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The map label for this gene is rnpA [H]

Identifier: 82703891

GI number: 82703891

Start: 3183629

End: 3183889

Strand: Reverse

Name: rnpA [H]

Synonym: Nmul_A2778

Alternate gene names: 82703891

Gene position: 3183889-3183629 (Counterclockwise)

Preceding gene: 82703892

Following gene: 82703890

Centisome position: 99.99

GC content: 55.56

Gene sequence:

>261_bases
TTGCTTCAGGTTTTCGCTAAGCCCAACGGTTTATTACATTCCAGGTTGGGATTGATAGTGGCAGGTAAAATCGAACGACT
TGCCGTAAACCGGAACCGGGTGAAACGGGTGCTGCGGGAAGTGTTTCGTGCCCGCCAGGAGGATATGGCGGGCCTTGATC
TGGTGATGCGTCTGCGTTGCCGTGCCAGCGATCGCAGTCCGGTGCAGTTGGCGGACGAAGCACGGCGTCTCATGATTCGA
TTGCAGCAATGTCGCGAATGA

Upstream 100 bases:

>100_bases
ACCCGGGGACCCTATTATTCGTTTTCCTAAAACTCATCGCCTGCATAAGGCAGAAGAATTTTCCTCGGTCATCCGGTTCA
GGTGTTCCATAGGCGGTGAA

Downstream 100 bases:

>100_bases
TTATTGCGTTTATCAGGCTCTATCAATACTGCCTGAGTCCTTTCCTTGGACCCTCATGCCGGTTCAGTCCGTCTTGTTCG
CATTACGCCTGTGAAGCGCT

Product: ribonuclease P protein component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5 [H]

Number of amino acids: Translated: 86; Mature: 86

Protein sequence:

>86_residues
MLQVFAKPNGLLHSRLGLIVAGKIERLAVNRNRVKRVLREVFRARQEDMAGLDLVMRLRCRASDRSPVQLADEARRLMIR
LQQCRE

Sequences:

>Translated_86_residues
MLQVFAKPNGLLHSRLGLIVAGKIERLAVNRNRVKRVLREVFRARQEDMAGLDLVMRLRCRASDRSPVQLADEARRLMIR
LQQCRE
>Mature_86_residues
MLQVFAKPNGLLHSRLGLIVAGKIERLAVNRNRVKRVLREVFRARQEDMAGLDLVMRLRCRASDRSPVQLADEARRLMIR
LQQCRE

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- ProDom:   PD003629 [H]

Pfam domain/function: PF00825 Ribonuclease_P [H]

EC number: =3.1.26.5 [H]

Molecular weight: Translated: 10009; Mature: 10009

Theoretical pI: Translated: 12.05; Mature: 12.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQVFAKPNGLLHSRLGLIVAGKIERLAVNRNRVKRVLREVFRARQEDMAGLDLVMRLRC
CCEEECCCCCHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RASDRSPVQLADEARRLMIRLQQCRE
CCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQVFAKPNGLLHSRLGLIVAGKIERLAVNRNRVKRVLREVFRARQEDMAGLDLVMRLRC
CCEEECCCCCHHHHHHHHHHHCHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RASDRSPVQLADEARRLMIRLQQCRE
CCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]