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The map label for this gene is menB

Identifier: 82750657

GI number: 82750657

Start: 988381

End: 989202

Strand: Direct

Name: menB

Synonym: SAB0912

Alternate gene names: 82750657

Gene position: 988381-989202 (Clockwise)

Preceding gene: 82750656

Following gene: 82750667

Centisome position: 36.04

GC content: 38.32

Gene sequence:

>822_bases
ATGACTAACAGACAATGGGAAACACTTAGAGAATATGATGAAATCAATTATGAATTTTACGAAGGGATTGCTAAGGTAAC
AATAAATCGCCCTGAAGTACGCAATGCGTTTACACCTAAAACAGTTGCTGAAATGATTGACGCATTTTCACGTGCACGTG
ATGATCAAAACGTTTCAGTTATCGTATTAACTGGTGAAGGTGATTTAGCATTCTGTTCTGGTGGTGACCAGAAGAAACGT
GGACATGGTGGTTATGTAGGTGAAGACCAAATCCCTCGCTTAAATGTATTAGATTTACAGCGTTTAATTCGTATTATTCC
AAAACCGGTTATTGCGATGGTAAAAGGTTATGCTGTAGGTGGCGGTAATGTACTAAATGTTGTTTGTGACTTAACGATTG
CTGCTGATAATGCTATTTTTGGACAAACTGGTCCTAAAGTAGGTTCATTTGATGCAGGTTATGGTTCAGGATATTTAGCA
CGTATCGTTGGACATAAGAAAGCACGTGAAATCTGGTACTTATGTCGTCAATACAATGCACAAGAAGCTTTAGATATGGG
TCTAGTAAATACAGTGGTACCTTTAGATAAAGTTGAAGATGAAACTGTGCAATGGTGTAAAGAGATTATGAAACACTCAC
CAACTGCTTTACGATTCCTTAAAGCAGCTATGAATGCTGACACAGATGGTTTAGCTGGTTTACAACAAATGGCTGGGGAT
GCAACATTGCTTTATTACACAACTGATGAAGCGAAAGAAGGCCGTGATGCGTTTAAAGAAAAACGTGATCCTGACTTCGA
TCAATTCCCTAAATTCCCATAA

Upstream 100 bases:

>100_bases
AGTAAATGTAAATTAATTTCTGCTACAGGTCATACAATTCATGTGGAAGATAGTGATGAATTTGATACAATGATATTAGG
ACTTTTAAAGGAGGAGCAAA

Downstream 100 bases:

>100_bases
GTTATTTTGAATATGATATTAAGTCGCTTGCGTCGTTTATTTGCGATGACGAGTGGCTTTTTTATTTTATAAGAATTTAA
AAGGGGCTTTTAATTAATTA

Product: naphthoate synthase

Products: NA

Alternate protein names: DHNA-CoA synthase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTNRQWETLREYDEINYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKR
GHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLA
RIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGD
ATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP

Sequences:

>Translated_273_residues
MTNRQWETLREYDEINYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKR
GHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLA
RIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGD
ATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP
>Mature_272_residues
TNRQWETLREYDEINYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRG
HGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLAR
IVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDA
TLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP

Specific function: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) (Probable) [H]

COG id: COG0447

COG function: function code H; Dihydroxynaphthoic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=243, Percent_Identity=32.0987654320988, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI31542718, Length=266, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI45643119, Length=204, Percent_Identity=30.8823529411765, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI260275230, Length=204, Percent_Identity=30.8823529411765, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI260274832, Length=204, Percent_Identity=30.8823529411765, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI4502327, Length=278, Percent_Identity=28.7769784172662, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI70995211, Length=236, Percent_Identity=27.5423728813559, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1788597, Length=272, Percent_Identity=64.7058823529412, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1787659, Length=245, Percent_Identity=33.469387755102, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI221142681, Length=257, Percent_Identity=31.1284046692607, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI87082183, Length=263, Percent_Identity=27.7566539923954, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787660, Length=252, Percent_Identity=29.3650793650794, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=33.0645161290323, Blast_Score=117, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17554946, Length=249, Percent_Identity=30.9236947791165, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=222, Percent_Identity=30.1801801801802, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17560910, Length=189, Percent_Identity=32.8042328042328, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17549921, Length=207, Percent_Identity=28.9855072463768, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=274, Percent_Identity=24.8175182481752, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=223, Percent_Identity=26.9058295964126, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=263, Percent_Identity=26.615969581749, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129971, Length=269, Percent_Identity=34.2007434944238, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24653477, Length=269, Percent_Identity=34.2007434944238, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24653139, Length=255, Percent_Identity=29.4117647058824, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21357171, Length=181, Percent_Identity=31.4917127071823, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19922422, Length=261, Percent_Identity=24.5210727969349, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24650670, Length=267, Percent_Identity=27.7153558052434, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24654903, Length=266, Percent_Identity=24.4360902255639, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR010198 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.3.36 [H]

Molecular weight: Translated: 30398; Mature: 30267

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRQWETLREYDEINYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSV
CCCCHHHHHHHHHHCCHHHHHCHHHEEECCCHHCCCCCHHHHHHHHHHHHHCCCCCCEEE
IVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVG
EEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCC
GGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNA
CCHHEEHEEEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCH
QEALDMGLVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGD
HHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCC
ATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP
EEEEEEECCCHHHHHHHHHHCCCCCHHHCCCCC
>Mature Secondary Structure 
TNRQWETLREYDEINYEFYEGIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSV
CCCHHHHHHHHHHCCHHHHHCHHHEEECCCHHCCCCCHHHHHHHHHHHHHCCCCCCEEE
IVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVG
EEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCC
GGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNA
CCHHEEHEEEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCH
QEALDMGLVNTVVPLDKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGD
HHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCC
ATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP
EEEEEEECCCHHHHHHHHHHCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA