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The map label for this gene is oxaA

Identifier: 82703889

GI number: 82703889

Start: 3181656

End: 3183365

Strand: Reverse

Name: oxaA

Synonym: Nmul_A2776

Alternate gene names: 82703889

Gene position: 3183365-3181656 (Counterclockwise)

Preceding gene: 82703890

Following gene: 82703888

Centisome position: 99.97

GC content: 55.15

Gene sequence:

>1710_bases
ATGGATACACAAAGATTCGTACTCTTCCTGATTTTTGCCACATCGCTGTTATTCCTGTGGGATGCGTGGCAGAAAGAACA
ATATCCTGCAACCCAGGGGCCGAAAACGGCCGTGCAGGGCACAGAAACGCAGGCCAATACAGGTACTGCAGGTACCGCCG
AGACTCCGGTGCCAGGAGATCAGCTTGCTTCATCAGTTCCGCAAAGAGGCTCGACCGCGGAAAACGGTGCTCCTGTCAGG
GCGGCGGGCAAGCTGGAATCCGGGGATAAAATCACGATCAAGACCGACATGGTGCTGGCGGAAATCGACACCGCAGGGGG
CGATATTCGCCGCCTCGAGTTGCTGCATCAGCCTTCCAAGGAGGATAAAAACAAGCCTTTCGCATTACTGGAAAGCGATC
CCGAACGCGTCTACATAGCGCAATCCGGATTGATCGGTGAAGGTTTACCGACCCACAAGACGCGTTTTACGGCGGAGCCG
GGTGCATACGAGCTGGCAGCCGGGCAGGATAAAATCCAGATACGGTTGAGCGCGCCGGAGGTCGACGGCGTACAAGTGAC
TAAAATATACACGTTTCATCGGGGGAGCTATCTCATCGATGTGAGTTTCGAGGTCGCCAATCAACGGAACGCCGCCATCC
AGCCGTTTTCCTACTTCCAGATGCTGCGCGACAGCCGGCCTCCCGTGGGTTCGTTCTTCATGGTCCCAACCTATACCGGG
GCGGCGCTTTATACTGAAGAGGAAAAATTCAGGAAGATCGAGTTTTCCGCGCTGGACAAGGGCAATGCCAGCTATCCCAA
GAATGCGGACAACGGCTGGATTGCCATGCTGCAGCAGTACTTCCTCGCCGCCTGGCTACCCAAGGACAAGCTGCCGCGTG
AATATTACGCGAAACGTCTTGGAGAAAACGAATATACCGCCGGTGTAATCGTACCGGTAGGCCAGATAGAACCCGGCAGT
AGCGCCACTGTCACGGTCCCGCTCTATGCGGGACCGGAAGAGCAAAGCAAGCTTGCGTCGATCGCGCCGGGTCTCGATCT
CGTTGTCGATTACGGCTGGTTGACGGTGATCGGCGCGCCATTGTTCTGGCTGTTGTCGTTGTTTCACTCCTGGACTGGAA
ATTGGGGAGTGGCAATCATCCTCCTCACCATGTCGGTCAAGCTTGCATTCTTTCCCCTGTCTGCGGCAGGTTACCGCTCG
ATGGCGAAGTTGCGTTTAGTGACGCCCAAGCTCCAGCGTTTGCGGGAGCAACACGGGAATGACCGGCAGCGCATGCACCA
GGCCATGATGGATTTTTATAAAACGGAAAAAATCAACCCGATGGGAGGCTGTTTGCCCATCCTGGTGCAGATTCCGGTAT
TCATTTCGCTGTACTGGGTACTGCTCTCGAGCGTGGAATTGCGCTACGCGTCTTTTGCGTTGTGGATAGAGGATCTTTCC
GCACCCGATCCCTATTATGTGCTGCCGGTAATCATGGGTATTTCCATGTTCCTGCAACAGCGGCTCAGCCCCCCGGCGAC
CGATCCCATCCAGGCGAGAGTTATGCAGATCATGCCTTTGGCATTCAGCGTTTTCTTTTTCTTCTTCCCCGCAGGCCTGG
TGCTGTATTCCCTGGTAAACAACGTGCTTTCCATCGCGCAGCAGTGGCAGATCACGCGCATGATCGAAGGTTCGGCCGCA
AATACGAGCAAGCAGAAGAAAGCAAATTAG

Upstream 100 bases:

>100_bases
CTGGAGCCGGGGAGGATATGACCCCGTTCCTGCGGAACCCTTCCGTTGAATGTTTCTGGACGGTTTTTATCTGTCGTAAA
AAAATAACTCGCAGAGCAAG

Downstream 100 bases:

>100_bases
TGATCAGGGGAATTGCCGGACCCGACTCCCCTCTCTTCCCGTCTTCATAAGCGAGGTTGGCATTCGAACTCAGGATGACC
CGTTCTGATGTGATTGCCGC

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MDTQRFVLFLIFATSLLFLWDAWQKEQYPATQGPKTAVQGTETQANTGTAGTAETPVPGDQLASSVPQRGSTAENGAPVR
AAGKLESGDKITIKTDMVLAEIDTAGGDIRRLELLHQPSKEDKNKPFALLESDPERVYIAQSGLIGEGLPTHKTRFTAEP
GAYELAAGQDKIQIRLSAPEVDGVQVTKIYTFHRGSYLIDVSFEVANQRNAAIQPFSYFQMLRDSRPPVGSFFMVPTYTG
AALYTEEEKFRKIEFSALDKGNASYPKNADNGWIAMLQQYFLAAWLPKDKLPREYYAKRLGENEYTAGVIVPVGQIEPGS
SATVTVPLYAGPEEQSKLASIAPGLDLVVDYGWLTVIGAPLFWLLSLFHSWTGNWGVAIILLTMSVKLAFFPLSAAGYRS
MAKLRLVTPKLQRLREQHGNDRQRMHQAMMDFYKTEKINPMGGCLPILVQIPVFISLYWVLLSSVELRYASFALWIEDLS
APDPYYVLPVIMGISMFLQQRLSPPATDPIQARVMQIMPLAFSVFFFFFPAGLVLYSLVNNVLSIAQQWQITRMIEGSAA
NTSKQKKAN

Sequences:

>Translated_569_residues
MDTQRFVLFLIFATSLLFLWDAWQKEQYPATQGPKTAVQGTETQANTGTAGTAETPVPGDQLASSVPQRGSTAENGAPVR
AAGKLESGDKITIKTDMVLAEIDTAGGDIRRLELLHQPSKEDKNKPFALLESDPERVYIAQSGLIGEGLPTHKTRFTAEP
GAYELAAGQDKIQIRLSAPEVDGVQVTKIYTFHRGSYLIDVSFEVANQRNAAIQPFSYFQMLRDSRPPVGSFFMVPTYTG
AALYTEEEKFRKIEFSALDKGNASYPKNADNGWIAMLQQYFLAAWLPKDKLPREYYAKRLGENEYTAGVIVPVGQIEPGS
SATVTVPLYAGPEEQSKLASIAPGLDLVVDYGWLTVIGAPLFWLLSLFHSWTGNWGVAIILLTMSVKLAFFPLSAAGYRS
MAKLRLVTPKLQRLREQHGNDRQRMHQAMMDFYKTEKINPMGGCLPILVQIPVFISLYWVLLSSVELRYASFALWIEDLS
APDPYYVLPVIMGISMFLQQRLSPPATDPIQARVMQIMPLAFSVFFFFFPAGLVLYSLVNNVLSIAQQWQITRMIEGSAA
NTSKQKKAN
>Mature_569_residues
MDTQRFVLFLIFATSLLFLWDAWQKEQYPATQGPKTAVQGTETQANTGTAGTAETPVPGDQLASSVPQRGSTAENGAPVR
AAGKLESGDKITIKTDMVLAEIDTAGGDIRRLELLHQPSKEDKNKPFALLESDPERVYIAQSGLIGEGLPTHKTRFTAEP
GAYELAAGQDKIQIRLSAPEVDGVQVTKIYTFHRGSYLIDVSFEVANQRNAAIQPFSYFQMLRDSRPPVGSFFMVPTYTG
AALYTEEEKFRKIEFSALDKGNASYPKNADNGWIAMLQQYFLAAWLPKDKLPREYYAKRLGENEYTAGVIVPVGQIEPGS
SATVTVPLYAGPEEQSKLASIAPGLDLVVDYGWLTVIGAPLFWLLSLFHSWTGNWGVAIILLTMSVKLAFFPLSAAGYRS
MAKLRLVTPKLQRLREQHGNDRQRMHQAMMDFYKTEKINPMGGCLPILVQIPVFISLYWVLLSSVELRYASFALWIEDLS
APDPYYVLPVIMGISMFLQQRLSPPATDPIQARVMQIMPLAFSVFFFFFPAGLVLYSLVNNVLSIAQQWQITRMIEGSAA
NTSKQKKAN

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=510, Percent_Identity=41.5686274509804, Blast_Score=420, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24662345, Length=200, Percent_Identity=28.5, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356443, Length=200, Percent_Identity=28.5, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_NITMU (Q2Y5A8)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_413455.1
- ProteinModelPortal:   Q2Y5A8
- SMR:   Q2Y5A8
- STRING:   Q2Y5A8
- GeneID:   3785626
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A2776
- eggNOG:   COG0706
- HOGENOM:   HBG507812
- OMA:   TYRGAAF
- PhylomeDB:   Q2Y5A8
- ProtClustDB:   CLSK585296
- BioCyc:   NMUL323848:NMUL_A2776-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03593
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 63210; Mature: 63210

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x151f2cf8)-; HASH(0x126891c4)-; HASH(0x15e44d70)-; HASH(0x15e5c0a4)-; HASH(0x1632a3fc)-; HASH(0x1634e4a8)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQRFVLFLIFATSLLFLWDAWQKEQYPATQGPKTAVQGTETQANTGTAGTAETPVPGD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QLASSVPQRGSTAENGAPVRAAGKLESGDKITIKTDMVLAEIDTAGGDIRRLELLHQPSK
HHHHHCCCCCCCCCCCCCEEECCCCCCCCEEEEEECEEEEEECCCCCCHHHHHHHHCCCC
EDKNKPFALLESDPERVYIAQSGLIGEGLPTHKTRFTAEPGAYELAAGQDKIQIRLSAPE
CCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCEECCCCCCEEEECCCCEEEEEEECCC
VDGVQVTKIYTFHRGSYLIDVSFEVANQRNAAIQPFSYFQMLRDSRPPVGSFFMVPTYTG
CCCEEEEEEEEEECCCEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCC
AALYTEEEKFRKIEFSALDKGNASYPKNADNGWIAMLQQYFLAAWLPKDKLPREYYAKRL
CEEEECHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHC
GENEYTAGVIVPVGQIEPGSSATVTVPLYAGPEEQSKLASIAPGLDLVVDYGWLTVIGAP
CCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEECHHHHHHHHH
LFWLLSLFHSWTGNWGVAIILLTMSVKLAFFPLSAAGYRSMAKLRLVTPKLQRLREQHGN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHEECCHHHHHHHHHCCC
DRQRMHQAMMDFYKTEKINPMGGCLPILVQIPVFISLYWVLLSSVELRYASFALWIEDLS
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APDPYYVLPVIMGISMFLQQRLSPPATDPIQARVMQIMPLAFSVFFFFFPAGLVLYSLVN
CCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVLSIAQQWQITRMIEGSAANTSKQKKAN
HHHHHHHHHHHHHHCCCCCCCCCHHCCCH
>Mature Secondary Structure
MDTQRFVLFLIFATSLLFLWDAWQKEQYPATQGPKTAVQGTETQANTGTAGTAETPVPGD
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QLASSVPQRGSTAENGAPVRAAGKLESGDKITIKTDMVLAEIDTAGGDIRRLELLHQPSK
HHHHHCCCCCCCCCCCCCEEECCCCCCCCEEEEEECEEEEEECCCCCCHHHHHHHHCCCC
EDKNKPFALLESDPERVYIAQSGLIGEGLPTHKTRFTAEPGAYELAAGQDKIQIRLSAPE
CCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCEECCCCCCEEEECCCCEEEEEEECCC
VDGVQVTKIYTFHRGSYLIDVSFEVANQRNAAIQPFSYFQMLRDSRPPVGSFFMVPTYTG
CCCEEEEEEEEEECCCEEEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCC
AALYTEEEKFRKIEFSALDKGNASYPKNADNGWIAMLQQYFLAAWLPKDKLPREYYAKRL
CEEEECHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHC
GENEYTAGVIVPVGQIEPGSSATVTVPLYAGPEEQSKLASIAPGLDLVVDYGWLTVIGAP
CCCCCCCEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEECHHHHHHHHH
LFWLLSLFHSWTGNWGVAIILLTMSVKLAFFPLSAAGYRSMAKLRLVTPKLQRLREQHGN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHEECCHHHHHHHHHCCC
DRQRMHQAMMDFYKTEKINPMGGCLPILVQIPVFISLYWVLLSSVELRYASFALWIEDLS
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
APDPYYVLPVIMGISMFLQQRLSPPATDPIQARVMQIMPLAFSVFFFFFPAGLVLYSLVN
CCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVLSIAQQWQITRMIEGSAANTSKQKKAN
HHHHHHHHHHHHHHCCCCCCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA