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The map label for this gene is mshA2 [H]

Identifier: 82702918

GI number: 82702918

Start: 2046334

End: 2048286

Strand: Reverse

Name: mshA2 [H]

Synonym: Nmul_A1795

Alternate gene names: 82702918

Gene position: 2048286-2046334 (Counterclockwise)

Preceding gene: 82702919

Following gene: 82702917

Centisome position: 64.33

GC content: 54.89

Gene sequence:

>1953_bases
ATGAAGAAGAGAATTGCCCTCATCAGTGAACACGCTTCACCCATCGCGGCAATAGGAGGTACGGACACCGGCGGACAAAA
TATAGCGGTGGCCGAGCTGGCCCGGCATCTTGCCGCCCTCGGCTACGAAATTGATGTCTTTACCCGCTGGGATGACCGCC
GTGTTCCAAAAATCCTCAACTGGCGGGATGGCATACGCATCGTCCATGTGGAAGCCGGGCCCGTCACGTTCATTCCCAAG
GAAAAGCTGCTGCCTTATATGCCCGCCTTCACGCGCGACATCCTGCGGTTTATCAAGTCGGAAAACAATCGCTACAAGCT
CGTTCACGCCCATTTCTTCATGTCCGGGCTGGTGGCGGCGGATATCAAGCGAAAACTGGGTATTCCTTTCATCGTTACCT
TTCACGCTCTCGCAAAAGTGCGGAGGCTTCACCAGGGAGGGAATGACTGGTTCCCGGACGAGGGCTTTGCCATCGAAGAA
AGGGTGATAACAGAAGCGGACCAGATTGTCGCCTTGTGCCCGCAGGACCGCGATGATCTGATCAATCTTTATGAAGCTGA
TCCCGGAAAAATCACGGTTATTCCAAACGGATTCAGACCGGATGAGATCTATCCTCTCGACAAGCTGTTCGCGCGCATGG
CGCTGAAACTCGATCCCAAGGAAAAGATTATCCTGCAACTGGGGCGCATGGTGCGGCGAAAGGGTGTCGATAACGTCATA
AAAGCGCTGGGCTACATGCGGCGCGAGCATAACTTCGAAGCACGTCTTCTGATAGTGGGCGGGGAGTCGGATGAGCCCGA
TCCAAAAACAACGCCTGAAATCGGTCGCCTGCAAAAACTGGCTGAAGCAGAGGGTGCGGGCGATCTTGTGACGTTTGTCG
GACGCCGCCCGCGCGACATGCTGCATTATTACTATAGCGCGTGCGACGTATTCACGACTACGCCCTGGTATGAACCGTTC
GGGATCACCCCGCTTGAAGCAATGGCCTGCGGGACGCCCGTGATCGGGTCAAATGTTGGGGGCATTAAATCCACCGTCAT
GGATGGCAGGACGGGCTTTCTCGTGCCGCCCAACGATCCCGCGTCACTCGGGCGCCGCATCATAGAGCTTTTGAGCAGCA
ACAAGCTCATGACGTATTTCAAGGAAAACGCCATCCGCCATGTCAATCAGAATTACACCTGGATGAAGGCAACGCATCTC
ACGGCCAACATGTACGAGCGGATTGCAACCCAGAGCCCCCTGCGAGCGGACGAAGAAGAAGATTCCTTGTCCTACATCGA
CGACTCCTTCGGGTCATTAATAGAGACTATTGAAAAGTCCAGGCGGAAAATCCGCCTTGCCATCCTCGATTCGGCCCAGG
CTGTATACCGCTCGTTGGCGCGCGGCGGAAAGGTATTGGTTTGCGGCAATGGCGGGAGTGCCGCCGAAGCGCAGCACTTT
GCGGCCGAACTCATGGGGCGGTTTGAGGCAAGTGGTCGTCGCGGCTTGCCCGCAATGGCACTCACTGCCGATACCGCCTT
TGTGACCGCCTGGTCGAATGACTATACATTTGACGATGTGTTTGCCAGACAGGTCGAAGCGCATGGGCAGCCGGGGGACG
TTCTGGTTGTCATCAGCTCGAGCGGGCAGTCAGTCAACTTGGTCAAGGCGCTCCGGACGGCGCGCCGGCACGAGATGTTC
TGCATTGGCCTGCTTGGCAAGGAGGGTGGTCCTGCCAGCGAACTGACTGATATCAACATCATTGTTCCGTCAAACGAAAC
TTCACGCATCCAGGAAGTACAACTGCTTGTTCTCCACGTGCTCAGTCATCTGATCGAGCAGCAAATCGTGGTGGATGACC
TGAATACCGTTCAGATAACGGAAGAGTGGTCAATAAAGCACTTTCAGGTCCAGGAAATGGCTAAAAACGTTAATAAGAGG
AAAATCAAGCATGAATCAACAAAGTGTGACTGA

Upstream 100 bases:

>100_bases
TCTGTTGTAACAGGGAGTGTTCCCGTGTGAATGAGGGGGCATTCTTCTGTTTCAGTACCGAGCGGCTTACTTTGGCCGGC
TTCAATGAAAGGGAAGGAGT

Downstream 100 bases:

>100_bases
CAAAGTCGTTATTGTCACGGGCGCAGGCCAGGGGTTGGGCGAGGCGATAGCAAACACGCTCGGCGCGGCAGGAGCGGTCG
TCTGCGCCTGCGATATCAAG

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase 2; GlcNAc-Ins-P N-acetylglucosaminyltransferase 2 [H]

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MKKRIALISEHASPIAAIGGTDTGGQNIAVAELARHLAALGYEIDVFTRWDDRRVPKILNWRDGIRIVHVEAGPVTFIPK
EKLLPYMPAFTRDILRFIKSENNRYKLVHAHFFMSGLVAADIKRKLGIPFIVTFHALAKVRRLHQGGNDWFPDEGFAIEE
RVITEADQIVALCPQDRDDLINLYEADPGKITVIPNGFRPDEIYPLDKLFARMALKLDPKEKIILQLGRMVRRKGVDNVI
KALGYMRREHNFEARLLIVGGESDEPDPKTTPEIGRLQKLAEAEGAGDLVTFVGRRPRDMLHYYYSACDVFTTTPWYEPF
GITPLEAMACGTPVIGSNVGGIKSTVMDGRTGFLVPPNDPASLGRRIIELLSSNKLMTYFKENAIRHVNQNYTWMKATHL
TANMYERIATQSPLRADEEEDSLSYIDDSFGSLIETIEKSRRKIRLAILDSAQAVYRSLARGGKVLVCGNGGSAAEAQHF
AAELMGRFEASGRRGLPAMALTADTAFVTAWSNDYTFDDVFARQVEAHGQPGDVLVVISSSGQSVNLVKALRTARRHEMF
CIGLLGKEGGPASELTDINIIVPSNETSRIQEVQLLVLHVLSHLIEQQIVVDDLNTVQITEEWSIKHFQVQEMAKNVNKR
KIKHESTKCD

Sequences:

>Translated_650_residues
MKKRIALISEHASPIAAIGGTDTGGQNIAVAELARHLAALGYEIDVFTRWDDRRVPKILNWRDGIRIVHVEAGPVTFIPK
EKLLPYMPAFTRDILRFIKSENNRYKLVHAHFFMSGLVAADIKRKLGIPFIVTFHALAKVRRLHQGGNDWFPDEGFAIEE
RVITEADQIVALCPQDRDDLINLYEADPGKITVIPNGFRPDEIYPLDKLFARMALKLDPKEKIILQLGRMVRRKGVDNVI
KALGYMRREHNFEARLLIVGGESDEPDPKTTPEIGRLQKLAEAEGAGDLVTFVGRRPRDMLHYYYSACDVFTTTPWYEPF
GITPLEAMACGTPVIGSNVGGIKSTVMDGRTGFLVPPNDPASLGRRIIELLSSNKLMTYFKENAIRHVNQNYTWMKATHL
TANMYERIATQSPLRADEEEDSLSYIDDSFGSLIETIEKSRRKIRLAILDSAQAVYRSLARGGKVLVCGNGGSAAEAQHF
AAELMGRFEASGRRGLPAMALTADTAFVTAWSNDYTFDDVFARQVEAHGQPGDVLVVISSSGQSVNLVKALRTARRHEMF
CIGLLGKEGGPASELTDINIIVPSNETSRIQEVQLLVLHVLSHLIEQQIVVDDLNTVQITEEWSIKHFQVQEMAKNVNKR
KIKHESTKCD
>Mature_650_residues
MKKRIALISEHASPIAAIGGTDTGGQNIAVAELARHLAALGYEIDVFTRWDDRRVPKILNWRDGIRIVHVEAGPVTFIPK
EKLLPYMPAFTRDILRFIKSENNRYKLVHAHFFMSGLVAADIKRKLGIPFIVTFHALAKVRRLHQGGNDWFPDEGFAIEE
RVITEADQIVALCPQDRDDLINLYEADPGKITVIPNGFRPDEIYPLDKLFARMALKLDPKEKIILQLGRMVRRKGVDNVI
KALGYMRREHNFEARLLIVGGESDEPDPKTTPEIGRLQKLAEAEGAGDLVTFVGRRPRDMLHYYYSACDVFTTTPWYEPF
GITPLEAMACGTPVIGSNVGGIKSTVMDGRTGFLVPPNDPASLGRRIIELLSSNKLMTYFKENAIRHVNQNYTWMKATHL
TANMYERIATQSPLRADEEEDSLSYIDDSFGSLIETIEKSRRKIRLAILDSAQAVYRSLARGGKVLVCGNGGSAAEAQHF
AAELMGRFEASGRRGLPAMALTADTAFVTAWSNDYTFDDVFARQVEAHGQPGDVLVVISSSGQSVNLVKALRTARRHEMF
CIGLLGKEGGPASELTDINIIVPSNETSRIQEVQLLVLHVLSHLIEQQIVVDDLNTVQITEEWSIKHFQVQEMAKNVNKR
KIKHESTKCD

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI14861836, Length=246, Percent_Identity=26.0162601626016, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786416, Length=165, Percent_Identity=46.0606060606061, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1789539, Length=187, Percent_Identity=40.6417112299465, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790061, Length=240, Percent_Identity=25.8333333333333, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI9755344, Length=404, Percent_Identity=22.029702970297, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 72668; Mature: 72668

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRIALISEHASPIAAIGGTDTGGQNIAVAELARHLAALGYEIDVFTRWDDRRVPKILN
CCCCEEHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHCC
WRDGIRIVHVEAGPVTFIPKEKLLPYMPAFTRDILRFIKSENNRYKLVHAHFFMSGLVAA
CCCCEEEEEEECCCEEECCHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
DIKRKLGIPFIVTFHALAKVRRLHQGGNDWFPDEGFAIEERVITEADQIVALCPQDRDDL
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCHH
INLYEADPGKITVIPNGFRPDEIYPLDKLFARMALKLDPKEKIILQLGRMVRRKGVDNVI
HHHEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHH
KALGYMRREHNFEARLLIVGGESDEPDPKTTPEIGRLQKLAEAEGAGDLVTFVGRRPRDM
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCHHH
LHYYYSACDVFTTTPWYEPFGITPLEAMACGTPVIGSNVGGIKSTVMDGRTGFLVPPNDP
HHHHHHHHHHEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEECCCCH
ASLGRRIIELLSSNKLMTYFKENAIRHVNQNYTWMKATHLTANMYERIATQSPLRADEEE
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCCC
DSLSYIDDSFGSLIETIEKSRRKIRLAILDSAQAVYRSLARGGKVLVCGNGGSAAEAQHF
CHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
AAELMGRFEASGRRGLPAMALTADTAFVTAWSNDYTFDDVFARQVEAHGQPGDVLVVISS
HHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECC
SGQSVNLVKALRTARRHEMFCIGLLGKEGGPASELTDINIIVPSNETSRIQEVQLLVLHV
CCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
LSHLIEQQIVVDDLNTVQITEEWSIKHFQVQEMAKNVNKRKIKHESTKCD
HHHHHHHHHHHCCCCEEEEECCCCCCCEEHHHHHHCHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKRIALISEHASPIAAIGGTDTGGQNIAVAELARHLAALGYEIDVFTRWDDRRVPKILN
CCCCEEHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCHHCC
WRDGIRIVHVEAGPVTFIPKEKLLPYMPAFTRDILRFIKSENNRYKLVHAHFFMSGLVAA
CCCCEEEEEEECCCEEECCHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHH
DIKRKLGIPFIVTFHALAKVRRLHQGGNDWFPDEGFAIEERVITEADQIVALCPQDRDDL
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCHH
INLYEADPGKITVIPNGFRPDEIYPLDKLFARMALKLDPKEKIILQLGRMVRRKGVDNVI
HHHEECCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHH
KALGYMRREHNFEARLLIVGGESDEPDPKTTPEIGRLQKLAEAEGAGDLVTFVGRRPRDM
HHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHCCCCHHH
LHYYYSACDVFTTTPWYEPFGITPLEAMACGTPVIGSNVGGIKSTVMDGRTGFLVPPNDP
HHHHHHHHHHEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHCCCCEEEECCCCH
ASLGRRIIELLSSNKLMTYFKENAIRHVNQNYTWMKATHLTANMYERIATQSPLRADEEE
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCCC
DSLSYIDDSFGSLIETIEKSRRKIRLAILDSAQAVYRSLARGGKVLVCGNGGSAAEAQHF
CHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
AAELMGRFEASGRRGLPAMALTADTAFVTAWSNDYTFDDVFARQVEAHGQPGDVLVVISS
HHHHHHHHHCCCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECC
SGQSVNLVKALRTARRHEMFCIGLLGKEGGPASELTDINIIVPSNETSRIQEVQLLVLHV
CCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
LSHLIEQQIVVDDLNTVQITEEWSIKHFQVQEMAKNVNKRKIKHESTKCD
HHHHHHHHHHHCCCCEEEEECCCCCCCEEHHHHHHCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA