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The map label for this gene is ycfH [H]

Identifier: 82702510

GI number: 82702510

Start: 1573661

End: 1574425

Strand: Reverse

Name: ycfH [H]

Synonym: Nmul_A1381

Alternate gene names: 82702510

Gene position: 1574425-1573661 (Counterclockwise)

Preceding gene: 82702511

Following gene: 82702509

Centisome position: 49.44

GC content: 53.33

Gene sequence:

>765_bases
ATGTTTGTCGATTCCCATTGTCATCTTGATTTTCCCGATCTCGCGAGCAGGCTGGATGAATTGCTGGCACGAATGCGGGA
AAATGACGTCAGTCATGCACTCTGCGTGAGTGTCAATCTCCAGGATTTTCCCCGAGTCCGCGCTCTTGCCGAGAACCATC
CCAATTTATATGCCTCGGTTGGCGTCCACCCTGATTATGAAAATCTCGCCGAACCGCAGGCGGCACAATTGGCGTCTTTG
GCTGATCATCCAAAGGTGGTGGCGATAGGTGAGACCGGCCTGGATTATTTCCGCCTCAAGGGCGATCTCGAATGGCAGCG
GGAGCGTTTCCGTGAGCATATCCGCGCTGCCCGCCAATGCTCGAAACCGCTCATCATCCACACGCGTGAAGCCGCTGCCG
ATACACTGAGGATTATGGCGGAGGAGGGTGCAGACAAGGTGGGGGGAGTCATGCATTGCTTTACGGAAAGCTGGGAAGTA
GCGCGGCAGGCGATGGAAATGAATTTCTATATATCGTTTTCAGGCATTGTCACATTCAAAAATGCCGTTGCGTTGAAGGA
TGTGGCCAGAAGAATCAGTCTGGACAGGATATTGATAGAAACGGACTCACCCTATCTTGCTCCCGTGCCGCATCGGGGCA
AGACAAACGAACCCGCGTTTGTGAGAAACGTCGCAGAAGAAATAGCAGCGCTGCGCGGCGTCCCTATCGAGGAAATCGGC
AGGATCACGACCGATAACTTTTTCAACTTGTTCAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCGGTAATCAACTGACGCCCATAAGCCAGTATCCCTGGATCAGGGGAATAATTGTTGTTGTCGTGATGTCTTCCTTTCTC
CTTTTTGACCGGGTTCCACC

Downstream 100 bases:

>100_bases
ATTATGAGGTCATCCAGAAAATTATTTATGGCTGGTCTGGTGCTTGCTGCCAGTCTCTCTCAGCAGCCTTATGCAATGGG
TGGGGTTTATGAAGATTTGC

Product: TatD-related deoxyribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MFVDSHCHLDFPDLASRLDELLARMRENDVSHALCVSVNLQDFPRVRALAENHPNLYASVGVHPDYENLAEPQAAQLASL
ADHPKVVAIGETGLDYFRLKGDLEWQRERFREHIRAARQCSKPLIIHTREAAADTLRIMAEEGADKVGGVMHCFTESWEV
ARQAMEMNFYISFSGIVTFKNAVALKDVARRISLDRILIETDSPYLAPVPHRGKTNEPAFVRNVAEEIAALRGVPIEEIG
RITTDNFFNLFKAA

Sequences:

>Translated_254_residues
MFVDSHCHLDFPDLASRLDELLARMRENDVSHALCVSVNLQDFPRVRALAENHPNLYASVGVHPDYENLAEPQAAQLASL
ADHPKVVAIGETGLDYFRLKGDLEWQRERFREHIRAARQCSKPLIIHTREAAADTLRIMAEEGADKVGGVMHCFTESWEV
ARQAMEMNFYISFSGIVTFKNAVALKDVARRISLDRILIETDSPYLAPVPHRGKTNEPAFVRNVAEEIAALRGVPIEEIG
RITTDNFFNLFKAA
>Mature_254_residues
MFVDSHCHLDFPDLASRLDELLARMRENDVSHALCVSVNLQDFPRVRALAENHPNLYASVGVHPDYENLAEPQAAQLASL
ADHPKVVAIGETGLDYFRLKGDLEWQRERFREHIRAARQCSKPLIIHTREAAADTLRIMAEEGADKVGGVMHCFTESWEV
ARQAMEMNFYISFSGIVTFKNAVALKDVARRISLDRILIETDSPYLAPVPHRGKTNEPAFVRNVAEEIAALRGVPIEEIG
RITTDNFFNLFKAA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI226061853, Length=271, Percent_Identity=29.1512915129151, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=28.9473684210526, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=28.9473684210526, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI225903424, Length=256, Percent_Identity=30.46875, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=28.2352941176471, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI14042943, Length=264, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI225903439, Length=243, Percent_Identity=27.9835390946502, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=28.0701754385965, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1787342, Length=255, Percent_Identity=49.8039215686275, Blast_Score=244, Evalue=5e-66,
Organism=Escherichia coli, GI87082439, Length=253, Percent_Identity=31.6205533596838, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI48994985, Length=261, Percent_Identity=30.2681992337165, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17559024, Length=279, Percent_Identity=29.0322580645161, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17565396, Length=303, Percent_Identity=28.0528052805281, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=294, Percent_Identity=29.2517006802721, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71980746, Length=262, Percent_Identity=25.9541984732824, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586117, Length=270, Percent_Identity=30, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI221330018, Length=270, Percent_Identity=30, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=26.5017667844523, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28595; Mature: 28595

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDSHCHLDFPDLASRLDELLARMRENDVSHALCVSVNLQDFPRVRALAENHPNLYASV
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEE
GVHPDYENLAEPQAAQLASLADHPKVVAIGETGLDYFRLKGDLEWQRERFREHIRAARQC
CCCCCHHHHCCCHHHHHHHHCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHC
SKPLIIHTREAAADTLRIMAEEGADKVGGVMHCFTESWEVARQAMEMNFYISFSGIVTFK
CCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEHH
NAVALKDVARRISLDRILIETDSPYLAPVPHRGKTNEPAFVRNVAEEIAALRGVPIEEIG
HHHHHHHHHHHHHHCEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHC
RITTDNFFNLFKAA
CCCHHHHHHHHHCC
>Mature Secondary Structure
MFVDSHCHLDFPDLASRLDELLARMRENDVSHALCVSVNLQDFPRVRALAENHPNLYASV
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEE
GVHPDYENLAEPQAAQLASLADHPKVVAIGETGLDYFRLKGDLEWQRERFREHIRAARQC
CCCCCHHHHCCCHHHHHHHHCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHC
SKPLIIHTREAAADTLRIMAEEGADKVGGVMHCFTESWEVARQAMEMNFYISFSGIVTFK
CCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEHH
NAVALKDVARRISLDRILIETDSPYLAPVPHRGKTNEPAFVRNVAEEIAALRGVPIEEIG
HHHHHHHHHHHHHHCEEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHC
RITTDNFFNLFKAA
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]