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The map label for this gene is hchA [H]

Identifier: 82702499

GI number: 82702499

Start: 1556853

End: 1557542

Strand: Reverse

Name: hchA [H]

Synonym: Nmul_A1370

Alternate gene names: 82702499

Gene position: 1557542-1556853 (Counterclockwise)

Preceding gene: 82702501

Following gene: 82702498

Centisome position: 48.91

GC content: 55.65

Gene sequence:

>690_bases
ATGAAAATTCTCATCGTTCTGACATCCCATGATCAACTTGGCGACACTGGAAAGAAGACCGGCTTCTGGCTGGAAGAATT
CGTTGCTCCCTATTATGCATTCAAGGATGCGGGAGCGGAAATCACGCTGGCATCGCCGAAAGGCAATATGCCGCCGATCG
ACCCCAAAAGCGATCTCCCGGAAAATCAGACTCACCTGACGCGCCGCTTTCGGACAGACGGCGCCGCGCAGGCTGAGCTT
GCCCATACGAAAGAGCTGACCTATATCTCGGCAGCCGATTACGATGCGGTCTTTTATCCCGGAGGGCATGGGCCGATGTG
GGACATGCCGGACAACCGCATATCCATTTCACTGCTGGAGGAATTCATAGAAGCCGATAAACCGATTGCCGCAGTGTGTC
ATGCTCCCGCCGCTTTGGTCAATGTGCGTGGAAAAGACGGGGAGTATCTGGTCAAAGGGATGCGCGTGACCGGTTTTTCA
AATGCCGAGGAAGCAGCAGTCGGCTTGACCCCGGTTGTTCCGTTCCTGCTGGAAGACCGATTGAGGGAACGTGGCGCCAT
TTACAGCAAAGCGGACAACTGGACGCCCTATGTCAAGGTCGATGACAAGCTGATAACCGGCCAGAATCCCGCCTCTTCCC
GGCTGGCAGCGGAAGAACTGCTGCGGCTACTCCATGTCGTCGCCGCATAA

Upstream 100 bases:

>100_bases
GGCCGACTGTCGAGTTTGAAAGCGATGCCAATACCTGCTATAGGTTAACTGTTCCAATTTTCCGTTGGCGTTTCGATGTT
TTTCCACAAAGGAGATGAAC

Downstream 100 bases:

>100_bases
AGGCAGAATCCGCCGGACCTCCATCGGCAGGAGTCTATCGAGAGGAGAAGCAGGAGAAGCGTTCCCTGCCGACCAGGGAG
CAAGATAAACAGGAAAAGGA

Product: ThiJ/PfpI

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MKILIVLTSHDQLGDTGKKTGFWLEEFVAPYYAFKDAGAEITLASPKGNMPPIDPKSDLPENQTHLTRRFRTDGAAQAEL
AHTKELTYISAADYDAVFYPGGHGPMWDMPDNRISISLLEEFIEADKPIAAVCHAPAALVNVRGKDGEYLVKGMRVTGFS
NAEEAAVGLTPVVPFLLEDRLRERGAIYSKADNWTPYVKVDDKLITGQNPASSRLAAEELLRLLHVVAA

Sequences:

>Translated_229_residues
MKILIVLTSHDQLGDTGKKTGFWLEEFVAPYYAFKDAGAEITLASPKGNMPPIDPKSDLPENQTHLTRRFRTDGAAQAEL
AHTKELTYISAADYDAVFYPGGHGPMWDMPDNRISISLLEEFIEADKPIAAVCHAPAALVNVRGKDGEYLVKGMRVTGFS
NAEEAAVGLTPVVPFLLEDRLRERGAIYSKADNWTPYVKVDDKLITGQNPASSRLAAEELLRLLHVVAA
>Mature_229_residues
MKILIVLTSHDQLGDTGKKTGFWLEEFVAPYYAFKDAGAEITLASPKGNMPPIDPKSDLPENQTHLTRRFRTDGAAQAEL
AHTKELTYISAADYDAVFYPGGHGPMWDMPDNRISISLLEEFIEADKPIAAVCHAPAALVNVRGKDGEYLVKGMRVTGFS
NAEEAAVGLTPVVPFLLEDRLRERGAIYSKADNWTPYVKVDDKLITGQNPASSRLAAEELLRLLHVVAA

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Homo sapiens, GI310129235, Length=190, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI239749942, Length=190, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI32699045, Length=190, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI310129239, Length=167, Percent_Identity=28.1437125748503, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI310129233, Length=167, Percent_Identity=28.1437125748503, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788278, Length=236, Percent_Identity=27.1186440677966, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320742, Length=226, Percent_Identity=29.646017699115, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324967, Length=225, Percent_Identity=28, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324975, Length=225, Percent_Identity=28, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323984, Length=225, Percent_Identity=27.1111111111111, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 25124; Mature: 25124

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIVLTSHDQLGDTGKKTGFWLEEFVAPYYAFKDAGAEITLASPKGNMPPIDPKSDLP
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCC
ENQTHLTRRFRTDGAAQAELAHTKELTYISAADYDAVFYPGGHGPMWDMPDNRISISLLE
CCHHHHHHHHCCCCCCHHHHHHHHHEEEEEECCCCEEEECCCCCCCCCCCCCCEEHHHHH
EFIEADKPIAAVCHAPAALVNVRGKDGEYLVKGMRVTGFSNAEEAAVGLTPVVPFLLEDR
HHHHCCCCHHHHHCCCEEEEEECCCCCCEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHH
LRERGAIYSKADNWTPYVKVDDKLITGQNPASSRLAAEELLRLLHVVAA
HHHCCCEEECCCCCCCEEEECCEEECCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKILIVLTSHDQLGDTGKKTGFWLEEFVAPYYAFKDAGAEITLASPKGNMPPIDPKSDLP
CEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCC
ENQTHLTRRFRTDGAAQAELAHTKELTYISAADYDAVFYPGGHGPMWDMPDNRISISLLE
CCHHHHHHHHCCCCCCHHHHHHHHHEEEEEECCCCEEEECCCCCCCCCCCCCCEEHHHHH
EFIEADKPIAAVCHAPAALVNVRGKDGEYLVKGMRVTGFSNAEEAAVGLTPVVPFLLEDR
HHHHCCCCHHHHHCCCEEEEEECCCCCCEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHH
LRERGAIYSKADNWTPYVKVDDKLITGQNPASSRLAAEELLRLLHVVAA
HHHCCCEEECCCCCCCEEEECCEEECCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA