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The map label for this gene is kipI [H]

Identifier: 82751209

GI number: 82751209

Start: 1594926

End: 1595684

Strand: Reverse

Name: kipI [H]

Synonym: SAB1480c

Alternate gene names: 82751209

Gene position: 1595684-1594926 (Counterclockwise)

Preceding gene: 82751210

Following gene: 82751208

Centisome position: 58.18

GC content: 33.2

Gene sequence:

>759_bases
TTGCAATACAAAGGGGGATTTAGAGTGGATGTAAGATTTATTAACGAGCAGACAATTATGATTTATTTTGAAAATAAAAT
ATCCGAAGAGACATATCGAAATGTCACAGCAATGGTACGGTGGATACGAGAAAAAGAAATATTAGAAATTCAAGATATTG
TCCCTTCGTATCGAGCAGTTCTAATATATTTTGATGAACAATCTATAACACCTTCTAAATTAATTGAAAATTTAGAACTT
AACAAATTTAATGAAAAAAATGTTCATGCTGTGAATCAAACCAATCGTATTATTAAAATACCTGTTCAATATGGTGGTAC
ATATGGACCTGATATTGAAGAGGTAGCAAAGCATAATCGAATAACTGTTGAGCAAGTTATTGAAAAACATACAAATAAAC
CTTATTTAATATATATGCTAGGATTTATGCCTGGATTTCCATACTTAGGCGGACTTGATGAACAACTACATACACCTAGA
CGTAATCAGCCAAGGTTAAAAATTCATGCAGGTTCTGTAGGTATTGCGAATAATCAAACAGGACTATATCCATCAGATTC
TCCTGGCGGATGGCAAATTATTGGACGCACACCGTTAAAAGTATTTAGCAGCGAGCGTGAACCAATGTCAATGTATGAAG
CAGGAGAATGGATACAATTTTATGCAATAGATGAACAGGAATTTATACAAATCGAAAGAGATATATCAGATGGCAACTTT
AATGTTGATGACTGGGTGGTGATCGAAAATGTCAATTAA

Upstream 100 bases:

>100_bases
ACAAATTGATTATGATTTGTTATTGTATGCGATTTGAATTACTTATTAAACAACTTGTGCTTCTCAATGATACAATGAAA
AGGTATTCAATACTGGTTTA

Downstream 100 bases:

>100_bases
GATTTTACAACCAGGTCTCTTTTCAACGGTACAAGATCTAGGAAGAAATGGTTATGAACATATTGGATTTTCAGGCGCAG
GTGCCATGGATCAATTTAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Sporulation inhibitor kipI [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MQYKGGFRVDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAVLIYFDEQSITPSKLIENLEL
NKFNEKNVHAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNRITVEQVIEKHTNKPYLIYMLGFMPGFPYLGGLDEQLHTPR
RNQPRLKIHAGSVGIANNQTGLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQEFIQIERDISDGNF
NVDDWVVIENVN

Sequences:

>Translated_252_residues
MQYKGGFRVDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAVLIYFDEQSITPSKLIENLEL
NKFNEKNVHAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNRITVEQVIEKHTNKPYLIYMLGFMPGFPYLGGLDEQLHTPR
RNQPRLKIHAGSVGIANNQTGLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQEFIQIERDISDGNF
NVDDWVVIENVN
>Mature_252_residues
MQYKGGFRVDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAVLIYFDEQSITPSKLIENLEL
NKFNEKNVHAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNRITVEQVIEKHTNKPYLIYMLGFMPGFPYLGGLDEQLHTPR
RNQPRLKIHAGSVGIANNQTGLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQEFIQIERDISDGNF
NVDDWVVIENVN

Specific function: Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786929, Length=213, Percent_Identity=35.6807511737089, Blast_Score=147, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003833
- InterPro:   IPR020899
- InterPro:   IPR010016
- InterPro:   IPR002130 [H]

Pfam domain/function: PF02682 AHS1 [H]

EC number: NA

Molecular weight: Translated: 29340; Mature: 29340

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYKGGFRVDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAV
CCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LIYFDEQSITPSKLIENLELNKFNEKNVHAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNR
EEEECCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHCCC
ITVEQVIEKHTNKPYLIYMLGFMPGFPYLGGLDEQLHTPRRNQPRLKIHAGSVGIANNQT
EEHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCCEEEEEECCEEECCCCC
GLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQEFIQIERDISDGNF
CCCCCCCCCCEEEEECCCHHHHCCCCCCHHHHCCCCEEEEEEECHHHEEEEEECCCCCCC
NVDDWVVIENVN
CCCCEEEEEECC
>Mature Secondary Structure
MQYKGGFRVDVRFINEQTIMIYFENKISEETYRNVTAMVRWIREKEILEIQDIVPSYRAV
CCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LIYFDEQSITPSKLIENLELNKFNEKNVHAVNQTNRIIKIPVQYGGTYGPDIEEVAKHNR
EEEECCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCHHHHHHCCC
ITVEQVIEKHTNKPYLIYMLGFMPGFPYLGGLDEQLHTPRRNQPRLKIHAGSVGIANNQT
EEHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCCEEEEEECCEEECCCCC
GLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQEFIQIERDISDGNF
CCCCCCCCCCEEEEECCCHHHHCCCCCCHHHHCCCCEEEEEEECHHHEEEEEECCCCCCC
NVDDWVVIENVN
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]