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The map label for this gene is pyrR

Identifier: 82750803

GI number: 82750803

Start: 1145186

End: 1145713

Strand: Direct

Name: pyrR

Synonym: SAB1062

Alternate gene names: 82750803

Gene position: 1145186-1145713 (Clockwise)

Preceding gene: 82750802

Following gene: 82750804

Centisome position: 41.76

GC content: 34.09

Gene sequence:

>528_bases
ATGTCTGAACGTATCATAATGGATGATGCCGCAATACAACGTACAGTAACGAGAATCGCTCATGAAATTTTGGAGTATAA
CAAAGGTACTGATAATTTAATTCTTTTAGGTATCAAAACAAGAGGTGAATATTTAGCGAATCGTATACAAGATAAAATTC
ATCAAATTGAGCAACAACGTATACCTACAGGAACAATTGATATTACATACTTTAGAGATGATATAGAGCACATGTCATCA
CTTACGACAAAAGACGCAATAGACATCGACACAGATATTACAGATAAAGTAGTCATCATTATTGACGATGTGCTGTATAC
TGGTCGAACGGTTCGTGCTTCACTTGATGCTATTTTGCTAAATGCTAGACCTATTAAAATTGGTTTAGCTGTTTTGGTTG
ATCGAGGACATCGTGAGTTACCGATTCGAGCAGATTTTGTTGGTAAAAATATACCTACTTCTAAAGAGGAAACGGTAAGT
GTCTATTTAGAAGAAATGGATCAAAGAAATGCAGTTATAATTAAATAA

Upstream 100 bases:

>100_bases
ACGATTCTTCTATGTAAAAAGGATGATTGTATATACTAAACCTCATGTCGATATTAAAGACATGAGGTTTTTTGTTTCTA
AATTTTGAAAGGTTGAGAAT

Downstream 100 bases:

>100_bases
TACCCCTTTTAATTCAGTACGAGAGACTGAAAAAGGTGGGGGAGTTGAATGATAAATAAGTTTTCATATGCTTGTTTATC
TAATAATACCCTCATGTTCG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSS
LTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILLNARPIKIGLAVLVDRGHRELPIRADFVGKNIPTSKEETVS
VYLEEMDQRNAVIIK

Sequences:

>Translated_175_residues
MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSS
LTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILLNARPIKIGLAVLVDRGHRELPIRADFVGKNIPTSKEETVS
VYLEEMDQRNAVIIK
>Mature_174_residues
SERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSSL
TTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILLNARPIKIGLAVLVDRGHRELPIRADFVGKNIPTSKEETVSV
YLEEMDQRNAVIIK

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 19883; Mature: 19752

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQR
CCCEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHC
IPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILL
CCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHHCCCCHHHHHEEEEE
NARPIKIGLAVLVDRGHRELPIRADFVGKNIPTSKEETVSVYLEEMDQRNAVIIK
CCCCCEEEEEEEEECCCCCCCEEHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
SERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEYLANRIQDKIHQIEQQR
CCEEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHC
IPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVIIIDDVLYTGRTVRASLDAILL
CCCCEEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECHHHCCCCHHHHHEEEEE
NARPIKIGLAVLVDRGHRELPIRADFVGKNIPTSKEETVSVYLEEMDQRNAVIIK
CCCCCEEEEEEEEECCCCCCCEEHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA