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The map label for this gene is aroA

Identifier: 82751326

GI number: 82751326

Start: 1733582

End: 1734673

Strand: Reverse

Name: aroA

Synonym: SAB1597c

Alternate gene names: 82751326

Gene position: 1734673-1733582 (Counterclockwise)

Preceding gene: 82751327

Following gene: 82751325

Centisome position: 63.25

GC content: 33.7

Gene sequence:

>1092_bases
ATGAGTAATAAATTAGAATCATACAGAAGTGATATTGTATCACTGAATCATCAAATTTTAGATTTATTATCTAAACGTGG
TGAACTAGCACAAAAAATTGGGGAAGAAAAATTAAAACAAGGTACACGTATCTATGATCCACAACGCGAAAAAGAAATGC
TTAACGACTTAATTGATAGCAACAAAGGACCATTTAACGATAATACAATTAAGCAATTATTTAAAGAAATTTTTAAAGCC
TCTACAGATTTACAAAAATCTGAAAATGAAAAACACTTATACGTATCTCGTAAGTTGAAACCTGAGGATACGATTGTAAC
ATTTGATAATGGGGGTATTATTGGAGATGGCAACAAATCATTTGTATTTGGACCATGCTCAGTTGAATCATTTGAACAAG
TAGAAGCGGTAGCTAAAAATTTACATGCCAAAGGTGAAAAGTTTATTCGTGGCGGTGCTTTTAAACCACGTACATCGCCT
TATGACTTCCAAGGCCTAGGTGTTGAAGGACTTAAAATACTTAAACAGATTAAAGATAAATACGATTTAAATGTAGTTAG
TGAAATTGTAAATTCTAATGATTTTGAAGTAGCCGACGAATATTTAGATGTATTCCAAATTGGTGCACGTAATATGCAAA
ACTTTGAGTTATTAAAAGAAGCTGGGCGTACGAAAAAGCCTATTCTATTAAAACGTGGTCTATCTGCTACAATTGAAGAG
TTTGTTTATGCAGCTGAATACATTGCTTCACAAGGTAATCAAAACATTATTTTATGTGAACGCGGAATCCGAACTTATGA
AAAGGCGACACGTAACACTTTAGATATTTCAGCAGTACCAATTTTAAAACAAGGTACACACTTACCAGTCATGGTAGATG
TCACGCATAGTACAGGTCGTAAAGATATCATGTTACCAACTGCGAAAGCAGCATTAGCAGTAGGTGCTGATGGTGTTATG
GCTGAGGTGCATCCAGATCCATCTGTTGCACTTAGTGATGCGGGTCAACAAATGAATTTAGATGAATTCCAAGCATTTTA
TGATGAATTAAAGCCTTTAGCTGATTTATATAACGCTAAAAAGTTAAAATAA

Upstream 100 bases:

>100_bases
GTTGAACTATACATATGATATTGTTAGAATATTTTTTAACATTATATTTTATTGCTTTAAAGTGGAATATACTTGAAATA
ATTCGTAGAGGTGAGTAAGG

Downstream 100 bases:

>100_bases
TATTCCAAGGAAACTATAGACTACTTAACTAATATGTCATGTTGAAGTAGATATTATCTTTGAATTGACAATTTTAAACT
AGTAGCCATTCTAAGAGTAT

Product: bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase

Products: NA

Alternate protein names: Phospho-2-dehydro-3-deoxyheptonate aldolase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; Chorismate mutase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSNKLESYRSDIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDSNKGPFNDNTIKQLFKEIFKA
STDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKSFVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSP
YDFQGLGVEGLKILKQIKDKYDLNVVSEIVNSNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEE
FVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGRKDIMLPTAKAALAVGADGVM
AEVHPDPSVALSDAGQQMNLDEFQAFYDELKPLADLYNAKKLK

Sequences:

>Translated_363_residues
MSNKLESYRSDIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDSNKGPFNDNTIKQLFKEIFKA
STDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKSFVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSP
YDFQGLGVEGLKILKQIKDKYDLNVVSEIVNSNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEE
FVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGRKDIMLPTAKAALAVGADGVM
AEVHPDPSVALSDAGQQMNLDEFQAFYDELKPLADLYNAKKLK
>Mature_362_residues
SNKLESYRSDIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDSNKGPFNDNTIKQLFKEIFKAS
TDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKSFVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSPY
DFQGLGVEGLKILKQIKDKYDLNVVSEIVNSNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEEF
VYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGRKDIMLPTAKAALAVGADGVMA
EVHPDPSVALSDAGQQMNLDEFQAFYDELKPLADLYNAKKLK

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 chorismate mutase domain [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=214, Percent_Identity=26.1682242990654, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR002701
- InterPro:   IPR010954
- InterPro:   IPR020822
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF01817 CM_2; PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54; =5.4.99.5 [H]

Molecular weight: Translated: 40594; Mature: 40463

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKLESYRSDIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
NKGPFNDNTIKQLFKEIFKASTDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKS
CCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCCCEEEECCCCEEECCCCC
FVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSPYDFQGLGVEGLKILKQIKDK
EEECCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YDLNVVSEIVNSNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCHHHHHH
FVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGR
HHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEECCHHHCCCCCCEEEEECCCCCC
KDIMLPTAKAALAVGADGVMAEVHPDPSVALSDAGQQMNLDEFQAFYDELKPLADLYNAK
CCEECCCHHHHHHCCCCCCEEEECCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
KLK
CCC
>Mature Secondary Structure 
SNKLESYRSDIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRIYDPQREKEMLNDLIDS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
NKGPFNDNTIKQLFKEIFKASTDLQKSENEKHLYVSRKLKPEDTIVTFDNGGIIGDGNKS
CCCCCCCHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCCCCEEEECCCCEEECCCCC
FVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSPYDFQGLGVEGLKILKQIKDK
EEECCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
YDLNVVSEIVNSNDFEVADEYLDVFQIGARNMQNFELLKEAGRTKKPILLKRGLSATIEE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCHHHHHH
FVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDISAVPILKQGTHLPVMVDVTHSTGR
HHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCCEEECCHHHCCCCCCEEEEECCCCCC
KDIMLPTAKAALAVGADGVMAEVHPDPSVALSDAGQQMNLDEFQAFYDELKPLADLYNAK
CCEECCCHHHHHHCCCCCCEEEECCCCCEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
KLK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7496534; 9387221; 9384377 [H]