Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 82702842

GI number: 82702842

Start: 1960546

End: 1961613

Strand: Direct

Name: namA [H]

Synonym: Nmul_A1718

Alternate gene names: 82702842

Gene position: 1960546-1961613 (Clockwise)

Preceding gene: 82702841

Following gene: 82702845

Centisome position: 61.57

GC content: 56.37

Gene sequence:

>1068_bases
ATGTCCCCGCTTACCCTTCGCGGCGTTACTTTCCGCAACCGCATCGCAATGTCTCCCATGTGCATGTATTCCGCCGAGGA
TGGTTTTGCCAACGACTTCCATCTCGTCCACCTGGGTAGCCGGGCAATCGGCGGCTTAGGGCTTGTGGTGGTCGAAGCCA
CTGCAGTCACGGCTGAGGGCCGTATTTCACCGGGAGACATGGGGATCTGGAAAGATGAACATATCGAGCCGTTGGCTCGC
ATTGCGCGGTTTGTGGAGATGCAGGGCGCGATTCCAGGCATCCAACTCGCACACGCCGGACGTAAAGCCAGTTGCGATGC
TCCCTGGAAAGGCGGCGGCAGCCTGAAAACGCCGGCAGAAGGAGGCTGGTCAGTGATTGGGCCCAGTCCCCTGCCGTTTT
ACGCTGATGATCCCGTCCCAACACCCATGTCGGAAACTGATATCGAGGAATGTATCGAGGCATGGGAAGCAGCCGCTCGA
CGTGCGCTGAACGCCGGCTTCAAAATGATAGAACTTCACGCGGCCCATGGTTACCTCATGCACGAATTTCTATCGCCGTT
AAGCAACCATCGTACTGATAGTTATGGCGGCAGCCTCGCAAATCGTACGCGGCTTTTGCTAAGGGTTGCCAAGGACCTTC
GCGATATTATCCCGTCCGAACTGCCTTTCTTCGTGCGAATCTCGGCAACCGACTGGGTCGAGGGAGGCTGGGATATGGAA
CAATCGATTATTCTCTGCAGAGAGCTGAAGCTGCTCGGGGTGGATCTGATCGATGTCTCCTCCGGCGGCGTGATACCGGA
TGCAAGAATTCCTGTTGCCAAAGGCTATCAGGTTCAATTTGCCCAACGCATCCGCGATGAAGCGCAAATCCGCACAGGCG
GAGTGGGACTCATCACCGACACGCAATACGCCGATGAGATCATCACCGGCGGTCAGGCAGATCTCGTTTTTATAGGCCGA
GAGTTACTGCGGGAGCCTTACTGGGCCCTCAAGGCGCAACATGCGTTAGCGATAGAACCAGAATGGCCGATCCAGTATGG
CTATGCTGTCAAGCGCCGTGCAAAATAG

Upstream 100 bases:

>100_bases
CGGCCCTCTGGGCAAGATCGGTGACCACCAGCTAAGCAGTGCCGCCATCCAGACACAATGTCAGAGCGAGCATGACCGGG
AAATCCCGGAAGTGGATCTC

Downstream 100 bases:

>100_bases
CCATGGCAGTTTAATTGCAATCCTGCTGCCGTGGGATAAAGAGAAGGAGTCGCCGGTATGCGCTGAATTGAGCATTCGGC
CTCAGCGTTCCGTTATCCCT

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSPLTLRGVTFRNRIAMSPMCMYSAEDGFANDFHLVHLGSRAIGGLGLVVVEATAVTAEGRISPGDMGIWKDEHIEPLAR
IARFVEMQGAIPGIQLAHAGRKASCDAPWKGGGSLKTPAEGGWSVIGPSPLPFYADDPVPTPMSETDIEECIEAWEAAAR
RALNAGFKMIELHAAHGYLMHEFLSPLSNHRTDSYGGSLANRTRLLLRVAKDLRDIIPSELPFFVRISATDWVEGGWDME
QSIILCRELKLLGVDLIDVSSGGVIPDARIPVAKGYQVQFAQRIRDEAQIRTGGVGLITDTQYADEIITGGQADLVFIGR
ELLREPYWALKAQHALAIEPEWPIQYGYAVKRRAK

Sequences:

>Translated_355_residues
MSPLTLRGVTFRNRIAMSPMCMYSAEDGFANDFHLVHLGSRAIGGLGLVVVEATAVTAEGRISPGDMGIWKDEHIEPLAR
IARFVEMQGAIPGIQLAHAGRKASCDAPWKGGGSLKTPAEGGWSVIGPSPLPFYADDPVPTPMSETDIEECIEAWEAAAR
RALNAGFKMIELHAAHGYLMHEFLSPLSNHRTDSYGGSLANRTRLLLRVAKDLRDIIPSELPFFVRISATDWVEGGWDME
QSIILCRELKLLGVDLIDVSSGGVIPDARIPVAKGYQVQFAQRIRDEAQIRTGGVGLITDTQYADEIITGGQADLVFIGR
ELLREPYWALKAQHALAIEPEWPIQYGYAVKRRAK
>Mature_354_residues
SPLTLRGVTFRNRIAMSPMCMYSAEDGFANDFHLVHLGSRAIGGLGLVVVEATAVTAEGRISPGDMGIWKDEHIEPLARI
ARFVEMQGAIPGIQLAHAGRKASCDAPWKGGGSLKTPAEGGWSVIGPSPLPFYADDPVPTPMSETDIEECIEAWEAAARR
ALNAGFKMIELHAAHGYLMHEFLSPLSNHRTDSYGGSLANRTRLLLRVAKDLRDIIPSELPFFVRISATDWVEGGWDMEQ
SIILCRELKLLGVDLIDVSSGGVIPDARIPVAKGYQVQFAQRIRDEAQIRTGGVGLITDTQYADEIITGGQADLVFIGRE
LLREPYWALKAQHALAIEPEWPIQYGYAVKRRAK

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=362, Percent_Identity=27.9005524861878, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789463, Length=342, Percent_Identity=25.4385964912281, Blast_Score=105, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17565138, Length=323, Percent_Identity=26.625386996904, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=229, Percent_Identity=28.82096069869, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI72001454, Length=257, Percent_Identity=28.4046692607004, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=229, Percent_Identity=28.82096069869, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=229, Percent_Identity=26.6375545851528, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17540738, Length=300, Percent_Identity=25.6666666666667, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=322, Percent_Identity=26.7080745341615, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321973, Length=189, Percent_Identity=26.984126984127, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=225, Percent_Identity=26.2222222222222, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 38900; Mature: 38769

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLTLRGVTFRNRIAMSPMCMYSAEDGFANDFHLVHLGSRAIGGLGLVVVEATAVTAEG
CCCCEEECCCHHHHHCCCCEEEEECCCCCCCCEEEEEECCHHHCCEEEEEEEEEEEEECC
RISPGDMGIWKDEHIEPLARIARFVEMQGAIPGIQLAHAGRKASCDAPWKGGGSLKTPAE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
GGWSVIGPSPLPFYADDPVPTPMSETDIEECIEAWEAAARRALNAGFKMIELHAAHGYLM
CCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHH
HEFLSPLSNHRTDSYGGSLANRTRLLLRVAKDLRDIIPSELPFFVRISATDWVEGGWDME
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHH
QSIILCRELKLLGVDLIDVSSGGVIPDARIPVAKGYQVQFAQRIRDEAQIRTGGVGLITD
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCEEEEEC
TQYADEIITGGQADLVFIGRELLREPYWALKAQHALAIEPEWPIQYGYAVKRRAK
CHHHHHHHCCCCCHHHHCCHHHHHCCHHHHCCCCEEEECCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
SPLTLRGVTFRNRIAMSPMCMYSAEDGFANDFHLVHLGSRAIGGLGLVVVEATAVTAEG
CCCEEECCCHHHHHCCCCEEEEECCCCCCCCEEEEEECCHHHCCEEEEEEEEEEEEECC
RISPGDMGIWKDEHIEPLARIARFVEMQGAIPGIQLAHAGRKASCDAPWKGGGSLKTPAE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
GGWSVIGPSPLPFYADDPVPTPMSETDIEECIEAWEAAARRALNAGFKMIELHAAHGYLM
CCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHH
HEFLSPLSNHRTDSYGGSLANRTRLLLRVAKDLRDIIPSELPFFVRISATDWVEGGWDME
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHH
QSIILCRELKLLGVDLIDVSSGGVIPDARIPVAKGYQVQFAQRIRDEAQIRTGGVGLITD
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCEEEEEC
TQYADEIITGGQADLVFIGRELLREPYWALKAQHALAIEPEWPIQYGYAVKRRAK
CHHHHHHHCCCCCHHHHCCHHHHHCCHHHHCCCCEEEECCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA