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The map label for this gene is macB [H]

Identifier: 82749909

GI number: 82749909

Start: 172967

End: 173953

Strand: Direct

Name: macB [H]

Synonym: SAB0139

Alternate gene names: 82749909

Gene position: 172967-173953 (Clockwise)

Preceding gene: 82749908

Following gene: 82749910

Centisome position: 6.31

GC content: 30.7

Gene sequence:

>987_bases
TTGATTAGCTTTACTTTTAAAGTTGATGAGAAAATCAAAAAGTATCCTTTTAATCAAAGAGATATAGAGTTGGTAAATCA
AGTTGATGGCGTACTAGATGCGAAGCTAAAGGAAAATAAAGAAGAAGGAATTGAAGCCACAATAACTAATGTCCAGAAAA
AAAGTGACATCTTCATTATAAAAAAACAAAATTTACACTCTTTTAAAGTAGGTAGAGGGTTTGATAAAGAGGATAATGAA
TTACGTAAGAAAATAGTGGTTATAAATGATCAAGTAGCAAAAACTATATTCAATAATAATGCTATTGGTAAATCGCTATA
TATTGAGGGACAGGGATTTGAAGTCATAGGAATTACGGATAAACTATATTCTGACTCATCTACCGTTATAATGCCTGAAA
ATACATTCAACTACTATATGGGACACTTACATCAAGGTCTGCCTACCTTACAGATAATTATTGAAGATGGTTACAATAAA
AAAACTGTAGTTAAAAAAGTAGAATCACTATTAAATAAAAAAGGATCGGGCTCTGTTTTAGGTGAGTATACATATACAGA
CACTGAAGAAATTATCAAAAGTATTGATAAAATTTTTGATAGTATTACTTATTTTGTAGCAGCTGTTGCCGGTATTTCAC
TTTTTATTGCTGGTATTGGAGTTATGAATGTCATGTATATATCTGTAGCTGAAAGAACAGAAGAAATTGCGATACGACGT
GCATTTGGTGTAAAAAGTCGAGATATTGAACTACTATTTTTAATAGAGAGCATTTTAATATGTGTGACAAGTGGTTTTAT
TGGACTTATTTTAGGTGTTGTGTTTGCAACAATAATTGATGTATTAACACCAGATTATATTAAAAGTGTAGTAAGTTTGA
GTTCTGTCATTATTGCGGTTAGTGTGTCGATATTAATTGGACTTCTTTTTGGATGGATACCAGCTCGCGCAGCATCTAAG
AAAGAGCTCATAGATATTATAAAATAG

Upstream 100 bases:

>100_bases
CGGTATTTCTTCTGTTATTACGATAATGTCTTTAGGAAATGGCTTTAAAAAAACTGCTGCTGATCAATTTTCAGATGCTG
GCGCCGGAAAATAAGAAGCG

Downstream 100 bases:

>100_bases
TAAATTTAAAATGGTAAAAGTACTGAAGACTAATTATCATATTAAACTGACTATCAACACCAACGATGGAAATGCGTATT
AGAATAAAAGTAAGATATTT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MISFTFKVDEKIKKYPFNQRDIELVNQVDGVLDAKLKENKEEGIEATITNVQKKSDIFIIKKQNLHSFKVGRGFDKEDNE
LRKKIVVINDQVAKTIFNNNAIGKSLYIEGQGFEVIGITDKLYSDSSTVIMPENTFNYYMGHLHQGLPTLQIIIEDGYNK
KTVVKKVESLLNKKGSGSVLGEYTYTDTEEIIKSIDKIFDSITYFVAAVAGISLFIAGIGVMNVMYISVAERTEEIAIRR
AFGVKSRDIELLFLIESILICVTSGFIGLILGVVFATIIDVLTPDYIKSVVSLSSVIIAVSVSILIGLLFGWIPARAASK
KELIDIIK

Sequences:

>Translated_328_residues
MISFTFKVDEKIKKYPFNQRDIELVNQVDGVLDAKLKENKEEGIEATITNVQKKSDIFIIKKQNLHSFKVGRGFDKEDNE
LRKKIVVINDQVAKTIFNNNAIGKSLYIEGQGFEVIGITDKLYSDSSTVIMPENTFNYYMGHLHQGLPTLQIIIEDGYNK
KTVVKKVESLLNKKGSGSVLGEYTYTDTEEIIKSIDKIFDSITYFVAAVAGISLFIAGIGVMNVMYISVAERTEEIAIRR
AFGVKSRDIELLFLIESILICVTSGFIGLILGVVFATIIDVLTPDYIKSVVSLSSVIIAVSVSILIGLLFGWIPARAASK
KELIDIIK
>Mature_328_residues
MISFTFKVDEKIKKYPFNQRDIELVNQVDGVLDAKLKENKEEGIEATITNVQKKSDIFIIKKQNLHSFKVGRGFDKEDNE
LRKKIVVINDQVAKTIFNNNAIGKSLYIEGQGFEVIGITDKLYSDSSTVIMPENTFNYYMGHLHQGLPTLQIIIEDGYNK
KTVVKKVESLLNKKGSGSVLGEYTYTDTEEIIKSIDKIFDSITYFVAAVAGISLFIAGIGVMNVMYISVAERTEEIAIRR
AFGVKSRDIELLFLIESILICVTSGFIGLILGVVFATIIDVLTPDYIKSVVSLSSVIIAVSVSILIGLLFGWIPARAASK
KELIDIIK

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=269, Percent_Identity=28.2527881040892, Blast_Score=124, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 36522; Mature: 36522

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFTFKVDEKIKKYPFNQRDIELVNQVDGVLDAKLKENKEEGIEATITNVQKKSDIFII
CEEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHCCCCEEEE
KKQNLHSFKVGRGFDKEDNELRKKIVVINDQVAKTIFNNNAIGKSLYIEGQGFEVIGITD
EECCCCEEECCCCCCCCHHHHHHEEEEECHHHHHHHHCCCCCCCEEEEECCCEEEEEECH
KLYSDSSTVIMPENTFNYYMGHLHQGLPTLQIIIEDGYNKKTVVKKVESLLNKKGSGSVL
HHCCCCCCEEECCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCEE
GEYTYTDTEEIIKSIDKIFDSITYFVAAVAGISLFIAGIGVMNVMYISVAERTEEIAIRR
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGVKSRDIELLFLIESILICVTSGFIGLILGVVFATIIDVLTPDYIKSVVSLSSVIIAV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
SVSILIGLLFGWIPARAASKKELIDIIK
HHHHHHHHHHHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure
MISFTFKVDEKIKKYPFNQRDIELVNQVDGVLDAKLKENKEEGIEATITNVQKKSDIFII
CEEEEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHCCCCEEEE
KKQNLHSFKVGRGFDKEDNELRKKIVVINDQVAKTIFNNNAIGKSLYIEGQGFEVIGITD
EECCCCEEECCCCCCCCHHHHHHEEEEECHHHHHHHHCCCCCCCEEEEECCCEEEEEECH
KLYSDSSTVIMPENTFNYYMGHLHQGLPTLQIIIEDGYNKKTVVKKVESLLNKKGSGSVL
HHCCCCCCEEECCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCEE
GEYTYTDTEEIIKSIDKIFDSITYFVAAVAGISLFIAGIGVMNVMYISVAERTEEIAIRR
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGVKSRDIELLFLIESILICVTSGFIGLILGVVFATIIDVLTPDYIKSVVSLSSVIIAV
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
SVSILIGLLFGWIPARAASKKELIDIIK
HHHHHHHHHHHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA