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The map label for this gene is hlgB [H]

Identifier: 82750533

GI number: 82750533

Start: 851630

End: 852598

Strand: Direct

Name: hlgB [H]

Synonym: SAB0783

Alternate gene names: 82750533

Gene position: 851630-852598 (Clockwise)

Preceding gene: 82750532

Following gene: 82750536

Centisome position: 31.05

GC content: 32.4

Gene sequence:

>969_bases
ATGAAAATTAAGAATATAGTCAAATCATCAGTCGCTACATCAATTACATTTATCATGCTATCAAATACAGTTGATGCAGC
TCAACATATCACACCTGTCAGCGAGAAAAAAGTGGATGACAAAATCACTTTGTACAAAACGACTGCTACATCAGATTCTG
ACAAATTAAAAATTTCTCAAATTCTAACTTTTAATTTTATTAAAGACAAAAGTTATGATAAAGACACATTAATACTAAAA
GCTGCCGGAAACATTTACTCAGGCTATACCCAACCCACTTCTGATAGTAGTATAAATTCACAATTTTATTGGGGAGCTAA
GTATAATGTTTTTGTTAGCTCGGAGTCCAAAGATTCTGTAAATATTGTTGACTACGCGCCTAAAAATCAAAATGAAGAAT
TTCAAGTTCAACAAACATTAGGTTATTCATATGGCGGAGATATTAATATAATAAATGGATTAACTGGTGGATTGAACGGG
TCAAAATCATTTTCAGAAACGATTAATTATAAGCAAGAAAGCTACAGAACTACGATTGATAGGAAAATAAATCACAAATT
AATCGGCTGGGGTGTCGAGGCACATAAAATCATGAATAATGGTTGGGGACCATATGGCAGAGATAGTAGTGATTCATTAT
ATGGAAACGAACTATTTTTAGGTGGCAGACAGAGTAGCTCGAATGCTAATCAAAATTTCTTACCAACACATCAAATGCCC
ATATTAGCACGTGGTAATTTCAATCCAGAATTTATAAGCGTACTTTCTCACAAACAAAAGGATGTTAAAAAATCTAAAAT
TAAAGTGACTTATCAAAGACAAATGGATCGGTATGAAAATTTTTGGAACAACTTGCACTGGATAGGTTATAATATTAAGA
ATCAAAAGAGAGCAACACACACATCAATTTATGAAATTGATTGGGAAAAACACACGGTTAAATTAGTAGCTTCGCAATCT
AGCGAATAA

Upstream 100 bases:

>100_bases
CCAGAAAGAAAACATAATGAATTTGTAAACAGAAACTTTGTGGTCAAATATGAAGTGAATTGGAAAACGCACGAAATTAA
AGTAAAGGGGCACAACTAAT

Downstream 100 bases:

>100_bases
ACTACTTCCTAGATACCGTGGATTTTATAATAGGCTATGATTCGAAAAGAAATCTAATTACTCAGATATTAGGTGACTTA
TGGGTAGAAATCAGTTAATA

Product: Panton-Valentine leukocidin LukF-PV chain precursor

Products: NA

Alternate protein names: H-gamma-1; H-gamma-I [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKIKNIVKSSVATSITFIMLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDSDKLKISQILTFNFIKDKSYDKDTLILK
AAGNIYSGYTQPTSDSSINSQFYWGAKYNVFVSSESKDSVNIVDYAPKNQNEEFQVQQTLGYSYGGDINIINGLTGGLNG
SKSFSETINYKQESYRTTIDRKINHKLIGWGVEAHKIMNNGWGPYGRDSSDSLYGNELFLGGRQSSSNANQNFLPTHQMP
ILARGNFNPEFISVLSHKQKDVKKSKIKVTYQRQMDRYENFWNNLHWIGYNIKNQKRATHTSIYEIDWEKHTVKLVASQS
SE

Sequences:

>Translated_322_residues
MKIKNIVKSSVATSITFIMLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDSDKLKISQILTFNFIKDKSYDKDTLILK
AAGNIYSGYTQPTSDSSINSQFYWGAKYNVFVSSESKDSVNIVDYAPKNQNEEFQVQQTLGYSYGGDINIINGLTGGLNG
SKSFSETINYKQESYRTTIDRKINHKLIGWGVEAHKIMNNGWGPYGRDSSDSLYGNELFLGGRQSSSNANQNFLPTHQMP
ILARGNFNPEFISVLSHKQKDVKKSKIKVTYQRQMDRYENFWNNLHWIGYNIKNQKRATHTSIYEIDWEKHTVKLVASQS
SE
>Mature_322_residues
MKIKNIVKSSVATSITFIMLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDSDKLKISQILTFNFIKDKSYDKDTLILK
AAGNIYSGYTQPTSDSSINSQFYWGAKYNVFVSSESKDSVNIVDYAPKNQNEEFQVQQTLGYSYGGDINIINGLTGGLNG
SKSFSETINYKQESYRTTIDRKINHKLIGWGVEAHKIMNNGWGPYGRDSSDSLYGNELFLGGRQSSSNANQNFLPTHQMP
ILARGNFNPEFISVLSHKQKDVKKSKIKVTYQRQMDRYENFWNNLHWIGYNIKNQKRATHTSIYEIDWEKHTVKLVASQS
SE

Specific function: Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aerolysin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003963
- InterPro:   IPR001340
- InterPro:   IPR016183 [H]

Pfam domain/function: PF07968 Leukocidin [H]

EC number: NA

Molecular weight: Translated: 36556; Mature: 36556

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKNIVKSSVATSITFIMLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDSDKLKISQ
CCHHHHHHHHHHHEEEEEEEECCHHHHHHCCCCHHHCCCCEEEEEEEECCCCCCCEEEEE
ILTFNFIKDKSYDKDTLILKAAGNIYSGYTQPTSDSSINSQFYWGAKYNVFVSSESKDSV
EEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCCE
NIVDYAPKNQNEEFQVQQTLGYSYGGDINIINGLTGGLNGSKSFSETINYKQESYRTTID
EEEEECCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHCCCHHHHHHHHH
RKINHKLIGWGVEAHKIMNNGWGPYGRDSSDSLYGNELFLGGRQSSSNANQNFLPTHQMP
HHCCCEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
ILARGNFNPEFISVLSHKQKDVKKSKIKVTYQRQMDRYENFWNNLHWIGYNIKNQKRATH
EEEECCCCHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
TSIYEIDWEKHTVKLVASQSSE
CEEEEEECCCEEEEEEECCCCC
>Mature Secondary Structure
MKIKNIVKSSVATSITFIMLSNTVDAAQHITPVSEKKVDDKITLYKTTATSDSDKLKISQ
CCHHHHHHHHHHHEEEEEEEECCHHHHHHCCCCHHHCCCCEEEEEEEECCCCCCCEEEEE
ILTFNFIKDKSYDKDTLILKAAGNIYSGYTQPTSDSSINSQFYWGAKYNVFVSSESKDSV
EEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEECCEEEEEEECCCCCCE
NIVDYAPKNQNEEFQVQQTLGYSYGGDINIINGLTGGLNGSKSFSETINYKQESYRTTID
EEEEECCCCCCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHCCCHHHHHHHHH
RKINHKLIGWGVEAHKIMNNGWGPYGRDSSDSLYGNELFLGGRQSSSNANQNFLPTHQMP
HHCCCEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
ILARGNFNPEFISVLSHKQKDVKKSKIKVTYQRQMDRYENFWNNLHWIGYNIKNQKRATH
EEEECCCCHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
TSIYEIDWEKHTVKLVASQSSE
CEEEEEECCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA