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The map label for this gene is mraY

Identifier: 82750789

GI number: 82750789

Start: 1127579

End: 1128544

Strand: Direct

Name: mraY

Synonym: SAB1046

Alternate gene names: 82750789

Gene position: 1127579-1128544 (Clockwise)

Preceding gene: 82750788

Following gene: 82750790

Centisome position: 41.11

GC content: 32.61

Gene sequence:

>966_bases
ATGATTTTTGTATATGCGTTATTAGCGCTAGTGATTACATTTGTTTTGGTACCTGTTTTAATACCTACATTAAAAAGGAT
GAAATTTGGTCAAAGTATTCGAGAAGAAGGCCCACAAAGCCATATGAAGAAGACTGGTACACCAACGATGGGTGGACTAA
CATTTCTATTAAGTATTGTGATAACGTCTTTGGTGGCTATTATATTTGTAGAACAAGCTAATCCGATCATACTGTTATTA
TTTGTGACGATTGGTTTTGGGTTAATTGGTTTTATAGATGATTATATTATTGTTGTTAAAAAGAATAACCAAGGTTTAAC
AAGTAAACAGAAGTTTTTGGCGCAAATTGGTATTGCGATTATTTTCTTTGTTTTAAGTAATGTGTTTCATTTGGTGAATT
TTTCTACGAGCATACATATTCCATTTACGAATGTAGCAATCCCACTATCATTTGCATATGTTATTTTCATTGTTTTTTTG
CAAGTAGGTTTTTCTAATGCGGTAAATTTAACAGATGGTTTAGATGGATTAGCAACTGGACTGTCAATTATCGGATTTAC
AATGTATGCCATCATGAGCTTTGTGTTAGGAGAAACGGCAATTGGTATTTTCTGTATCATTATGTTGTTTGCACTTTTAG
GATTTTTACCATATAACATTAACCCTGCTAAAGTGTTTATGGGAGATACAGGTAGCTTAGCTTTAGGTGGTATATTTGCT
ACGATTTCAATCATGCTTAATCAGGAGTTATCATTAATTTTTATAGGTTTAGTGTTCGTAATTGAAACATTATCTGTTAT
GTTACAAGTCGCTAGCTTTAAATTGACTGGAAAGCGTATATTTAAAATGAGTCCGATACATCATCATTTTGAATTGATAG
GATGGAGCGAATGGAAAGTAGTTACAGTATTTTGGGCTGTTGGTCTGATTTCAGGTTTAATCGGTTTATGGATTGGAGTG
CATTAA

Upstream 100 bases:

>100_bases
AGAAAAATTATAAATTTTGATTACAACTTTGTTTATTTAATTGAAAAATTGATAATATATTAGTGGTTAAAAAAGTCTGG
ATTAAGAAGAGGAGATAGTT

Downstream 100 bases:

>100_bases
GATGCTTAATTACACAGGGTTAGAAAATAAAAATGTATTAGTTGTCGGTTTGGCAAAAAGTGGTTATGAAGCAGCTAAAT
TATTAAGTAAATTAGGTGCG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVEQANPIILLL
FVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFL
QVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGV
H

Sequences:

>Translated_321_residues
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVEQANPIILLL
FVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFL
QVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGV
H
>Mature_321_residues
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVEQANPIILLL
FVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFL
QVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGV
H

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=331, Percent_Identity=41.9939577039275, Blast_Score=228, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 35174; Mature: 35174

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHH
ITSLVAIIFVEQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHH
IFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFLQVGFSNAVNLTDGLDGLATG
HHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCHHHHHHHH
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCHHHHHHCCCCCHHH
VTVFWAVGLISGLIGLWIGVH
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHH
ITSLVAIIFVEQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHH
IFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFLQVGFSNAVNLTDGLDGLATG
HHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCHHHHHHHH
TISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKV
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCCHHHHHHCCCCCHHH
VTVFWAVGLISGLIGLWIGVH
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA