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The map label for this gene is comFA

Identifier: 82750454

GI number: 82750454

Start: 768601

End: 769680

Strand: Direct

Name: comFA

Synonym: SAB0702

Alternate gene names: 82750454

Gene position: 768601-769680 (Clockwise)

Preceding gene: 82750453

Following gene: 82750455

Centisome position: 28.03

GC content: 32.04

Gene sequence:

>1080_bases
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAATGAGACAAACGATTTTGTTATATGCAGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGACGACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAAATATAGACATACTACACCA
GCAATCAAGTCAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACGGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAGTTTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACGATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGATCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGCTATTTTAAACTTAATAATAATATTCAGAAAA
TGTTATATCGAATTTTACAAGATCAAATTAATAAACAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATGATT
AAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATATGTCCATAGCGAGGATGTTTTTCGCTTTGAAAAAGT
TGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATTTGG
ATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTAGAA
TGTCCTACTGGAAAAGTATTGTTTTTTCATGAAGGAGTAAGTATGAATATGATTCAAGCAAAAAAAGAGATTCAAAAGAT
GAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Upstream 100 bases:

>100_bases
TCAATGTGAAAGTACAAATCCAAAGCATTTTTATCAGTATGATTCCTCAGTACATTCCAAGAAAATTGTATATTGCAGAA
ATTGTATATCACTGGGTCGA

Downstream 100 bases:

>100_bases
TTGTTTGAGTTGTGGTGCTAAGTTATATGAAAATATAACCATTTATAATTTGTTCAAGAAACCTAATAGATTATGTGACA
GATGCAAAGAGAATTGGGAC

Product: late competence operon protein FA

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRMRQTILLYAVTGAGKTEMMFQGIQYARRQGDNIAIVS
PRVDVVVEISKRIKDAFLNENIDILHQQSSQQFEGHFVVCTVHQLYRFKRHFDTIFIDEVDAFPLSMDKSLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPDRFHKKSLPVPKYRYFKLNNNIQKMLYRILQDQINKQRYTLVFFNNIETMI
KTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLE
CPTGKVLFFHEGVSMNMIQAKKEIQKMNKLALKRGWIDE

Sequences:

>Translated_359_residues
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRMRQTILLYAVTGAGKTEMMFQGIQYARRQGDNIAIVS
PRVDVVVEISKRIKDAFLNENIDILHQQSSQQFEGHFVVCTVHQLYRFKRHFDTIFIDEVDAFPLSMDKSLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPDRFHKKSLPVPKYRYFKLNNNIQKMLYRILQDQINKQRYTLVFFNNIETMI
KTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLE
CPTGKVLFFHEGVSMNMIQAKKEIQKMNKLALKRGWIDE
>Mature_359_residues
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRMRQTILLYAVTGAGKTEMMFQGIQYARRQGDNIAIVS
PRVDVVVEISKRIKDAFLNENIDILHQQSSQQFEGHFVVCTVHQLYRFKRHFDTIFIDEVDAFPLSMDKSLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPDRFHKKSLPVPKYRYFKLNNNIQKMLYRILQDQINKQRYTLVFFNNIETMI
KTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLE
CPTGKVLFFHEGVSMNMIQAKKEIQKMNKLALKRGWIDE

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 41977; Mature: 41977

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRMRQTILLYAVTGAGKTE
CCCCEEEEEECCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHH
MMFQGIQYARRQGDNIAIVSPRVDVVVEISKRIKDAFLNENIDILHQQSSQQFEGHFVVC
HHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCEEEE
TVHQLYRFKRHFDTIFIDEVDAFPLSMDKSLQQALKSSSKVEHATIYMTATPPKQLLSEI
EHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHC
PHENIIKLPDRFHKKSLPVPKYRYFKLNNNIQKMLYRILQDQINKQRYTLVFFNNIETMI
CCCCEECCCHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHH
KTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDA
HHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEEEEEEHHHHCCCEEECCEEEEEEC
HQYTQEALIQIAGRVGRKLECPTGKVLFFHEGVSMNMIQAKKEIQKMNKLALKRGWIDE
HHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRMRQTILLYAVTGAGKTE
CCCCEEEEEECCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHH
MMFQGIQYARRQGDNIAIVSPRVDVVVEISKRIKDAFLNENIDILHQQSSQQFEGHFVVC
HHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCEEEE
TVHQLYRFKRHFDTIFIDEVDAFPLSMDKSLQQALKSSSKVEHATIYMTATPPKQLLSEI
EHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHC
PHENIIKLPDRFHKKSLPVPKYRYFKLNNNIQKMLYRILQDQINKQRYTLVFFNNIETMI
CCCCEECCCHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHH
KTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDA
HHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEEEEEEHHHHCCCEEECCEEEEEEC
HQYTQEALIQIAGRVGRKLECPTGKVLFFHEGVSMNMIQAKKEIQKMNKLALKRGWIDE
HHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]