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The map label for this gene is rocD

Identifier: 82750572

GI number: 82750572

Start: 889323

End: 890513

Strand: Direct

Name: rocD

Synonym: SAB0824

Alternate gene names: 82750572

Gene position: 889323-890513 (Clockwise)

Preceding gene: 82750571

Following gene: 82750573

Centisome position: 32.43

GC content: 35.68

Gene sequence:

>1191_bases
ATGACTAAATCTGAAAAAATTATTGAGTTAACAAATCATTACGGAGCACATAATTATTTACCATTGCCAATTGTCATTTC
AGAAGCTGAAGGGGTATGGGTTAAAGATCCTGAAGGCAATAAATATATGGATATGTTATCTGCATATTCCGCTGTTAACC
AAGGTCATAGACATCCGAAAATTATTCAAGCATTAAAAGATCAAGCTGATAAAGTGACTCTAGTTTCACGTGCTTTTCAT
AGTGACAACTTAGGAGAATGGTACGAAAAAATTTGTAAACTGACAGGTAAAGATAAAGCTTTACCAATGAATACAGGTGC
TGAAGCAGTAGAAACAGCTTTGAAAGCAGCACGACGCTGGGCATACGATGTTAAAGGAATTGAGCCAAATAAAGCAGAAA
TCATTGCATTTAATGGTAACTTCCATGGTCGAACAATGGCGCCAGTTTCATTATCATCAGAAGCAGAATACCAACGTGGT
TATGGTCCGTTATTAGATGGATTTAGAAAAGTTGATTTTAGAGATGTAGATGCATTGAAAGCTGCAATTAATGAAAATAC
TGCAGCAGTTTTAGTAGAACCAATTCAAGGTGAAGCGGGTATAAATATACCGCCAGAAGGATATTTGAAAGCAATTAGAG
AATTATGTGATGAACATAATGTCTTATTTATTGCTGACGAAATCCAAGCAGGATTAGGTCGTTCGGGTAAATTATTTGCT
ACGGATTGGGATAATGTAAAACCTGATGTCTATATTTTAGGTAAAGCACTAGGTGGTGGTGTCTTCCCAATTTCTGTTGT
ATTAGCAGATAAAGAAGTATTAGATGTCTTTACACCTGGCTCACATGGTTCAACATTTGGTGGTAATCCACTTGCTTGTG
CTGCATCGATTGCTGCATTAGATGTTATCGTTGATGAGGATTTACCAGGGCGCTCTTTAGAATTAGGAGATTATTTTAAA
GAACAATTAAAGCAAATTGATCATCCATCAATTAAAGAAGTCCGTGGACGTGGTTTGTTTATAGGTGTGGAACTTAATGA
AAGTGCTAGACCATATTGTGAAGCTTTGAAAGAAGAAGGCTTATTATGTAAAGAAACGCATGATACTGTCATTCGTTTTG
CACCACCATTAATTATTACTAAAGAAGAATTGGACCTTGCACTTGAAAAAATAAGACATGTATTTCAATAA

Upstream 100 bases:

>100_bases
CATCTTTTTTGGTGGAAAAGTATCTGCTTTGAAAACTAATGTAATTATTTGGATAATGTTTCATGTATAATAGTTATAAA
TGATGAAAAGGGGAGATATG

Downstream 100 bases:

>100_bases
TGTCAAAAAGTTGTAACAATCAGTTTGTAAGGGCTTTAAAAAGGAATACGTTATGTTACAATATGTTTCAAAGCGAAATC
ATTAGGTAAAGAAGAGGCGA

Product: ornithine--oxo-acid transaminase

Products: NA

Alternate protein names: OAT 2; Ornithine--oxo-acid aminotransferase 2 [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFH
SDNLGEWYEKICKLTGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRG
YGPLLDGFRKVDFRDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFK
EQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ

Sequences:

>Translated_396_residues
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFH
SDNLGEWYEKICKLTGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRG
YGPLLDGFRKVDFRDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFK
EQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>Mature_395_residues
TKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHS
DNLGEWYEKICKLTGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGY
GPLLDGFRKVDFRDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFAT
DWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKE
QLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=393, Percent_Identity=49.3638676844784, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=47.2789115646259, Blast_Score=282, Evalue=3e-76,
Organism=Homo sapiens, GI13994255, Length=431, Percent_Identity=29.6983758700696, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=28.0952380952381, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI226442709, Length=388, Percent_Identity=28.0927835051546, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=27.3809523809524, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI24119277, Length=411, Percent_Identity=27.2506082725061, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI188536080, Length=418, Percent_Identity=24.1626794258373, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38679950, Length=418, Percent_Identity=24.1626794258373, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI38679946, Length=418, Percent_Identity=24.1626794258373, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1789759, Length=383, Percent_Identity=37.3368146214099, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI145693181, Length=374, Percent_Identity=37.1657754010695, Blast_Score=257, Evalue=9e-70,
Organism=Escherichia coli, GI1788044, Length=379, Percent_Identity=36.4116094986807, Blast_Score=247, Evalue=8e-67,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=33.9108910891089, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1789016, Length=412, Percent_Identity=33.0097087378641, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786991, Length=397, Percent_Identity=30.4785894206549, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786349, Length=298, Percent_Identity=27.8523489932886, Blast_Score=105, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=49.616368286445, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI25144274, Length=270, Percent_Identity=46.6666666666667, Blast_Score=251, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI71981843, Length=173, Percent_Identity=47.9768786127168, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=31.4814814814815, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=421, Percent_Identity=29.4536817102138, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=415, Percent_Identity=26.2650602409639, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323470, Length=410, Percent_Identity=48.780487804878, Blast_Score=373, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6324432, Length=372, Percent_Identity=33.0645161290323, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6324386, Length=406, Percent_Identity=26.1083743842365, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=371, Percent_Identity=27.2237196765499, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21357415, Length=394, Percent_Identity=49.238578680203, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI161085790, Length=431, Percent_Identity=29.9303944315545, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI28574759, Length=424, Percent_Identity=29.7169811320755, Blast_Score=164, Evalue=7e-41,
Organism=Drosophila melanogaster, GI21356575, Length=447, Percent_Identity=27.2930648769575, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI281366494, Length=421, Percent_Identity=24.7030878859857, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667139, Length=421, Percent_Identity=24.7030878859857, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24667143, Length=421, Percent_Identity=24.7030878859857, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 43547; Mature: 43416

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPK
CCCCCHHHHHHCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLTGKDKALPMNTGAEAVETALKAARRW
HHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFRDVDALK
HHCCCCCCCCCEEEEEECCCCCCCEECCEECCCCCHHHCCCCHHHHHHHCCCCHHHHHHH
AAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAAL
ECCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHEEECCCCCCCCCCCCHHHHHHHHHHE
DVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEG
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
CEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPK
CCCCHHHHHHCCCCCCCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHH
IIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLTGKDKALPMNTGAEAVETALKAARRW
HHHHHHHCCCCEEHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
AYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFRDVDALK
HHCCCCCCCCCEEEEEECCCCCCCEECCEECCCCCHHHCCCCHHHHHHHCCCCHHHHHHH
AAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFA
HHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCEEE
TDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAAL
ECCCCCCCCEEEEEEHHCCCCCEEEEEEECCHHHEEECCCCCCCCCCCCHHHHHHHHHHE
DVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEG
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHCC
LLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
CEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA