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The map label for this gene is fabD

Identifier: 82750834

GI number: 82750834

Start: 1181415

End: 1182341

Strand: Direct

Name: fabD

Synonym: SAB1094

Alternate gene names: 82750834

Gene position: 1181415-1182341 (Clockwise)

Preceding gene: 82750833

Following gene: 82750835

Centisome position: 43.08

GC content: 33.98

Gene sequence:

>927_bases
ATGAGTAAAACAGCAATTATTTTTCCGGGACAAGGTGCCCAAAAAGTTGGTATGGCACAAGATTTATATAACAACAACGA
TCAAGCAACTGAAATTTTAACTTCAGCAGCAAACACGTTAGACTTTGATATTTTAGAGACAATGTTTACTGACGAAGACG
GCAAATTGGGTGAAACTGAAAACACGCAACCAGCTTTATTGACGCATAGTTCGGCATTATTAGCAGCACTAAAAAATTTG
AATCCCGATTTTACTATGGGGCATAGTTTAGGTGAATATTCAAGTTTAGTTGCAGCTGACGTATTATCATTTGAAGATGC
AGTTAAAATTGTTAGAAAACGTGGTCAATTAATGGCGCAAGCATTTCCTACTGGTGTAGGAAGCATGGCTGCAGTATTGG
GCTTAGATTTTGATAAAGTCAATGAAATTTGTAAGTCATTATCATCTGATGACCAAATAATTGAACCAGCAAACATTAAT
TGCCCAGGTCAAATTGTTGTTTCAGGTCACAAAGCTTTAATTGATGAGCTAGTAGAAAAAGGTAAATCATTAGGTGCAAA
ACGTGTCATGCCTTTAACAGTATCTGGCCCATTCCATTCATCGCTAATGAAAGTGATTGAAGAAGATTTTTCAAGTTATA
TTAATCAATTTGAATGGCGTGATGCTAAGTTTCCTGTAGTTCAAAATGTAAATGCGCAAGGTGAAACTGACAAAGAAGTA
ATTAAATCTAATATGGTCAAACAATTATATTCACCAGTACAATTCATTAACTCAACAGAATGGCTAATAGACCAAGGTGT
TGATCATTTTATTGAAATTGGTCCTGGAAAAGTTTTATCTGGCTTAATTAAAAAAATAAATAGAGATGTTAAGTTAACAT
CAATTCAAACTTTAGAAGATGTGAAAGGATGGAATGAAAATGACTAA

Upstream 100 bases:

>100_bases
AGTTCAAATGCTAAAGCTTTTTATTCTGCAATTAGACAAGCGAAAATCGCAGGAGAGCAAAATATTGTACAAACAATGAA
AGAGACTGTAGGTGAATCAA

Downstream 100 bases:

>100_bases
GAGTGCTTTAGTAACAGGTGCATCAAGAGGAATTGGACGTAGTATTGCGTTACAATTAGCAGAAGAAGGATATAATGTAG
CAGTAAACTATGCAGGCAGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSKTAIIFPGQGAQKVGMAQDLYNNNDQATEILTSAANTLDFDILETMFTDEDGKLGETENTQPALLTHSSALLAALKNL
NPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVNEICKSLSSDDQIIEPANIN
CPGQIVVSGHKALIDELVEKGKSLGAKRVMPLTVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEV
IKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND

Sequences:

>Translated_308_residues
MSKTAIIFPGQGAQKVGMAQDLYNNNDQATEILTSAANTLDFDILETMFTDEDGKLGETENTQPALLTHSSALLAALKNL
NPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVNEICKSLSSDDQIIEPANIN
CPGQIVVSGHKALIDELVEKGKSLGAKRVMPLTVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEV
IKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND
>Mature_307_residues
SKTAIIFPGQGAQKVGMAQDLYNNNDQATEILTSAANTLDFDILETMFTDEDGKLGETENTQPALLTHSSALLAALKNLN
PDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVNEICKSLSSDDQIIEPANINC
PGQIVVSGHKALIDELVEKGKSLGAKRVMPLTVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEVI
KSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLEDVKGWNEND

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=323, Percent_Identity=28.7925696594427, Blast_Score=127, Evalue=1e-29,
Organism=Escherichia coli, GI1787334, Length=289, Percent_Identity=40.4844290657439, Blast_Score=222, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=28.8659793814433, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=311, Percent_Identity=25.08038585209, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=31.2292358803987, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33667; Mature: 33535

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTAIIFPGQGAQKVGMAQDLYNNNDQATEILTSAANTLDFDILETMFTDEDGKLGETE
CCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQ
CCCCHHEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFPTGVGSMAAVLGLDFDKVNEICKSLSSDDQIIEPANINCPGQIVVSGHKALIDELVEK
HHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCHHHHHHHHHHH
GKSLGAKRVMPLTVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEV
HHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHH
IKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLED
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHHHH
VKGWNEND
HCCCCCCC
>Mature Secondary Structure 
SKTAIIFPGQGAQKVGMAQDLYNNNDQATEILTSAANTLDFDILETMFTDEDGKLGETE
CCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVLSFEDAVKIVRKRGQLMAQ
CCCCHHEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFPTGVGSMAAVLGLDFDKVNEICKSLSSDDQIIEPANINCPGQIVVSGHKALIDELVEK
HHCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEECCCCCCCCCEEEECCHHHHHHHHHHH
GKSLGAKRVMPLTVSGPFHSSLMKVIEEDFSSYINQFEWRDAKFPVVQNVNAQGETDKEV
HHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCHHHH
IKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPGKVLSGLIKKINRDVKLTSIQTLED
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCCHHHHHHHHHHHCCCCEEHHHHHHHH
VKGWNEND
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA