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The map label for this gene is tolQ [H]

Identifier: 82703685

GI number: 82703685

Start: 2941867

End: 2943522

Strand: Reverse

Name: tolQ [H]

Synonym: Nmul_A2570

Alternate gene names: 82703685

Gene position: 2943522-2941867 (Counterclockwise)

Preceding gene: 82703690

Following gene: 82703684

Centisome position: 92.44

GC content: 56.04

Gene sequence:

>1656_bases
ATGCGTTTCCTGCCGTTTCTGCTCGCTTTTGTATTGTCGACGTGGTCTTTTTCCAGTCATGCGTGGTGGAATGAGGACTG
GACAAGCCGCAAAAAAATAACGCTGGCCGCCCCATCAGGCGAGGTAGCGGATGTGCCCGTATTAATCCGCCTGCATACAG
GCAACTTCGATTTTTTCTCGGCAAGCGATAATGGCGGTGATGTGCGGCTGGTCGCAGGAGATGACAAGACCGAACTCAAG
TTCCATTTTGAAAAATGGGATGTCGCAAACGAGCTGGCGCTCATCTGGGTGAAAGTACCCAGACTCTCGGCCCAAACCGA
AATTTTCCTTTACTACGGTAATGAAAATGCGACATCGGCAGCCGACCCCAAAGGGACGTACGATGCCGGCAGTGCGATCT
ATCATTTTGCCGAACCCCAGGGAAACCCTCAGGATAGCGGCTCCAACAATCTGCATGCACAGTCCCCTGCGCAACATGTG
GCAGCCTCATTTTCGAATGGCGGCGCAGGATTCGATGGCACCCAAAGCGTGATTCTCCCCACGATACAGGCGTCAGGGGG
TTACAGCTTCAGCATATGGGTCAAGCCCGCCTCCCTTAGCGGCACCATTTATCAGTCCGATAACGTGAGCGTCTCCCTTG
ATGGCGGTCTGATCCGGGCACAGGCAGGCGGAGCGGGCGTGATTTCCGACAAACCTCTCAGCGCGGGACAGTGGCATCAC
ATCGGTTTCACGATTTCGGATGCACTGCGTATATATATAGCCGGCAAGGCGGCTGGCGAAGCGCGGAATGCGGTATTGCC
TGCGGGCAGCGTGACGCTGGGAGGGAAATTCAAGGGCGAGATGGACGAAGCGCAGGTGTCGGGGCTGGTGCGGGGGGCCG
AATGGATTGCGGTTCAGGCTGCTCTGGGGCCGGACGGCAAGCTGGTTGTGATGGGTGAAGAAGAGACCATCGAAGGCGGC
TCCGAGGCCTCGCACATGGGCATCATCCTGAAATCGCTGACCGTGGATGGATGGGTTGCGATTGGTCTCCTGACGGTGAT
GCTGCTGATTGCGATATGGGTAATGTACAGCAAGGCGGTCTACATCAATCGCGTGGATAAGTCCAACAACCGCTTCATGG
ACAAATTCCGCGAGCTGTCAACCGATCTGGCCATGATAGACAAAGCCCAGGGGTTGGGAAAAGACTTCGAGCATTCCTCT
CTTTATCGAATCTATCACATTGGCGCGGTTGAACTGGCGCATCGTTTCCAGGATACGGATGCCGCGCATACCGACAAGTC
TTTGACACCCCAATCACTCGATGCCATCCGTGCAAGCCTGGATGCCGGGCTGGTGGAAGAAATCCAGCGTATGAACAGAT
TCATGGTGCTGCTGACCATTGCCATTTCCGGCGGCCCTTTCATTGGCCTCTTGGGAACCGTGATGGGGGTAATGATCACC
TTTGCGGCCATTGCCGCCGCCGGGGACGTCAATGTCAACGCCATTGCGCCTGGCATCGCCGCCGCCCTTGCGGCAACCGT
CGCAGGCATGGGTGTGGCGATTCCATCCCTCTTTGGCTACAACTATCTCGCCTCGCGCATCAAGGCCATAGTATCCAGGA
TGCATATTTTCGTGGACGAGTTCATCACCAAGCTTGCCGAAAACTACAGCCGCTGA

Upstream 100 bases:

>100_bases
TCCCAGGGCAGTCGCATGATCCGTTCGGATCATGATTCATTACCAATGGCTGTAATCAGAGGCAGGGATAATGCCCCCGT
GTTTATTGGGGTTAATTTGC

Downstream 100 bases:

>100_bases
CGGATTGACATGAAAGTTCAGGAAGAAAACGAGCTTTACGACGAAATCAATGTCGTTCCCATGCTGGATCTCGCCTATGT
CTTGCTGGTGATTTTCATCA

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MRFLPFLLAFVLSTWSFSSHAWWNEDWTSRKKITLAAPSGEVADVPVLIRLHTGNFDFFSASDNGGDVRLVAGDDKTELK
FHFEKWDVANELALIWVKVPRLSAQTEIFLYYGNENATSAADPKGTYDAGSAIYHFAEPQGNPQDSGSNNLHAQSPAQHV
AASFSNGGAGFDGTQSVILPTIQASGGYSFSIWVKPASLSGTIYQSDNVSVSLDGGLIRAQAGGAGVISDKPLSAGQWHH
IGFTISDALRIYIAGKAAGEARNAVLPAGSVTLGGKFKGEMDEAQVSGLVRGAEWIAVQAALGPDGKLVVMGEEETIEGG
SEASHMGIILKSLTVDGWVAIGLLTVMLLIAIWVMYSKAVYINRVDKSNNRFMDKFRELSTDLAMIDKAQGLGKDFEHSS
LYRIYHIGAVELAHRFQDTDAAHTDKSLTPQSLDAIRASLDAGLVEEIQRMNRFMVLLTIAISGGPFIGLLGTVMGVMIT
FAAIAAAGDVNVNAIAPGIAAALAATVAGMGVAIPSLFGYNYLASRIKAIVSRMHIFVDEFITKLAENYSR

Sequences:

>Translated_551_residues
MRFLPFLLAFVLSTWSFSSHAWWNEDWTSRKKITLAAPSGEVADVPVLIRLHTGNFDFFSASDNGGDVRLVAGDDKTELK
FHFEKWDVANELALIWVKVPRLSAQTEIFLYYGNENATSAADPKGTYDAGSAIYHFAEPQGNPQDSGSNNLHAQSPAQHV
AASFSNGGAGFDGTQSVILPTIQASGGYSFSIWVKPASLSGTIYQSDNVSVSLDGGLIRAQAGGAGVISDKPLSAGQWHH
IGFTISDALRIYIAGKAAGEARNAVLPAGSVTLGGKFKGEMDEAQVSGLVRGAEWIAVQAALGPDGKLVVMGEEETIEGG
SEASHMGIILKSLTVDGWVAIGLLTVMLLIAIWVMYSKAVYINRVDKSNNRFMDKFRELSTDLAMIDKAQGLGKDFEHSS
LYRIYHIGAVELAHRFQDTDAAHTDKSLTPQSLDAIRASLDAGLVEEIQRMNRFMVLLTIAISGGPFIGLLGTVMGVMIT
FAAIAAAGDVNVNAIAPGIAAALAATVAGMGVAIPSLFGYNYLASRIKAIVSRMHIFVDEFITKLAENYSR
>Mature_551_residues
MRFLPFLLAFVLSTWSFSSHAWWNEDWTSRKKITLAAPSGEVADVPVLIRLHTGNFDFFSASDNGGDVRLVAGDDKTELK
FHFEKWDVANELALIWVKVPRLSAQTEIFLYYGNENATSAADPKGTYDAGSAIYHFAEPQGNPQDSGSNNLHAQSPAQHV
AASFSNGGAGFDGTQSVILPTIQASGGYSFSIWVKPASLSGTIYQSDNVSVSLDGGLIRAQAGGAGVISDKPLSAGQWHH
IGFTISDALRIYIAGKAAGEARNAVLPAGSVTLGGKFKGEMDEAQVSGLVRGAEWIAVQAALGPDGKLVVMGEEETIEGG
SEASHMGIILKSLTVDGWVAIGLLTVMLLIAIWVMYSKAVYINRVDKSNNRFMDKFRELSTDLAMIDKAQGLGKDFEHSS
LYRIYHIGAVELAHRFQDTDAAHTDKSLTPQSLDAIRASLDAGLVEEIQRMNRFMVLLTIAISGGPFIGLLGTVMGVMIT
FAAIAAAGDVNVNAIAPGIAAALAATVAGMGVAIPSLFGYNYLASRIKAIVSRMHIFVDEFITKLAENYSR

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=131, Percent_Identity=32.0610687022901, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 58942; Mature: 58942

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLPFLLAFVLSTWSFSSHAWWNEDWTSRKKITLAAPSGEVADVPVLIRLHTGNFDFFS
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEE
ASDNGGDVRLVAGDDKTELKFHFEKWDVANELALIWVKVPRLSAQTEIFLYYGNENATSA
CCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCC
ADPKGTYDAGSAIYHFAEPQGNPQDSGSNNLHAQSPAQHVAASFSNGGAGFDGTQSVILP
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEE
TIQASGGYSFSIWVKPASLSGTIYQSDNVSVSLDGGLIRAQAGGAGVISDKPLSAGQWHH
EEECCCCEEEEEEEEECCCCCEEEECCCEEEEECCCEEEECCCCCCCCCCCCCCCCCEEE
IGFTISDALRIYIAGKAAGEARNAVLPAGSVTLGGKFKGEMDEAQVSGLVRGAEWIAVQA
EEEEECCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCEEEEEEE
ALGPDGKLVVMGEEETIEGGSEASHMGIILKSLTVDGWVAIGLLTVMLLIAIWVMYSKAV
EECCCCEEEEECCCCCCCCCCCCHHHEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHCEE
YINRVDKSNNRFMDKFRELSTDLAMIDKAQGLGKDFEHSSLYRIYHIGAVELAHRFQDTD
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHHHHHCCCC
AAHTDKSLTPQSLDAIRASLDAGLVEEIQRMNRFMVLLTIAISGGPFIGLLGTVMGVMIT
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHH
FAAIAAAGDVNVNAIAPGIAAALAATVAGMGVAIPSLFGYNYLASRIKAIVSRMHIFVDE
HHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FITKLAENYSR
HHHHHHHHCCC
>Mature Secondary Structure
MRFLPFLLAFVLSTWSFSSHAWWNEDWTSRKKITLAAPSGEVADVPVLIRLHTGNFDFFS
CCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEECCCEEEEE
ASDNGGDVRLVAGDDKTELKFHFEKWDVANELALIWVKVPRLSAQTEIFLYYGNENATSA
CCCCCCEEEEEECCCCCEEEEEEECCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCC
ADPKGTYDAGSAIYHFAEPQGNPQDSGSNNLHAQSPAQHVAASFSNGGAGFDGTQSVILP
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEE
TIQASGGYSFSIWVKPASLSGTIYQSDNVSVSLDGGLIRAQAGGAGVISDKPLSAGQWHH
EEECCCCEEEEEEEEECCCCCEEEECCCEEEEECCCEEEECCCCCCCCCCCCCCCCCEEE
IGFTISDALRIYIAGKAAGEARNAVLPAGSVTLGGKFKGEMDEAQVSGLVRGAEWIAVQA
EEEEECCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCEEEEEEE
ALGPDGKLVVMGEEETIEGGSEASHMGIILKSLTVDGWVAIGLLTVMLLIAIWVMYSKAV
EECCCCEEEEECCCCCCCCCCCCHHHEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHCEE
YINRVDKSNNRFMDKFRELSTDLAMIDKAQGLGKDFEHSSLYRIYHIGAVELAHRFQDTD
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEHHHHHHHHHCCCC
AAHTDKSLTPQSLDAIRASLDAGLVEEIQRMNRFMVLLTIAISGGPFIGLLGTVMGVMIT
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHH
FAAIAAAGDVNVNAIAPGIAAALAATVAGMGVAIPSLFGYNYLASRIKAIVSRMHIFVDE
HHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FITKLAENYSR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]