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The map label for this gene is trpB

Identifier: 82750963

GI number: 82750963

Start: 1342583

End: 1343797

Strand: Direct

Name: trpB

Synonym: SAB1227

Alternate gene names: 82750963

Gene position: 1342583-1343797 (Clockwise)

Preceding gene: 82750962

Following gene: 82750964

Centisome position: 48.95

GC content: 38.02

Gene sequence:

>1215_bases
ATGAATAAACAAATACAAACAGAAGCAGATGAATTAGGTTTCTTTGGTGAATATGGAGGGCAATATGTTCCAGAAACATT
AATGCCAGCAATTATTGAGTTGAAAAAAGCTTATAAAGAGGCAAAAGCAGACCCAGAGTTTCAAAGAGAACTTGAATACT
ATTTATCAGAGTATGTAGGACGCACGACGCCACTTACATATGCTGCATCATATACTGAAAGCCTAGGAGGCGCTAAAATA
TATTTAAAACGAGAGGATCTAAATCATACAGGCGCCCATAAAATTAATAATGCCTTAGGTCAAGCGTTGCTCGCTAAAAG
AATGGGCAAGAAGAAGCTTGTTGCTGAAACAGGTGCGGGTCAACATGGTGTAGCTAGTGCTACGGTTGCTGCATTATTTG
ATATGGAACTTGTTGTCTTTATGGGAAGTGAAGATATTAAAAGACAACAACTTAATGTATTTAGAATGGAATTACTTGGT
GCAAAGGTTGTGGCAGTTGAAGATGGTCAAGGGACTTTATCGGATGCAGTTAATAAAGCATTGCAATATTGGGTAAGTCA
TGTAGATGACACACATTATTTATTAGGTTCTGCATTAGGTCCAGACCCATTCCCAACGATTGTTAGAGATTTTCAGAGTG
TGATTGGTAAAGAAATAAAATCACAGATATTGAAGAAAGAAGGTCGACTTCCGGATGCAATTGTAGCATGTATCGGTGGT
GGCTCAAATGCAATCGGTACATTTTATCCATTTATTAAAGATGATGTTGCGTTATACGGTGTTGAAGCCGCAGGTCAAGG
CGAGGATACTGATAAACATGCACTTGCAATTGGCAAAGGATCACCTGGCGTATTACATGGTACTAAAATGTATTTAATTC
AAGATGAAGGTGGGCAAGTGCAACTAGCACATTCTATTTCAGCAGGACTTGATTATCCTGGTATTGGACCAGAACATTCT
TATTACCACGACATTGGTAGAGTAACTTTTGAAAATGCAAGTGATACACAAGCAATGAATGCTTTAATCAACTTTACAAA
ACATGAAGGTACTATACCTGCAATTGAAAGTGCACATGCACTGAGTTATGTTGAAAGACTAGCGCCTACGATGTCGAAAG
AAGATATTATTGTAGTAACTATTTCTGGACGTGGCGATAAAGATATGGAAACAATTAGACAATATATGGCAGAGCGAGGT
CTTGCAAATGACTAA

Upstream 100 bases:

>100_bases
CATCAAGGTTTTGATCTTGCATCAGGTATAGAAGTAAATGGGCGAAAAGATATAGAAAAAATGACAGCAATTGTAAATAT
TGTGAAAGGAGATAGAGAAA

Downstream 100 bases:

>100_bases
ATTATTTATACCTTATATTATGGGCGATAAAGATTTGATTGAAAATGCAACATTGTTGAGTGAAAATGGTGCAGATATAA
TTGAAATTGGTGTACCTTTC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRTTPLTYAASYTESLGGAKI
YLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
AKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHS
YYHDIGRVTFENASDTQAMNALINFTKHEGTIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERG
LAND

Sequences:

>Translated_404_residues
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRTTPLTYAASYTESLGGAKI
YLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
AKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHS
YYHDIGRVTFENASDTQAMNALINFTKHEGTIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERG
LAND
>Mature_404_residues
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRTTPLTYAASYTESLGGAKI
YLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
AKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHS
YYHDIGRVTFENASDTQAMNALINFTKHEGTIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERG
LAND

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=389, Percent_Identity=49.6143958868895, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321412, Length=388, Percent_Identity=53.6082474226804, Blast_Score=428, Evalue=1e-120,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43911; Mature: 43911

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVG
CCCCCCCCHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RTTPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAG
CCCCCEEEHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
QHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEDGQGTLSDAVNKA
CCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
LQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
HHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECC
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQV
CCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCCCEEECEEEEEEECCCCEE
QLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGTIPAIESAHA
EEEEHHHCCCCCCCCCCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
LSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERGLAND
HHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVG
CCCCCCCCHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RTTPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAG
CCCCCEEEHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
QHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEDGQGTLSDAVNKA
CCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
LQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
HHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECC
GSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQV
CCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCCCEEECEEEEEEECCCCEE
QLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGTIPAIESAHA
EEEEHHHCCCCCCCCCCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHH
LSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERGLAND
HHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA