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The map label for this gene is insF1 [H]

Identifier: 82702561

GI number: 82702561

Start: 1644205

End: 1645047

Strand: Direct

Name: insF1 [H]

Synonym: Nmul_A1432

Alternate gene names: 82702561

Gene position: 1644205-1645047 (Clockwise)

Preceding gene: 82702560

Following gene: 82702563

Centisome position: 51.64

GC content: 55.75

Gene sequence:

>843_bases
ATGAGATATCGCATGATCGAACGCTGCCGCGATGCCTTCCCCATTCGCCTGATGTGTCGTTGTCTGCATGTATCAACCAG
CGGCTACTATGATTGGCGAGATCGCCCCTTGAGTCAGAGAGCGCATGATGACCGGCGTTTGCTGGAGCGCATCAGGAAGA
TTCATGATGGCAGCGATGGGGTGATGGGCAGTCCTCGAGTCTGGAAGGAGTTGCGTTATGAAGGCGAGGCGTGTGGGTTG
AACCGCATAGCACGGCTGATGCGCCAGCAGAGGTTGTATGGCATCCCGCAGCGTAAACGCTGGCACAAGAAGGTCTGTGG
CCTTCGACCGGAGAATGTGCACAATCACTTGCAGCGGGACTTTACAGCAAGTGAGCCCAACAGCCGGTGGGTGACGGACA
TAACCTATGTGCGCACTCAGGAAAGCTGGCTTTATCTGTGCGTGGTCGTGGACCTGTACTCGGGCATCGTGGTCGGCTGG
TCAATGAGCCACTGCCAGGATCCGCAACTGGTGCTGCAGGCCGTACTCATGGCGCTTTGGCAGCGTGAGGCAAAAACTCC
CGTCATCCTGCACTCAGATCGCGGCTGTCAGTTTACCAGTGACGAGTATCAACGCTTCCTGCAAGGACACAATCTGATTT
GCAGCATGAGCGCTGTCGGTAGTTGTGCCGACAACGCGCTAGCAGAGAGCTTCTTTGGCTTGCTCAAGCGGGAGCGAGTA
TATCGTCGCCAGTATCGAACCCGGGCTGAGGCGCGCACAGATATCTTCGACTATATCGAGCGATTCCATAATCCGCGAAA
ACGGCGACAGCTGGAAATGCGTCAGAAGCAGGATTTAGCTTAA

Upstream 100 bases:

>100_bases
GTGATGAGGAGATGGCTGCGCTCAAACGTGAGCTGATCCAAGTTAGGAAGGAGCGTGATTTTTTAAAAGAAGCGGCGGCG
TTATTCGCGAAAGCGTCGAA

Downstream 100 bases:

>100_bases
CCAAACCGTCCGGAGAAATGGGGTAAAACCCGGTAGGGTCAGCTAGTCCAGGTTTCCACTTTAGAACGGTACTGATTCCA
GAGTAGGGTGATCCTGCCCT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MRYRMIERCRDAFPIRLMCRCLHVSTSGYYDWRDRPLSQRAHDDRRLLERIRKIHDGSDGVMGSPRVWKELRYEGEACGL
NRIARLMRQQRLYGIPQRKRWHKKVCGLRPENVHNHLQRDFTASEPNSRWVTDITYVRTQESWLYLCVVVDLYSGIVVGW
SMSHCQDPQLVLQAVLMALWQREAKTPVILHSDRGCQFTSDEYQRFLQGHNLICSMSAVGSCADNALAESFFGLLKRERV
YRRQYRTRAEARTDIFDYIERFHNPRKRRQLEMRQKQDLA

Sequences:

>Translated_280_residues
MRYRMIERCRDAFPIRLMCRCLHVSTSGYYDWRDRPLSQRAHDDRRLLERIRKIHDGSDGVMGSPRVWKELRYEGEACGL
NRIARLMRQQRLYGIPQRKRWHKKVCGLRPENVHNHLQRDFTASEPNSRWVTDITYVRTQESWLYLCVVVDLYSGIVVGW
SMSHCQDPQLVLQAVLMALWQREAKTPVILHSDRGCQFTSDEYQRFLQGHNLICSMSAVGSCADNALAESFFGLLKRERV
YRRQYRTRAEARTDIFDYIERFHNPRKRRQLEMRQKQDLA
>Mature_280_residues
MRYRMIERCRDAFPIRLMCRCLHVSTSGYYDWRDRPLSQRAHDDRRLLERIRKIHDGSDGVMGSPRVWKELRYEGEACGL
NRIARLMRQQRLYGIPQRKRWHKKVCGLRPENVHNHLQRDFTASEPNSRWVTDITYVRTQESWLYLCVVVDLYSGIVVGW
SMSHCQDPQLVLQAVLMALWQREAKTPVILHSDRGCQFTSDEYQRFLQGHNLICSMSAVGSCADNALAESFFGLLKRERV
YRRQYRTRAEARTDIFDYIERFHNPRKRRQLEMRQKQDLA

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=243, Percent_Identity=34.156378600823, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1788405, Length=270, Percent_Identity=41.1111111111111, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1787263, Length=270, Percent_Identity=41.1111111111111, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1786753, Length=270, Percent_Identity=41.1111111111111, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1786570, Length=270, Percent_Identity=41.1111111111111, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1786490, Length=270, Percent_Identity=41.1111111111111, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1789981, Length=266, Percent_Identity=30.8270676691729, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33427; Mature: 33427

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYRMIERCRDAFPIRLMCRCLHVSTSGYYDWRDRPLSQRAHDDRRLLERIRKIHDGSDG
CCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCC
VMGSPRVWKELRYEGEACGLNRIARLMRQQRLYGIPQRKRWHKKVCGLRPENVHNHLQRD
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHC
FTASEPNSRWVTDITYVRTQESWLYLCVVVDLYSGIVVGWSMSHCQDPQLVLQAVLMALW
CCCCCCCCCEEEHHHEEEECCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHH
QREAKTPVILHSDRGCQFTSDEYQRFLQGHNLICSMSAVGSCADNALAESFFGLLKRERV
HHHCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
YRRQYRTRAEARTDIFDYIERFHNPRKRRQLEMRQKQDLA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRYRMIERCRDAFPIRLMCRCLHVSTSGYYDWRDRPLSQRAHDDRRLLERIRKIHDGSDG
CCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCC
VMGSPRVWKELRYEGEACGLNRIARLMRQQRLYGIPQRKRWHKKVCGLRPENVHNHLQRD
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHC
FTASEPNSRWVTDITYVRTQESWLYLCVVVDLYSGIVVGWSMSHCQDPQLVLQAVLMALW
CCCCCCCCCEEEHHHEEEECCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHHHHHH
QREAKTPVILHSDRGCQFTSDEYQRFLQGHNLICSMSAVGSCADNALAESFFGLLKRERV
HHHCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
YRRQYRTRAEARTDIFDYIERFHNPRKRRQLEMRQKQDLA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]