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The map label for this gene is nutA [H]

Identifier: 82749800

GI number: 82749800

Start: 31231

End: 33549

Strand: Direct

Name: nutA [H]

Synonym: SAB0023

Alternate gene names: 82749800

Gene position: 31231-33549 (Clockwise)

Preceding gene: 82749799

Following gene: 82749801

Centisome position: 1.14

GC content: 38.59

Gene sequence:

>2319_bases
ATGAAAGCTTTATTACTTAAAACAAGTGTATGGCTCGTTTTGCTTTTTAGTGCAATGGGATTATGGCATGTCTCGAACGC
GGCTGAGCAGCATACACCAATGAAAGCACATGTAGTAACAACGATAGACAAAGCAACAACAGATAAGCAACAAGTAACGC
CAACCAAGGAAGCGGCTCATCATTATGGTGAAGAAGCGGCAACCAACGTATCAGCATCAGCGCAGGGAACAGTTGATGAT
ATAAACAACAAAGTAACTTCCAACGCACCATCTAACAAACCATCTACAGCAGTTTCAGCAACAGTAAACGAAACGCGCGA
TGTAGATACACAACAAGCCTCAACACAAAAACCAACTCGCACAGCAACATACAAATTATCAAATGCTAAAACAGCATCAC
TTTCACCACGAATGTTTGCTGCCAATGCACCACAAACAACAACACATAAAATATTACATACAAATGATATCCATGGCCGA
CTAGCCGAAGAAAAAGGGCGTGTCATCGGTATGGCTAAATTAAAAACAGTAAAAGAACAAGAAAAGCCTGATTTAATGTT
AGACGCAGGAGACGCATTCCAAGGTTTACCACTTTCAAATCAATCTAAAGGTGAAGAAATGGCTAAAGCAATGAATGCAC
TAGGTTATGATGCTATGGCAGTCGGTAACCATGAATTTGACTTTGGATACGATCAGTTGAAAAAGTTAGAGGGTATGTTA
GACTTCCCGATGCTAAGCACTAACGTTTATAAAGATGGGAAATGCGCGTTTAAACCATCAACGATTGTAACGAAAAATGG
TATTCGTTATGGAATTATTGGCGTAACGACACCAGAAACAAAGACGAAAACAAGACCTGAAGGCATTAAAGGCGTTGAAT
TTAGAGATCCATTACAAAGTGTGACAGCAGAAATGATGCGTATTTATAAAGGCGTAGATACATTTGTTGTTATATCTCAT
TTAGGGATTGATCCATCAACACAAGAAACATGGCGTGGTGATTACTTAGTGAAACAATTAAGTCAAAATCCACAATTGAA
GAAACGTATTACAGTCATTGATGGTCATTCACATACCGTACTTCAAAATGGTCAAATTTATAACAATGATGCATTAGCAC
AAACAGGTACAGCACTTGCGAATATCGGTAAGATTACATTTAATTACCGCAATGGAGAGGTATCGAATATTAAGCCGTCA
TTGATTAACGTTAAAGACGTTGAAAATGTGACACCGAACAAAGCATTAGCTGAACAAATTAATCAAGCTGATCAAACATT
TAGAGCACAAACAGCAGAGGTTATTATTCCAAATAATACCATTGATTTCAAAGGAGAAAGAGATGATGTTAGAACGCGTG
AAACAAATTTAGGAAACGCGATTGCAGATGCTATGGAAGCATATGGCGTTAAGAATTTCTCTAAAAAGCCTGACTTTGCC
GTGACAAATGGTGGAGGTATTCGCGCCTCTATCGCAAAAGGTAAGGTGACACGCTATGATTTAATTTCAGTATTACCATT
TGGAAATACGATTGCGCAAATTGATGTAAAAGGTTCAGACGTCTGGACAGCTTTTGAACATAGTTTAGGCGCACCAACAA
CACAAAAAGATGGTAAGACAGTGTTAACAGCGAATGGTGGTTTACTACATATCTCTGATTCAATCCGTGTTTACTATGAT
ATGGATAAACCATCTGGCAAACGAATTAACGCTATTCAAATTTTAAATAAAGAGACAGGTAAGTTTGAAAATATTGATTT
AAAACGTGTATATCACGTAACGATGAATGACTTCACAGCATCAGGTGGCGACGGATATAGTATGTTCGGTGGCCCTAGAG
AAGAAGGTATTTCATTAGATCAAGTACTAGCAAGTTATTTAAAAACAGCTAACTTAGCTAAGTATGATACGACAGAACCA
CAACGTATGTTATTAGGTAAACCAGCAGTAAGTGAACAACCAGCTAAAGGACAACAAGGTAGCAAAGGTAGTGAGTCTGG
TAAAGATACACAACCAATTGGTAAAGACAAAGTGATGAATCCAGCGAAACAACCAGCGCCAAGTAAAGTTGTGTTGTTAT
CAACGCATAGAGGAACTGTTAGTAGTGGTAGAGAAGGTTCTGGTCGCACATTAGAAGGAACTGCTGTATCAAGTAAGAGT
GGGAAACAATTGGCTAGCATGTCAGCGCCTAAAAGTAGCGCACATAAGAAACAGTTACCAAAAACTGGAGCTGATCAAAG
TTCAAGCCCAGTAGCGATGTTTGTATTAGTAGCAGGTATAGGTTTAATTGCGACTGTACGACGTAGAAAAGCTAGCTAA

Upstream 100 bases:

>100_bases
ATATTAAATGTAATTTATAAATAATTTACATAAAATCAATCATTTTAATATAAGGATTATGATAATATATTGGTGTATGA
CAGTTAATGGAGGGAACGAA

Downstream 100 bases:

>100_bases
AATATATTGAAAACAATACTACTGTATTTCTTAAATAAGAGGTACGGTAGTGTTTTTTTTATGAAAAAAAGCGATAACCG
TTGATAAATATGGGATATAA

Product: 5' nucleotidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MKALLLKTSVWLVLLFSAMGLWHVSNAAEQHTPMKAHVVTTIDKATTDKQQVTPTKEAAHHYGEEAATNVSASAQGTVDD
INNKVTSNAPSNKPSTAVSATVNETRDVDTQQASTQKPTRTATYKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGR
LAEEKGRVIGMAKLKTVKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNALGYDAMAVGNHEFDFGYDQLKKLEGML
DFPMLSTNVYKDGKCAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKGVDTFVVISH
LGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKPDFA
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYD
MDKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEP
QRMLLGKPAVSEQPAKGQQGSKGSESGKDTQPIGKDKVMNPAKQPAPSKVVLLSTHRGTVSSGREGSGRTLEGTAVSSKS
GKQLASMSAPKSSAHKKQLPKTGADQSSSPVAMFVLVAGIGLIATVRRRKAS

Sequences:

>Translated_772_residues
MKALLLKTSVWLVLLFSAMGLWHVSNAAEQHTPMKAHVVTTIDKATTDKQQVTPTKEAAHHYGEEAATNVSASAQGTVDD
INNKVTSNAPSNKPSTAVSATVNETRDVDTQQASTQKPTRTATYKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGR
LAEEKGRVIGMAKLKTVKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNALGYDAMAVGNHEFDFGYDQLKKLEGML
DFPMLSTNVYKDGKCAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKGVDTFVVISH
LGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKPDFA
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYD
MDKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEP
QRMLLGKPAVSEQPAKGQQGSKGSESGKDTQPIGKDKVMNPAKQPAPSKVVLLSTHRGTVSSGREGSGRTLEGTAVSSKS
GKQLASMSAPKSSAHKKQLPKTGADQSSSPVAMFVLVAGIGLIATVRRRKAS
>Mature_772_residues
MKALLLKTSVWLVLLFSAMGLWHVSNAAEQHTPMKAHVVTTIDKATTDKQQVTPTKEAAHHYGEEAATNVSASAQGTVDD
INNKVTSNAPSNKPSTAVSATVNETRDVDTQQASTQKPTRTATYKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGR
LAEEKGRVIGMAKLKTVKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNALGYDAMAVGNHEFDFGYDQLKKLEGML
DFPMLSTNVYKDGKCAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKGVDTFVVISH
LGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKPDFA
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYD
MDKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEP
QRMLLGKPAVSEQPAKGQQGSKGSESGKDTQPIGKDKVMNPAKQPAPSKVVLLSTHRGTVSSGREGSGRTLEGTAVSSKS
GKQLASMSAPKSSAHKKQLPKTGADQSSSPVAMFVLVAGIGLIATVRRRKAS

Specific function: Degradation of extracellular 5'-nucleotides for nutritional needs [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=523, Percent_Identity=29.0630975143403, Blast_Score=155, Evalue=1e-37,
Organism=Escherichia coli, GI1786687, Length=551, Percent_Identity=27.5862068965517, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1790658, Length=264, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573524, Length=554, Percent_Identity=25.0902527075812, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI19922446, Length=498, Percent_Identity=27.1084337349398, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24654424, Length=498, Percent_Identity=27.1084337349398, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24641187, Length=536, Percent_Identity=27.6119402985075, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI19922444, Length=600, Percent_Identity=25.8333333333333, Blast_Score=133, Evalue=6e-31,
Organism=Drosophila melanogaster, GI161076508, Length=478, Percent_Identity=26.1506276150628, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI19921980, Length=478, Percent_Identity=26.1506276150628, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24652512, Length=478, Percent_Identity=26.1506276150628, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221329836, Length=513, Percent_Identity=24.1715399610136, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 83411; Mature: 83411

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50847 GRAM_POS_ANCHORING ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLLKTSVWLVLLFSAMGLWHVSNAAEQHTPMKAHVVTTIDKATTDKQQVTPTKEAAH
CCEEEEHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEEHHCCCCCHHCCCHHHHHH
HYGEEAATNVSASAQGTVDDINNKVTSNAPSNKPSTAVSATVNETRDVDTQQASTQKPTR
HCCHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHCCCCCCC
TATYKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGRLAEEKGRVIGMAKLKTVKEQ
EEEEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHCCCEEEHHHHHHHHHC
EKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNALGYDAMAVGNHEFDFGYDQLKKLEGML
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCC
DFPMLSTNVYKDGKCAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQS
CCCCCCCCCCCCCCEEECCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
VTAEMMRIYKGVDTFVVISHLGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTV
HHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCHHHHHHHHHCCCCCEEEEEEEECCCEEE
LQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPSLINVKDVENVTPNKALAEQI
EECCEEECCCCHHHCCHHHHCCCEEEEEECCCCCCCCCCCEEEHHHCCCCCCCHHHHHHH
NQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKPDFA
HHHHHHHHHCCEEEEECCCEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEE
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKT
EECCCCEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCE
VLTANGGLLHISDSIRVYYDMDKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTA
EEEECCCEEEEECCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEECCEEC
SGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEPQRMLLGKPAVSEQPAKGQQG
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
SKGSESGKDTQPIGKDKVMNPAKQPAPSKVVLLSTHRGTVSSGREGSGRTLEGTAVSSKS
CCCCCCCCCCCCCCCHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEECCEECCCC
GKQLASMSAPKSSAHKKQLPKTGADQSSSPVAMFVLVAGIGLIATVRRRKAS
CCHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKALLLKTSVWLVLLFSAMGLWHVSNAAEQHTPMKAHVVTTIDKATTDKQQVTPTKEAAH
CCEEEEHHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEEEHHCCCCCHHCCCHHHHHH
HYGEEAATNVSASAQGTVDDINNKVTSNAPSNKPSTAVSATVNETRDVDTQQASTQKPTR
HCCHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHCCCCCCC
TATYKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGRLAEEKGRVIGMAKLKTVKEQ
EEEEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHCCCEEEHHHHHHHHHC
EKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNALGYDAMAVGNHEFDFGYDQLKKLEGML
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCC
DFPMLSTNVYKDGKCAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQS
CCCCCCCCCCCCCCEEECCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
VTAEMMRIYKGVDTFVVISHLGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTV
HHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCHHHHHHHHHCCCCCEEEEEEEECCCEEE
LQNGQIYNNDALAQTGTALANIGKITFNYRNGEVSNIKPSLINVKDVENVTPNKALAEQI
EECCEEECCCCHHHCCHHHHCCCEEEEEECCCCCCCCCCCEEEHHHCCCCCCCHHHHHHH
NQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKPDFA
HHHHHHHHHCCEEEEECCCEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEE
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKT
EECCCCEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCE
VLTANGGLLHISDSIRVYYDMDKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTA
EEEECCCEEEEECCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEECCEEC
SGGDGYSMFGGPREEGISLDQVLASYLKTANLAKYDTTEPQRMLLGKPAVSEQPAKGQQG
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
SKGSESGKDTQPIGKDKVMNPAKQPAPSKVVLLSTHRGTVSSGREGSGRTLEGTAVSSKS
CCCCCCCCCCCCCCCHHCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEECCEECCCC
GKQLASMSAPKSSAHKKQLPKTGADQSSSPVAMFVLVAGIGLIATVRRRKAS
CCHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2016269; 12620739 [H]