAATAGGCAATAAATATGG
TTACGGTATTGAAGTGTGCCAATCAATGGGAGCAGATAATGCGACGTTTTTAAAAAATGAACAGGCGACTTTCCAAGAAT
GTGCTAGATTGTTGAAAAAATGGGGATTACCAGCAAACCGTAACACAATCCGATTACACAACGAATTCACTTCAACATCA
TGCCCACACAGAAGCTCAGTATTGCACACTGGTTTTGACCCAGTAACTCGTGGTCTATTGCCAGAAGATAAACGACTACA
ACTTAAAGACTACTTTATCAAGCAAATTAGAGCATACATGGATGGTAAAATACCGGTTGCTACTGTCTCAAATGATTCAA
GTGCTTCAAGTAATACAGTTAAGCCAGTTGCGAGTGCATGGAAACGTAATAAATATGGTACTTACTACATGGAAGAAAGT
GCTAGATTCACAAACGGCAATCAACCAATCACAGTAAGAAAAGTGGGGCCATTTTTATCTTGTCCAGTGGGTTATCAGTT
CCAACCTGGTGGATATTGTGATTATACAGAAGTGATGTTACAAGATGGCCACGTTTGGGTAGGATATACATGGGAGGGGC
AACGTTATTACTTGCCTATTAGAACATGGAATGGTTCTGCCCCGCCTAATCAGATATTAGGTGACTTATGGGGAGAAATC
AGTTAA

Upstream 100 bases:

>100_bases
GCGAAAGTACCGAAAGAGTATGACACATCACAGCCATTTACAGACGCCTCTAATGAGGTTGGTTTTGACGTGAACGAATA
TCATTATGGAGGTGGCGACA

Downstream 100 bases:

>100_bases
TATAAAATTGTGGTGAGTCTTTTCTAGGCGGGTGCATTATATGCATTCGCCTTTTTTATTTGCATTAAAAAATAATTGTG
GTATTATTTCTATATATTTT

Product: phage-related amidase

Products: NA

Alternate protein names: N-acetylmuramoyl-L-alanine amidase [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MQAKLTKKEFIEWLKTSEGKQYNADGWYGFQCFDYANAGWKALFGLLLKGVGAKDIPFANNFDGLATVYQNTPDFLAQPG
DMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWTDGVQQPGSGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSV
QSPTQASKKETAKPQPKAVELKIIKDVVKGYDLPKRGSNPNFIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
SGNTVWQALDESQVGWHTANQIGNKYGYGIEVCQSMGADNATFLKNEQATFQECARLLKKWGLPANRNTIRLHNEFTSTS
CPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYMDGKIPVATVSNDSSASSNTVKPVASAWKRNKYGTYYMEES
ARFTNGNQPITVRKVGPFLSCPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
S

Sequences:

>Translated_481_residues
MQAKLTKKEFIEWLKTSEGKQYNADGWYGFQCFDYANAGWKALFGLLLKGVGAKDIPFANNFDGLATVYQNTPDFLAQPG
DMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWTDGVQQPGSGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSV
QSPTQASKKETAKPQPKAVELKIIKDVVKGYDLPKRGSNPNFIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
SGNTVWQALDESQVGWHTANQIGNKYGYGIEVCQSMGADNATFLKNEQATFQECARLLKKWGLPANRNTIRLHNEFTSTS
CPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYMDGKIPVATVSNDSSASSNTVKPVASAWKRNKYGTYYMEES
ARFTNGNQPITVRKVGPFLSCPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
S
>Mature_481_residues
MQAKLTKKEFIEWLKTSEGKQYNADGWYGFQCFDYANAGWKALFGLLLKGVGAKDIPFANNFDGLATVYQNTPDFLAQPG
DMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWTDGVQQPGSGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSV
QSPTQASKKETAKPQPKAVELKIIKDVVKGYDLPKRGSNPNFIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
SGNTVWQALDESQVGWHTANQIGNKYGYGIEVCQSMGADNATFLKNEQATFQECARLLKKWGLPANRNTIRLHNEFTSTS
CPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYMDGKIPVATVSNDSSASSNTVKPVASAWKRNKYGTYYMEES
ARFTNGNQPITVRKVGPFLSCPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
S

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 peptidase C51 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR007921
- InterPro:   IPR003646
- InterPro:   IPR013667 [H]

Pfam domain/function: PF01510 Amidase_2; PF05257 CHAP; PF08460 SH3_5 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 53766; Mature: 53766

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50911 CHAP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAKLTKKEFIEWLKTSEGKQYNADGWYGFQCFDYANAGWKALFGLLLKGVGAKDIPFAN
CCCCCCHHHHHHHHHCCCCCEECCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
NFDGLATVYQNTPDFLAQPGDMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWT
CCCCHHHHHCCCHHHHCCCCCEEEECCCCCCCCCHHHHHEEEEEEEEEEEECCCCCCCCC
DGVQQPGSGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSVQSPTQASKKETAKPQPKAVE
CCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEH
LKIIKDVVKGYDLPKRGSNPNFIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
HHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHC
SGNTVWQALDESQVGWHTANQIGNKYGYGIEVCQSMGADNATFLKNEQATFQECARLLKK
CCCHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
WGLPANRNTIRLHNEFTSTSCPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYM
CCCCCCCCEEEEECCCCCCCCCCCCCCEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHH
DGKIPVATVSNDSSASSNTVKPVASAWKRNKYGTYYMEESARFTNGNQPITVRKVGPFLS
CCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCEE
CPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
CCCCCEECCCCCCCHHHHHEECCCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHCCC
S
C
>Mature Secondary Structure
MQAKLTKKEFIEWLKTSEGKQYNADGWYGFQCFDYANAGWKALFGLLLKGVGAKDIPFAN
CCCCCCHHHHHHHHHCCCCCEECCCCEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
NFDGLATVYQNTPDFLAQPGDMVVFGSNYGAGYGHVAWVIEATLDYIIVYEQNWLGGGWT
CCCCHHHHHCCCHHHHCCCCCEEEECCCCCCCCCHHHHHEEEEEEEEEEEECCCCCCCCC
DGVQQPGSGWEKVTRRQHAYDFPMWFIRPNFKSETAPRSVQSPTQASKKETAKPQPKAVE
CCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEH
LKIIKDVVKGYDLPKRGSNPNFIVIHNDAGSKGATAEAYRNGLVNAPLSRLEAGIAHSYV
HHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHC
SGNTVWQALDESQVGWHTANQIGNKYGYGIEVCQSMGADNATFLKNEQATFQECARLLKK
CCCHHHHHHCCCCCCCHHHHHHCCCCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHH
WGLPANRNTIRLHNEFTSTSCPHRSSVLHTGFDPVTRGLLPEDKRLQLKDYFIKQIRAYM
CCCCCCCCEEEEECCCCCCCCCCCCCCEECCCCHHHHCCCCCCCCHHHHHHHHHHHHHHH
DGKIPVATVSNDSSASSNTVKPVASAWKRNKYGTYYMEESARFTNGNQPITVRKVGPFLS
CCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEECCCCEE
CPVGYQFQPGGYCDYTEVMLQDGHVWVGYTWEGQRYYLPIRTWNGSAPPNQILGDLWGEI
CCCCCEECCCCCCCHHHHHEECCCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1677905 [H]