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The map label for this gene is lolC [H]

Identifier: 82703624

GI number: 82703624

Start: 2867723

End: 2868967

Strand: Reverse

Name: lolC [H]

Synonym: Nmul_A2509

Alternate gene names: 82703624

Gene position: 2868967-2867723 (Counterclockwise)

Preceding gene: 82703625

Following gene: 82703623

Centisome position: 90.1

GC content: 56.39

Gene sequence:

>1245_bases
GTGTCCTCGTACGAACTCTTCATCGGTTTGCGTTACACCCGCGCCAAGCGCCGCAATCACTTCATCTCGTTCATTTCCCT
CATTTCCTTGCTCGGTATTACGCTTGGGATGACAGCGCTCATTACCGTTATGTCGGTTATGAACGGATTTCAGAAGGAAG
TCCGCTCGCGCATCCTCGGTGTCGCGTCCCATATCCAGGTGAGCGGCGTGGAGGGTACGCTGACGGATTGGCGAAAAGTT
GCCGAAGAAGCGCGCAGGCATCCCGAGGTGGAGGCCGCTGCACCCTACATCAGCGCACAGGGGATGGTGTCGTTCGATCA
GGCCGTGAGCGGTGTGGCCGTGCGAGGCATCCTGCCTGGCATGGAGGATCACGTGGCAGATCTCGGACGGATGATGATAG
ACGGCAGACTGGAAAATCTGGCGCCGGGAGAGTTCGGTATAGTCATCGGCCGCGAGCTGGCACGCTCGCTGGGGGTTTTT
ACGGGTGACAGGATCGTATTGATCTCGCCACAGGGACAGGTGACGCCTGCAGGGATCATTCCGCGCCTCAAGCAGTTCAC
GATTATCGGGATATTCGAAGCGGGCCATTTCGAATACGACTCCGGGCTCGTGCTCATCCATCTGGCAGATGCACAAAAGC
TGTATCGCATGGAAAACCAGGTATCAGGCGTGCGCCTCAAGTTGCATGATCTTTTCAAGGCGCCGCAAGTCGCGCGTGAG
CTCGTGCCGCTGATTTCCAGCGATGTCTATATCAGCGACTGGACTCGCCAACACGCCAATTATTTTCGGGCCATACAGAT
CGAGAAACGCATGCTGTCTCTCATTCTTGCACTGATCATCGCAGTGGCGGCGTTCAATATTGTCTCCACATTGGTGATGG
CCGTGACGGACAAGCAATCGGATATTGCGATATTGCGCACCCTGGGTGCGAGTCCGCGCAGCATCATGAAAATCTTTATC
GTGCAGGGAACCTGGATCGGGGTGGTCGGTACCGCATTGGGGGTCATCGGCGGCGTGTTGCTTGCCTACAATGTGGAGGC
GGTCATTGCGATGATAGAGCGGTTGTTCAGCGTGCAGTTCCTGTCCAGCGAAGTCTACGTCATCAGCGAAATTCCCTCCG
ACCTCCAGTTCGATGACGTGATTGCCGTCGCCATCGTTTCCTTCGTGTTGACACTGCTGGCAACACTCTACCCGAGCTAT
CGCGCTTCAAAGATCAATCCGGCCGAGGCGCTGCGGTATGAGTGA

Upstream 100 bases:

>100_bases
GCGCGTGGGGTCTTTGACCGCAATGCTCAAGCTCTCCTGTTAACCCTGAGCAGAATGTGGCAAACTTCGCAGTTACGTCC
TAATCAGGCTATATCGATCC

Downstream 100 bases:

>100_bases
CAATATCATTTCCTGCCGCAACCTGCGGAAGAGCTATTATCAAGGCCAGATCGAGGTGCCGGTCCTGATGGGAATAGACC
TGAAGGTGGGAAAGGGAGAT

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSSYELFIGLRYTRAKRRNHFISFISLISLLGITLGMTALITVMSVMNGFQKEVRSRILGVASHIQVSGVEGTLTDWRKV
AEEARRHPEVEAAAPYISAQGMVSFDQAVSGVAVRGILPGMEDHVADLGRMMIDGRLENLAPGEFGIVIGRELARSLGVF
TGDRIVLISPQGQVTPAGIIPRLKQFTIIGIFEAGHFEYDSGLVLIHLADAQKLYRMENQVSGVRLKLHDLFKAPQVARE
LVPLISSDVYISDWTRQHANYFRAIQIEKRMLSLILALIIAVAAFNIVSTLVMAVTDKQSDIAILRTLGASPRSIMKIFI
VQGTWIGVVGTALGVIGGVLLAYNVEAVIAMIERLFSVQFLSSEVYVISEIPSDLQFDDVIAVAIVSFVLTLLATLYPSY
RASKINPAEALRYE

Sequences:

>Translated_414_residues
MSSYELFIGLRYTRAKRRNHFISFISLISLLGITLGMTALITVMSVMNGFQKEVRSRILGVASHIQVSGVEGTLTDWRKV
AEEARRHPEVEAAAPYISAQGMVSFDQAVSGVAVRGILPGMEDHVADLGRMMIDGRLENLAPGEFGIVIGRELARSLGVF
TGDRIVLISPQGQVTPAGIIPRLKQFTIIGIFEAGHFEYDSGLVLIHLADAQKLYRMENQVSGVRLKLHDLFKAPQVARE
LVPLISSDVYISDWTRQHANYFRAIQIEKRMLSLILALIIAVAAFNIVSTLVMAVTDKQSDIAILRTLGASPRSIMKIFI
VQGTWIGVVGTALGVIGGVLLAYNVEAVIAMIERLFSVQFLSSEVYVISEIPSDLQFDDVIAVAIVSFVLTLLATLYPSY
RASKINPAEALRYE
>Mature_413_residues
SSYELFIGLRYTRAKRRNHFISFISLISLLGITLGMTALITVMSVMNGFQKEVRSRILGVASHIQVSGVEGTLTDWRKVA
EEARRHPEVEAAAPYISAQGMVSFDQAVSGVAVRGILPGMEDHVADLGRMMIDGRLENLAPGEFGIVIGRELARSLGVFT
GDRIVLISPQGQVTPAGIIPRLKQFTIIGIFEAGHFEYDSGLVLIHLADAQKLYRMENQVSGVRLKLHDLFKAPQVAREL
VPLISSDVYISDWTRQHANYFRAIQIEKRMLSLILALIIAVAAFNIVSTLVMAVTDKQSDIAILRTLGASPRSIMKIFIV
QGTWIGVVGTALGVIGGVLLAYNVEAVIAMIERLFSVQFLSSEVYVISEIPSDLQFDDVIAVAIVSFVLTLLATLYPSYR
ASKINPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=407, Percent_Identity=38.0835380835381, Blast_Score=257, Evalue=8e-70,
Organism=Escherichia coli, GI1787360, Length=411, Percent_Identity=36.4963503649635, Blast_Score=231, Evalue=9e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45477; Mature: 45346

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSYELFIGLRYTRAKRRNHFISFISLISLLGITLGMTALITVMSVMNGFQKEVRSRILG
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASHIQVSGVEGTLTDWRKVAEEARRHPEVEAAAPYISAQGMVSFDQAVSGVAVRGILPG
HHHHEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHCCHHHHHCCCC
MEDHVADLGRMMIDGRLENLAPGEFGIVIGRELARSLGVFTGDRIVLISPQGQVTPAGII
HHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHH
PRLKQFTIIGIFEAGHFEYDSGLVLIHLADAQKLYRMENQVSGVRLKLHDLFKAPQVARE
HHHHHEEEEEEEECCCEEECCCEEEEEECCHHHHHHHHHHHCCCEEEHHHHHCCHHHHHH
LVPLISSDVYISDWTRQHANYFRAIQIEKRMLSLILALIIAVAAFNIVSTLVMAVTDKQS
HHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DIAILRTLGASPRSIMKIFIVQGTWIGVVGTALGVIGGVLLAYNVEAVIAMIERLFSVQF
CHHHHHHCCCCHHHHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSEVYVISEIPSDLQFDDVIAVAIVSFVLTLLATLYPSYRASKINPAEALRYE
HCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
SSYELFIGLRYTRAKRRNHFISFISLISLLGITLGMTALITVMSVMNGFQKEVRSRILG
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VASHIQVSGVEGTLTDWRKVAEEARRHPEVEAAAPYISAQGMVSFDQAVSGVAVRGILPG
HHHHEEEECCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHCCHHHHHCCCC
MEDHVADLGRMMIDGRLENLAPGEFGIVIGRELARSLGVFTGDRIVLISPQGQVTPAGII
HHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHH
PRLKQFTIIGIFEAGHFEYDSGLVLIHLADAQKLYRMENQVSGVRLKLHDLFKAPQVARE
HHHHHEEEEEEEECCCEEECCCEEEEEECCHHHHHHHHHHHCCCEEEHHHHHCCHHHHHH
LVPLISSDVYISDWTRQHANYFRAIQIEKRMLSLILALIIAVAAFNIVSTLVMAVTDKQS
HHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DIAILRTLGASPRSIMKIFIVQGTWIGVVGTALGVIGGVLLAYNVEAVIAMIERLFSVQF
CHHHHHHCCCCHHHHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSEVYVISEIPSDLQFDDVIAVAIVSFVLTLLATLYPSYRASKINPAEALRYE
HCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]