Click here to switch to the map view.

The map label for this gene is pilC [H]

Identifier: 82703704

GI number: 82703704

Start: 2974975

End: 2976159

Strand: Reverse

Name: pilC [H]

Synonym: Nmul_A2589

Alternate gene names: 82703704

Gene position: 2976159-2974975 (Counterclockwise)

Preceding gene: 82703705

Following gene: 82703703

Centisome position: 93.47

GC content: 56.46

Gene sequence:

>1185_bases
ATGCGTTATGAGGTAAAAGCTGTGCTCGCCGGACGAGGCGCAGTACTTCTGGAACTCGAAGCCGATAGCGAGGAGGATGC
CCGTCTCCAGATCGCCGCGCAGGGGGGAATGGTCCTGCATGTCAGGCGCAGATTTACAGGCTGGATGCCCAAGCCGAAAT
CGCGCTTTCCGCTGGCGCATTTCAGTCAGGAGTTGCTTTCCCTGCTGGTCGCCGGGCTCAGTCTGGTGGAAAGTATCGAG
ACACTGGCTGACAAAGAGCAGGATAATGGCACGCGCAAGATTATTGAAGGGCTTCTTGCGCGGCTCTACGAAGGCGTAAC
CCTTTCACGGGCACTCGAATCTTTTCCCCAGGCTTTCCCACCGCTCTATATCGCTACTGCGCGCGCGAGCGAACGTACGG
GTGATCTGCCCGAAGCGTTGACGCGTTTCATCGCTTATCAGACGCAGATGGATCTGGTTCGAAAGAAGCTGATCGGTGCA
TCCATCTACCCCGTTCTCCTCCTGATAATCGGATTGCTGGTTGCTATCTTCCTGCTGATTTTTGTAGTACCGAAATTCAG
CGCCATTTACGAAGATACCGGAGCGGACCTGCCCTTTCTTTCCGTGCTACTGATTCGATGGGGGCATTTCGTGCATGAGC
AAGGGGGGCAGCTGGCAGTTCTTGTGGCGGCGGTCTCCAGCATCATCCTGTACGGGGTCACACGTCCTTCTTTCAAGATG
CATGCGGCACAGCAGTTATGGCGCATTCCGGCCATCGGGGAACGCATGCGCGTTTACCAGCTTGCGCGTTTTTACCGGAC
ACTGGGCATGTTGTTGCGCGGGGGCATTCCGATTGCAAAAGCCCTGGAAATGGTTACCGGCCTGCTTCAGCCGCACTTTC
GGCCAAAGGTCGAGGCAGCGGCGGTTCTTATCCGTGAAGGAAAACCCATTTCCAGCGCGATGGAAGCGCAAGGGTTGACC
ACCGCAGTGGGAAACCGGATGCTGAGAGTCGGCGAGAGAACCGGCCTCATGGGTGAAATGATGGAGCGGATCGGCAACTT
TCATGATGAAGAAATTGCGCGGTGGGTCGAATGGCTGACGAAGCTGATCGAACCGGTGTTGATGGCCGTGATCGGCGCAG
TCATCGGCGGGATCATCATCCTCATGTATATGCCCATCTTTCAGCTGGCGGGAAGCGTGGGTTGA

Upstream 100 bases:

>100_bases
TCCCGGTGAACATGGGGAGTACGACCTGTTTTCCTACGGCAAGGACGGTCAACCCGGGGGTACAGGTGAAGCAGCCGACA
TTACGAACTGGTAGGCTGCA

Downstream 100 bases:

>100_bases
GCCTATTGCCGTCCCCCGGTTACCCGTGAAGATGCGTTGCTTCTGCTGAGGAGAAAGCATCCTTAAGTCATGGGATTTCC
CTGTTTTGCTGCGCAATCGA

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRYEVKAVLAGRGAVLLELEADSEEDARLQIAAQGGMVLHVRRRFTGWMPKPKSRFPLAHFSQELLSLLVAGLSLVESIE
TLADKEQDNGTRKIIEGLLARLYEGVTLSRALESFPQAFPPLYIATARASERTGDLPEALTRFIAYQTQMDLVRKKLIGA
SIYPVLLLIIGLLVAIFLLIFVVPKFSAIYEDTGADLPFLSVLLIRWGHFVHEQGGQLAVLVAAVSSIILYGVTRPSFKM
HAAQQLWRIPAIGERMRVYQLARFYRTLGMLLRGGIPIAKALEMVTGLLQPHFRPKVEAAAVLIREGKPISSAMEAQGLT
TAVGNRMLRVGERTGLMGEMMERIGNFHDEEIARWVEWLTKLIEPVLMAVIGAVIGGIIILMYMPIFQLAGSVG

Sequences:

>Translated_394_residues
MRYEVKAVLAGRGAVLLELEADSEEDARLQIAAQGGMVLHVRRRFTGWMPKPKSRFPLAHFSQELLSLLVAGLSLVESIE
TLADKEQDNGTRKIIEGLLARLYEGVTLSRALESFPQAFPPLYIATARASERTGDLPEALTRFIAYQTQMDLVRKKLIGA
SIYPVLLLIIGLLVAIFLLIFVVPKFSAIYEDTGADLPFLSVLLIRWGHFVHEQGGQLAVLVAAVSSIILYGVTRPSFKM
HAAQQLWRIPAIGERMRVYQLARFYRTLGMLLRGGIPIAKALEMVTGLLQPHFRPKVEAAAVLIREGKPISSAMEAQGLT
TAVGNRMLRVGERTGLMGEMMERIGNFHDEEIARWVEWLTKLIEPVLMAVIGAVIGGIIILMYMPIFQLAGSVG
>Mature_394_residues
MRYEVKAVLAGRGAVLLELEADSEEDARLQIAAQGGMVLHVRRRFTGWMPKPKSRFPLAHFSQELLSLLVAGLSLVESIE
TLADKEQDNGTRKIIEGLLARLYEGVTLSRALESFPQAFPPLYIATARASERTGDLPEALTRFIAYQTQMDLVRKKLIGA
SIYPVLLLIIGLLVAIFLLIFVVPKFSAIYEDTGADLPFLSVLLIRWGHFVHEQGGQLAVLVAAVSSIILYGVTRPSFKM
HAAQQLWRIPAIGERMRVYQLARFYRTLGMLLRGGIPIAKALEMVTGLLQPHFRPKVEAAAVLIREGKPISSAMEAQGLT
TAVGNRMLRVGERTGLMGEMMERIGNFHDEEIARWVEWLTKLIEPVLMAVIGAVIGGIIILMYMPIFQLAGSVG

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1786295, Length=335, Percent_Identity=28.0597014925373, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1789724, Length=382, Percent_Identity=25.130890052356, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 43599; Mature: 43599

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYEVKAVLAGRGAVLLELEADSEEDARLQIAAQGGMVLHVRRRFTGWMPKPKSRFPLAH
CCEEEEEHEECCCEEEEEEECCCCCCCEEEEEECCCEEEEEHHHHCCCCCCCCCCCCHHH
FSQELLSLLVAGLSLVESIETLADKEQDNGTRKIIEGLLARLYEGVTLSRALESFPQAFP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
PLYIATARASERTGDLPEALTRFIAYQTQMDLVRKKLIGASIYPVLLLIIGLLVAIFLLI
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FVVPKFSAIYEDTGADLPFLSVLLIRWGHFVHEQGGQLAVLVAAVSSIILYGVTRPSFKM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHH
HAAQQLWRIPAIGERMRVYQLARFYRTLGMLLRGGIPIAKALEMVTGLLQPHFRPKVEAA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHH
AVLIREGKPISSAMEAQGLTTAVGNRMLRVGERTGLMGEMMERIGNFHDEEIARWVEWLT
HHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHH
KLIEPVLMAVIGAVIGGIIILMYMPIFQLAGSVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRYEVKAVLAGRGAVLLELEADSEEDARLQIAAQGGMVLHVRRRFTGWMPKPKSRFPLAH
CCEEEEEHEECCCEEEEEEECCCCCCCEEEEEECCCEEEEEHHHHCCCCCCCCCCCCHHH
FSQELLSLLVAGLSLVESIETLADKEQDNGTRKIIEGLLARLYEGVTLSRALESFPQAFP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
PLYIATARASERTGDLPEALTRFIAYQTQMDLVRKKLIGASIYPVLLLIIGLLVAIFLLI
CCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
FVVPKFSAIYEDTGADLPFLSVLLIRWGHFVHEQGGQLAVLVAAVSSIILYGVTRPSFKM
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHH
HAAQQLWRIPAIGERMRVYQLARFYRTLGMLLRGGIPIAKALEMVTGLLQPHFRPKVEAA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHH
AVLIREGKPISSAMEAQGLTTAVGNRMLRVGERTGLMGEMMERIGNFHDEEIARWVEWLT
HHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHH
KLIEPVLMAVIGAVIGGIIILMYMPIFQLAGSVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]