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The map label for this gene is clpX

Identifier: 82751263

GI number: 82751263

Start: 1653764

End: 1655026

Strand: Reverse

Name: clpX

Synonym: SAB1534c

Alternate gene names: 82751263

Gene position: 1655026-1653764 (Counterclockwise)

Preceding gene: 82751264

Following gene: 82751262

Centisome position: 60.35

GC content: 34.13

Gene sequence:

>1263_bases
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATTACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTGGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCCTTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGATGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCCATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAAACGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGTAATTTAATTAATAATAGTAAAACATCAGCTTAA

Upstream 100 bases:

>100_bases
GTATCTGCTACTATTCTTTAAGCAAAAAGTTTGTATGTTAATATGTTGCATTGTAATATCCAATCTAGTATAGTCTTTAA
CGAATAGGGGTGTAAAAAGA

Downstream 100 bases:

>100_bases
TCATTGATGTGTTATAAAAGTGAAAAGCTCCAATCAAAGTTGACGCTCAAATAGTTTAACTTTGATCGGAGCTTTTTTAT
AATGTATACCCAAAGGTTCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEDVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEETLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Sequences:

>Translated_420_residues
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEDVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEETLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA
>Mature_420_residues
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEDVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEETLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=329, Percent_Identity=46.2006079027356, Blast_Score=298, Evalue=7e-81,
Organism=Escherichia coli, GI1786642, Length=400, Percent_Identity=61, Blast_Score=496, Evalue=1e-141,
Organism=Escherichia coli, GI1790366, Length=105, Percent_Identity=45.7142857142857, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71982905, Length=338, Percent_Identity=42.0118343195266, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71982908, Length=338, Percent_Identity=42.0118343195266, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=408, Percent_Identity=37.9901960784314, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=252, Percent_Identity=41.2698412698413, Blast_Score=181, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6319704, Length=446, Percent_Identity=39.237668161435, Blast_Score=268, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24648289, Length=317, Percent_Identity=46.6876971608833, Blast_Score=301, Evalue=7e-82,
Organism=Drosophila melanogaster, GI24648291, Length=317, Percent_Identity=46.6876971608833, Blast_Score=301, Evalue=7e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46280; Mature: 46280

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITE
CCCCCCCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTG
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCC
SGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIY
CCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEE
VDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
HHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCE
ILFILGGAFDGIEDVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIG
EEEEECCCCCCHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCHHHHC
RVPIVANLETLDVTALKNILTQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERK
CCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
TGARGLRSIIEETLIDIMFDVPSNENVTKVVITAQTINEETEPELYDAEGNLINNSKTSA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCEECCCCCEECCCCCCC
>Mature Secondary Structure
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITE
CCCCCCCCCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTG
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEECCCC
SGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIY
CCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEE
VDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
HHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCE
ILFILGGAFDGIEDVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIG
EEEEECCCCCCHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCHHHHC
RVPIVANLETLDVTALKNILTQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERK
CCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
TGARGLRSIIEETLIDIMFDVPSNENVTKVVITAQTINEETEPELYDAEGNLINNSKTSA
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA