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The map label for this gene is silB [H]

Identifier: 82702536

GI number: 82702536

Start: 1614147

End: 1615769

Strand: Reverse

Name: silB [H]

Synonym: Nmul_A1407

Alternate gene names: 82702536

Gene position: 1615769-1614147 (Counterclockwise)

Preceding gene: 82702537

Following gene: 82702535

Centisome position: 50.74

GC content: 56.99

Gene sequence:

>1623_bases
GTGAAGCTTGGTGTCAAATTAACAGCTTTTGTTGCCCTGGCTGCAATCTTGTTTGTCGCCGGCTATTGGTGGGGCGCAAT
CCGGCCTTCGACTTCTGCCGCCAAGGCCTCGAGTGTGGTTTCAGTCGGCGGTAAGCCTGAAAGGAGGATTCTCTATTATC
GCAACCCCATGGGGCTGCCGGACACTTCGCCGATACCTAAAAAAGATCCCATGGGCATGGACTACATACCTGTTTACGAG
GACGAGGAATCCACTTCCGCCGATGCGGCAGTCAAGATCGGCGTCGAGAGGATACAAAAACTGGGAGTAAGAACCGAGCG
GGTCGGCATGCGCGAACTCAGCCGCACCGTAAGGGCGGTAGCGACAGTGCAGGCGGATGAACGACGGCTCTACGTCGTGG
CCCCCAGGTTCGAGGGATGGATCGAGCGGCTCCACGTCAACACGACGGGACAGATGGTCAGAAAGGGTGATCCATTGATG
GACGTGTATAGTCCCGACCTGATCACAGCCCAGCATGAATATCTTATCGCCCGGAGAGGAACAAAGGACGTGGAGGATGG
CGGCCTTGAGGTTCGGGCGGGGATGGAACGACTAGCTGAGAGTGCCTTGCAGAGACTGCGCAATTGGGACATATCCGCGG
CCGATCTGAAGACACTCCAGCAGGAAGGCAAGTTTACACATTCCGTCATATTTCGTTCTCCGGCAAGCGGCGTGGTTTTG
GAGAAACGGGCGATTCAGGGACAGCGCTTCATGGCGGGAGAGATTTTGTATCAGATTGCGGATCTCTCCAGAGTATGGGT
GCTCGCAGACGTGTTTGAGCAGGATCTTGCCACGATACAACCGGGGCAGGCTGCCGCCATTCGGGTTGAGGCCTATCCGG
ACAAGGTGTTCCCAGGCGAGGTGACGTTCATATACCCCACGGTCAATCCGGAAACCCGCACAGCCAAGGTTCGCATGGAG
CTGCCCAATCCACAGGAGTTGCTGAAACCGGCGATGTACGCGAAAGTGGAGTTTGGTTCAATCCAACGTAAGGACAGAGT
GCTCGCCGTCCCCGAATCGGCCGTACTCGATGCCGGTACCAGGCAGTCTGTGCTGGTGGATCTCGGCGAAGGCCGCTTTG
AACCGAGACTCGTGAAGCTGGGCAAGCACGCGGACGACTATGTGGAAGTTCTGGGGGGACTGAAGACTGGGGAAATGATT
GTGGTGAAAGCCAATTTTCTCATAGATGCCGAAAGCAACCTCAAGGCTGCACTGAGCAGTTTTACCCGCAGCAGCCAAGC
CTCGATGCCTGGTGAAGAGAGGGAGGGAGGCCGGACCGCCTCTGGCTCATCCGGAACTGTACCTTCATCCCCGTCCCCAT
CTTCATCGAGCCATCGCGGGGAAGGCATCATCGAAGCGATCGATGTGGCCAATACAACCCTGACTCTTGCCCACCGCCCG
ATCGCAAGCCTCGCCTGGCCGGAGATGTTGATGGACTTCAAGGTTCTGGACCCAGCGTTACTACGGATGTTGAAACCCGG
CCAGAAGGTTGCTTTCGAGATAACGGAAGCATCGCCGGGCGAATACGTTATTGTGCGTATACAGCCCCAGGCCAGCGCTG
CCGATCACGGAAAGAAGCCCTGA

Upstream 100 bases:

>100_bases
CAAGTTACAACAAGGCGCTTGCGGAGATCGATCTGCTCACTGGTAAATCGCCAGACAACTTATTACCTATTCCCCGGGAG
CTGATGTCAAAGGAGCACCT

Downstream 100 bases:

>100_bases
GATGGCCGGCAATATCATCGAATGGTCGGTACGGCACCTCTTCCTGGTGCTGGTCGGGACATTCTTCGTAATAGTCTGGG
GCTTATATTCAGTATGGAAG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MKLGVKLTAFVALAAILFVAGYWWGAIRPSTSAAKASSVVSVGGKPERRILYYRNPMGLPDTSPIPKKDPMGMDYIPVYE
DEESTSADAAVKIGVERIQKLGVRTERVGMRELSRTVRAVATVQADERRLYVVAPRFEGWIERLHVNTTGQMVRKGDPLM
DVYSPDLITAQHEYLIARRGTKDVEDGGLEVRAGMERLAESALQRLRNWDISAADLKTLQQEGKFTHSVIFRSPASGVVL
EKRAIQGQRFMAGEILYQIADLSRVWVLADVFEQDLATIQPGQAAAIRVEAYPDKVFPGEVTFIYPTVNPETRTAKVRME
LPNPQELLKPAMYAKVEFGSIQRKDRVLAVPESAVLDAGTRQSVLVDLGEGRFEPRLVKLGKHADDYVEVLGGLKTGEMI
VVKANFLIDAESNLKAALSSFTRSSQASMPGEEREGGRTASGSSGTVPSSPSPSSSSHRGEGIIEAIDVANTTLTLAHRP
IASLAWPEMLMDFKVLDPALLRMLKPGQKVAFEITEASPGEYVIVRIQPQASAADHGKKP

Sequences:

>Translated_540_residues
MKLGVKLTAFVALAAILFVAGYWWGAIRPSTSAAKASSVVSVGGKPERRILYYRNPMGLPDTSPIPKKDPMGMDYIPVYE
DEESTSADAAVKIGVERIQKLGVRTERVGMRELSRTVRAVATVQADERRLYVVAPRFEGWIERLHVNTTGQMVRKGDPLM
DVYSPDLITAQHEYLIARRGTKDVEDGGLEVRAGMERLAESALQRLRNWDISAADLKTLQQEGKFTHSVIFRSPASGVVL
EKRAIQGQRFMAGEILYQIADLSRVWVLADVFEQDLATIQPGQAAAIRVEAYPDKVFPGEVTFIYPTVNPETRTAKVRME
LPNPQELLKPAMYAKVEFGSIQRKDRVLAVPESAVLDAGTRQSVLVDLGEGRFEPRLVKLGKHADDYVEVLGGLKTGEMI
VVKANFLIDAESNLKAALSSFTRSSQASMPGEEREGGRTASGSSGTVPSSPSPSSSSHRGEGIIEAIDVANTTLTLAHRP
IASLAWPEMLMDFKVLDPALLRMLKPGQKVAFEITEASPGEYVIVRIQPQASAADHGKKP
>Mature_540_residues
MKLGVKLTAFVALAAILFVAGYWWGAIRPSTSAAKASSVVSVGGKPERRILYYRNPMGLPDTSPIPKKDPMGMDYIPVYE
DEESTSADAAVKIGVERIQKLGVRTERVGMRELSRTVRAVATVQADERRLYVVAPRFEGWIERLHVNTTGQMVRKGDPLM
DVYSPDLITAQHEYLIARRGTKDVEDGGLEVRAGMERLAESALQRLRNWDISAADLKTLQQEGKFTHSVIFRSPASGVVL
EKRAIQGQRFMAGEILYQIADLSRVWVLADVFEQDLATIQPGQAAAIRVEAYPDKVFPGEVTFIYPTVNPETRTAKVRME
LPNPQELLKPAMYAKVEFGSIQRKDRVLAVPESAVLDAGTRQSVLVDLGEGRFEPRLVKLGKHADDYVEVLGGLKTGEMI
VVKANFLIDAESNLKAALSSFTRSSQASMPGEEREGGRTASGSSGTVPSSPSPSSSSHRGEGIIEAIDVANTTLTLAHRP
IASLAWPEMLMDFKVLDPALLRMLKPGQKVAFEITEASPGEYVIVRIQPQASAADHGKKP

Specific function: Component of the sil cation efflux system that confers resistance to silver. May be part of a three-component cation/proton antiporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=429, Percent_Identity=30.3030303030303, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI87081796, Length=326, Percent_Identity=26.9938650306748, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 59137; Mature: 59137

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGVKLTAFVALAAILFVAGYWWGAIRPSTSAAKASSVVSVGGKPERRILYYRNPMGLP
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCEEECCCCCCCEEEEEECCCCCC
DTSPIPKKDPMGMDYIPVYEDEESTSADAAVKIGVERIQKLGVRTERVGMRELSRTVRAV
CCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ATVQADERRLYVVAPRFEGWIERLHVNTTGQMVRKGDPLMDVYSPDLITAQHEYLIARRG
HHEEECCCEEEEECCCHHHHHHHEECCCHHHHHHCCCCCEECCCCCEEECCHHEEEEECC
TKDVEDGGLEVRAGMERLAESALQRLRNWDISAADLKTLQQEGKFTHSVIFRSPASGVVL
CCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCCEEE
EKRAIQGQRFMAGEILYQIADLSRVWVLADVFEQDLATIQPGQAAAIRVEAYPDKVFPGE
EHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
VTFIYPTVNPETRTAKVRMELPNPQELLKPAMYAKVEFGSIQRKDRVLAVPESAVLDAGT
EEEEEECCCCCCCEEEEEEECCCHHHHHCHHHHEEEECCCCCCCCCEEECCCHHHHCCCC
RQSVLVDLGEGRFEPRLVKLGKHADDYVEVLGGLKTGEMIVVKANFLIDAESNLKAALSS
CCEEEEECCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHH
FTRSSQASMPGEEREGGRTASGSSGTVPSSPSPSSSSHRGEGIIEAIDVANTTLTLAHRP
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCC
IASLAWPEMLMDFKVLDPALLRMLKPGQKVAFEITEASPGEYVIVRIQPQASAADHGKKP
HHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKLGVKLTAFVALAAILFVAGYWWGAIRPSTSAAKASSVVSVGGKPERRILYYRNPMGLP
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCEEECCCCCCCEEEEEECCCCCC
DTSPIPKKDPMGMDYIPVYEDEESTSADAAVKIGVERIQKLGVRTERVGMRELSRTVRAV
CCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ATVQADERRLYVVAPRFEGWIERLHVNTTGQMVRKGDPLMDVYSPDLITAQHEYLIARRG
HHEEECCCEEEEECCCHHHHHHHEECCCHHHHHHCCCCCEECCCCCEEECCHHEEEEECC
TKDVEDGGLEVRAGMERLAESALQRLRNWDISAADLKTLQQEGKFTHSVIFRSPASGVVL
CCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCCEEE
EKRAIQGQRFMAGEILYQIADLSRVWVLADVFEQDLATIQPGQAAAIRVEAYPDKVFPGE
EHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
VTFIYPTVNPETRTAKVRMELPNPQELLKPAMYAKVEFGSIQRKDRVLAVPESAVLDAGT
EEEEEECCCCCCCEEEEEEECCCHHHHHCHHHHEEEECCCCCCCCCEEECCCHHHHCCCC
RQSVLVDLGEGRFEPRLVKLGKHADDYVEVLGGLKTGEMIVVKANFLIDAESNLKAALSS
CCEEEEECCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHH
FTRSSQASMPGEEREGGRTASGSSGTVPSSPSPSSSSHRGEGIIEAIDVANTTLTLAHRP
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCC
IASLAWPEMLMDFKVLDPALLRMLKPGQKVAFEITEASPGEYVIVRIQPQASAADHGKKP
HHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9930866 [H]