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The map label for this gene is sbcD [H]

Identifier: 82750939

GI number: 82750939

Start: 1307899

End: 1309020

Strand: Direct

Name: sbcD [H]

Synonym: SAB1203

Alternate gene names: 82750939

Gene position: 1307899-1309020 (Clockwise)

Preceding gene: 82750938

Following gene: 82750940

Centisome position: 47.69

GC content: 31.11

Gene sequence:

>1122_bases
ATGAAAATTATACATACAGCAGACTGGCACTTAGGGAAAATATTAAATGGCAAACAGCTTTTAGAAGATCAAACGTATAT
TTTAGATATGTTCGTAGAAAAAATGAAAGAAGAAGAACCTGATATCATTGTGATAGCTGGAGATTTATATGACACAACAT
ATCCAAGTAAAGATGCAATCATGTTATTAGAACAAGCGATTGGAAAGCTAAATTTAGAACTGCGTATACCAATAATTATG
ATTAGCGGAAATCACGATGGTAAAGAGAGATTAAACTATGGGGCGAGTTGGTTTGAACATAATCAGTTATTTATAAGAAC
AGATTTTACATCGATTAATTCGCCAATAGAGATAAATGGGGTTAATTTTTATACACTCCCTTATGCTACTGTGAGCGAAA
TGAAACACTATTTTGAAGATGACACCATTGAAACGCATCAACAGGGAATTACGCGCTGTATTGAAACAATAGCACCGGCA
ATTGATGAAGTTGCCGTCAATATTTTAATTAGTCATCTGACTGTTCAAGGTGGAAAGACATCTGATTCTGAAAGACCATT
AACTATTGGAACGGTTGAATCAGTTCAGAAAGGTGTTTTTGATATATTTGATTATGTCATGCTAGGTCACTTGCATCATC
CATTTAGTATAGAAGACGACAAAATTAAATATAGTGGCTCCTTATTGCAGTATTCATTTTCGGAAGCGGGTCAAGCTAAA
GGGTATAGACGTGTAACAATTAACGATGGCATTATTAACGATGTATTTATTCCTCTTAAGTCGCTTAGACAATTGGAAAT
TATCTCGGGCGAATATAATGATGTTATTAATGAAAAAGTTCATGTGAAAAATAAAGATAATTATTTACATTTTAAACTTA
AAAATATGTCTCATATTACTGATCCAATGATGAGTTTAAAACAAATTTATCCTAATACTTTAGCGCTGACGAATGAAACT
TTTAATTACAATGAAGAAAATAATACTATAGAAATAAGTGAAAAAGATGACATGTCAATCATCGAAATGTTTTATAACCA
TATAACTGATAAAAAATTATCGGATATCCAATCTAAAAAGATAAAAAATATTTTAGAAAACGAATTGAGAAAGGAGGATT
AA

Upstream 100 bases:

>100_bases
CGACTTTTAAATCAGTCAATGAGTGGTTTTAATTTTACTTGAAAAGGTGAAATGTTTATAATAAAATAAAAGAGAACAAA
TGTTCTATATGGAGGCAGTA

Downstream 100 bases:

>100_bases
TGAATGAAACCATTACATTTAAAGTTGAATAATTTCGGCCCCTTTTTAAAAGAAGAAATTGATTTTTCTAAAATTGATAA
TAATGAATTGTTTTTAATAA

Product: exonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKIIHTADWHLGKILNGKQLLEDQTYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIM
ISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPA
IDEVAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
GYRRVTINDGIINDVFIPLKSLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNET
FNYNEENNTIEISEKDDMSIIEMFYNHITDKKLSDIQSKKIKNILENELRKED

Sequences:

>Translated_373_residues
MKIIHTADWHLGKILNGKQLLEDQTYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIM
ISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPA
IDEVAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
GYRRVTINDGIINDVFIPLKSLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNET
FNYNEENNTIEISEKDDMSIIEMFYNHITDKKLSDIQSKKIKNILENELRKED
>Mature_373_residues
MKIIHTADWHLGKILNGKQLLEDQTYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIM
ISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPA
IDEVAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
GYRRVTINDGIINDVFIPLKSLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNET
FNYNEENNTIEISEKDDMSIIEMFYNHITDKKLSDIQSKKIKNILENELRKED

Specific function: SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand

COG id: COG0420

COG function: function code L; DNA repair exonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sbcD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR004593 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: NA

Molecular weight: Translated: 42915; Mature: 42915

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIHTADWHLGKILNGKQLLEDQTYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAI
CCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHH
MLLEQAIGKLNLELRIPIIMISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEING
HHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHCCCCEEECCEEEEEECCCCCCCCEEECC
VNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPAIDEVAVNILISHLTVQGGKT
EEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
SDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
CCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEHHHHHCCC
GYRRVTINDGIINDVFIPLKSLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHIT
CEEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHCCCEEEEECCCCEEEEEECCCHHHH
DPMMSLKQIYPNTLALTNETFNYNEENNTIEISEKDDMSIIEMFYNHITDKKLSDIQSKK
HHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHH
IKNILENELRKED
HHHHHHHHHCCCC
>Mature Secondary Structure
MKIIHTADWHLGKILNGKQLLEDQTYILDMFVEKMKEEEPDIIVIAGDLYDTTYPSKDAI
CCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHH
MLLEQAIGKLNLELRIPIIMISGNHDGKERLNYGASWFEHNQLFIRTDFTSINSPIEING
HHHHHHHHHCCEEEEEEEEEEECCCCCHHHHHCCCCEEECCEEEEEECCCCCCCCEEECC
VNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPAIDEVAVNILISHLTVQGGKT
EEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
SDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIEDDKIKYSGSLLQYSFSEAGQAK
CCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEEEHHHHHCCC
GYRRVTINDGIINDVFIPLKSLRQLEIISGEYNDVINEKVHVKNKDNYLHFKLKNMSHIT
CEEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHCCCEEEEECCCCEEEEEECCCHHHH
DPMMSLKQIYPNTLALTNETFNYNEENNTIEISEKDDMSIIEMFYNHITDKKLSDIQSKK
HHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHH
IKNILENELRKED
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA