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The map label for this gene is ahpC [C]

Identifier: 82703429

GI number: 82703429

Start: 2630409

End: 2631047

Strand: Direct

Name: ahpC [C]

Synonym: Nmul_A2312

Alternate gene names: 82703429

Gene position: 2630409-2631047 (Clockwise)

Preceding gene: 82703428

Following gene: 82703431

Centisome position: 82.61

GC content: 51.8

Gene sequence:

>639_bases
ATGACCTTACGCTTAGGCGATACCGCCCCCGATTTCGAACAGGAATCCTCCATTGGCAGGATCAAATTTCACGAATGGAT
AGATGATTCCTGGGCAGTATTGTTTTCTCATCCCGCGGATTACACGCCAGTGTGCACAACCGAGCTGGGAATGACAGCCA
AGCTCAAGTCTGAATTCGACAAACGTAATGTGAAGGCGATCGGGTTGTCGGTGGATCCTGCGGCAAAACATACCGGATGG
ATCAAGGATATCGAGGAAACGCAAGGTTGTACCGTCGCTTTTCCCATTATTGCGGACGAAGACAGAAAGGTCGCGGCACT
ATATGACATGATTCACCCGAATCAGTCGGAAACCATGACAGTGCGCTCGCTTTTTGTGATCGACCCGAAGAAGAAAGTGC
GGCTTATCCTCACCTACCCCATGAGCACCGGACGCAATTTCGATGAGGTGCTGCGGGTGATCGATGCGCTGCAATTGACC
GATAACTATACGGTCGCCACCCCGGCCAACTGGAATGACGGCGGTGATGTGATTATCCCGCTGACTATCCAGGATGAGGC
AGTGATCAAGCAGAAGTTTCCGAAAGGCTATACCGCTCCACGTCCCTATCTGCGCATCACGCCCCAGCCGAATAAATAA

Upstream 100 bases:

>100_bases
GGACAGCAAACAATAGTTGTTGAGCGATTGCAGCAGGCAGGCTATATTGAACCGGTTTCCTACGAAATTCCCATCGATGT
TTTAACTCACGGAGAATGCC

Downstream 100 bases:

>100_bases
ACCCGGGCCCGAATAGTAGCATTGGCTGGCCGCCAAACACCGTTACCCTTATCAGGTGGAGCCCGGCTTACGGTATGCAG
CTCAGGAGTCCGCCTCTGCC

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTLRLGDTAPDFEQESSIGRIKFHEWIDDSWAVLFSHPADYTPVCTTELGMTAKLKSEFDKRNVKAIGLSVDPAAKHTGW
IKDIEETQGCTVAFPIIADEDRKVAALYDMIHPNQSETMTVRSLFVIDPKKKVRLILTYPMSTGRNFDEVLRVIDALQLT
DNYTVATPANWNDGGDVIIPLTIQDEAVIKQKFPKGYTAPRPYLRITPQPNK

Sequences:

>Translated_212_residues
MTLRLGDTAPDFEQESSIGRIKFHEWIDDSWAVLFSHPADYTPVCTTELGMTAKLKSEFDKRNVKAIGLSVDPAAKHTGW
IKDIEETQGCTVAFPIIADEDRKVAALYDMIHPNQSETMTVRSLFVIDPKKKVRLILTYPMSTGRNFDEVLRVIDALQLT
DNYTVATPANWNDGGDVIIPLTIQDEAVIKQKFPKGYTAPRPYLRITPQPNK
>Mature_211_residues
TLRLGDTAPDFEQESSIGRIKFHEWIDDSWAVLFSHPADYTPVCTTELGMTAKLKSEFDKRNVKAIGLSVDPAAKHTGWI
KDIEETQGCTVAFPIIADEDRKVAALYDMIHPNQSETMTVRSLFVIDPKKKVRLILTYPMSTGRNFDEVLRVIDALQLTD
NYTVATPANWNDGGDVIIPLTIQDEAVIKQKFPKGYTAPRPYLRITPQPNK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=221, Percent_Identity=49.7737556561086, Blast_Score=207, Evalue=6e-54,
Organism=Homo sapiens, GI32189392, Length=182, Percent_Identity=31.8681318681319, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI4505591, Length=195, Percent_Identity=31.2820512820513, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI32455266, Length=195, Percent_Identity=31.2820512820513, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI32455264, Length=195, Percent_Identity=31.2820512820513, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI5453549, Length=151, Percent_Identity=31.7880794701987, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI32483377, Length=151, Percent_Identity=27.1523178807947, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5802974, Length=166, Percent_Identity=27.1084337349398, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786822, Length=151, Percent_Identity=29.1390728476821, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=222, Percent_Identity=38.7387387387387, Blast_Score=156, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI193204376, Length=195, Percent_Identity=28.2051282051282, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32565831, Length=195, Percent_Identity=28.2051282051282, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17554494, Length=151, Percent_Identity=29.8013245033113, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319407, Length=213, Percent_Identity=55.3990610328638, Blast_Score=223, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323613, Length=189, Percent_Identity=26.984126984127, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320661, Length=185, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24581278, Length=218, Percent_Identity=49.5412844036697, Blast_Score=210, Evalue=7e-55,
Organism=Drosophila melanogaster, GI24652434, Length=205, Percent_Identity=50.7317073170732, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI17975518, Length=205, Percent_Identity=50.7317073170732, Blast_Score=191, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24652436, Length=206, Percent_Identity=50.4854368932039, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17157991, Length=150, Percent_Identity=34.6666666666667, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24641739, Length=150, Percent_Identity=34.6666666666667, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI17738015, Length=197, Percent_Identity=29.9492385786802, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24656348, Length=177, Percent_Identity=31.0734463276836, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17864676, Length=177, Percent_Identity=31.0734463276836, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21357347, Length=197, Percent_Identity=26.9035532994924, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23881; Mature: 23749

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRLGDTAPDFEQESSIGRIKFHEWIDDSWAVLFSHPADYTPVCTTELGMTAKLKSEFD
CEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEECCCCCEEHHHHHHC
KRNVKAIGLSVDPAAKHTGWIKDIEETQGCTVAFPIIADEDRKVAALYDMIHPNQSETMT
CCCEEEEEEECCCCCCCCCCHHHHHHCCCCEEEEEEEECCCCCEEEEHHHHCCCCCCEEE
VRSLFVIDPKKKVRLILTYPMSTGRNFDEVLRVIDALQLTDNYTVATPANWNDGGDVIIP
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEE
LTIQDEAVIKQKFPKGYTAPRPYLRITPQPNK
EEECCHHHHHHHCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure 
TLRLGDTAPDFEQESSIGRIKFHEWIDDSWAVLFSHPADYTPVCTTELGMTAKLKSEFD
EEECCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCEEECCCCCEEHHHHHHC
KRNVKAIGLSVDPAAKHTGWIKDIEETQGCTVAFPIIADEDRKVAALYDMIHPNQSETMT
CCCEEEEEEECCCCCCCCCCHHHHHHCCCCEEEEEEEECCCCCEEEEHHHHCCCCCCEEE
VRSLFVIDPKKKVRLILTYPMSTGRNFDEVLRVIDALQLTDNYTVATPANWNDGGDVIIP
EEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEE
LTIQDEAVIKQKFPKGYTAPRPYLRITPQPNK
EEECCHHHHHHHCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]