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The map label for this gene is 82702315

Identifier: 82702315

GI number: 82702315

Start: 1374441

End: 1375454

Strand: Direct

Name: 82702315

Synonym: Nmul_A1186

Alternate gene names: NA

Gene position: 1374441-1375454 (Clockwise)

Preceding gene: 82702314

Following gene: 82702316

Centisome position: 43.16

GC content: 53.85

Gene sequence:

>1014_bases
ATGAAAATATCAACAACAGTTGTCGCACTTGTCGTGTTGCTGTCTGGCGGAAGCGCCGGTGCTGCTTCCCCTTTCAGCAG
TCTTATCGTATTCGGAGACAGCCTGTCCGATGTGGGAGACAATCCTTCCGGCGTCAACAGTCTTTACAAAGAGCTCGGCG
GTAATTGCGATCCCTTGCATCCCTGCCTGCCATCACAACTTGGGCCGTCGTATGATGGTGGCCGCTTCTCCAACGGGCCC
GTCGCCTCGGAGTATCTGGCGAAAAACCTCTTTCCCGCCGGCGTAAATACGGCTAATTTTCAGGGCTATGCCGTCGCGGG
TGCGACGTCGGGTAACCACAACGTCGGTAATGATGCTGATCCAACAGGAATATTGAACTTGCCGGGCATGCAGCAGGAGG
TGAATCTCTACCTGAGTAATGCAGGCGGAGCAGCAGATCCAAACGCGTTGTACTTCGTATGGGGCGGAAGCAATGATTAT
CTTATCCATGATTCTCCCGTTCAGGCCGCCCGAAACATAGGAAGTTATGTGAATGTGCTTGCAGCGGCGGGAGCGAGGAA
TTTTCTTGTGCCAAACCTGCCTGATCTCGGTCTTACCCCATCCGCCAGGATGGATAACGAAGTGTCGCTGGCGCACGACT
ATTCCGTAGTGTTCAATACGGAATTGGCGAGTCAGCTCGGAAGTCTCGATGGCACTTTTCCAGGGTTAAACATACAGCGC
TTCGACACCTTCTCGTTATTGAACGATGTCGTCCAGAATCCGATGAACTATGGACTTACCGATGTGACCAATCCGTGTTT
CACCCTGCTGGGGGTTACATGCGACAATCCCGAGGTACGTCTCTTCTGGGATGATTTTCATCCCACCACCAACGCTCACG
CGATTCTCGGTGCGGCTTTCGCGGCTGCAGTGCCGGAACCAGCAACGATCTTTATGTTCATGCTTGGCCTGCTGGTGCTT
GCCTCCACAGCAGGCAGGAGACAAAAAACCATGCCGGCGCGGCGGCAGGTATAA

Upstream 100 bases:

>100_bases
TGATATTCGCCAGGAAAAGCATCCTGAAAACCATCCCGCTGTTTAGGCGACATTTGGTGCTCCCTTAAAAAAACGATCTC
TGAGCCAAGGAGGACTGACA

Downstream 100 bases:

>100_bases
GTGCAGATGTCGAAGTGATAGAGGTGAGGATATTGCCTGAAACGGTTTCCACGATATTTCCGTTCCCATGCTGGTGACAT
TCAAGACTTCTGCCCATGCT

Product: lipolytic protein

Products: NA

Alternate protein names: Glycerophospholipid-cholesterol acyltransferase; GCAT [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKISTTVVALVVLLSGGSAGAASPFSSLIVFGDSLSDVGDNPSGVNSLYKELGGNCDPLHPCLPSQLGPSYDGGRFSNGP
VASEYLAKNLFPAGVNTANFQGYAVAGATSGNHNVGNDADPTGILNLPGMQQEVNLYLSNAGGAADPNALYFVWGGSNDY
LIHDSPVQAARNIGSYVNVLAAAGARNFLVPNLPDLGLTPSARMDNEVSLAHDYSVVFNTELASQLGSLDGTFPGLNIQR
FDTFSLLNDVVQNPMNYGLTDVTNPCFTLLGVTCDNPEVRLFWDDFHPTTNAHAILGAAFAAAVPEPATIFMFMLGLLVL
ASTAGRRQKTMPARRQV

Sequences:

>Translated_337_residues
MKISTTVVALVVLLSGGSAGAASPFSSLIVFGDSLSDVGDNPSGVNSLYKELGGNCDPLHPCLPSQLGPSYDGGRFSNGP
VASEYLAKNLFPAGVNTANFQGYAVAGATSGNHNVGNDADPTGILNLPGMQQEVNLYLSNAGGAADPNALYFVWGGSNDY
LIHDSPVQAARNIGSYVNVLAAAGARNFLVPNLPDLGLTPSARMDNEVSLAHDYSVVFNTELASQLGSLDGTFPGLNIQR
FDTFSLLNDVVQNPMNYGLTDVTNPCFTLLGVTCDNPEVRLFWDDFHPTTNAHAILGAAFAAAVPEPATIFMFMLGLLVL
ASTAGRRQKTMPARRQV
>Mature_337_residues
MKISTTVVALVVLLSGGSAGAASPFSSLIVFGDSLSDVGDNPSGVNSLYKELGGNCDPLHPCLPSQLGPSYDGGRFSNGP
VASEYLAKNLFPAGVNTANFQGYAVAGATSGNHNVGNDADPTGILNLPGMQQEVNLYLSNAGGAADPNALYFVWGGSNDY
LIHDSPVQAARNIGSYVNVLAAAGARNFLVPNLPDLGLTPSARMDNEVSLAHDYSVVFNTELASQLGSLDGTFPGLNIQR
FDTFSLLNDVVQNPMNYGLTDVTNPCFTLLGVTCDNPEVRLFWDDFHPTTNAHAILGAAFAAAVPEPATIFMFMLGLLVL
ASTAGRRQKTMPARRQV

Specific function: Fatty acid transfer between phosphatidylcholine and cholesterol [H]

COG id: COG3240

COG function: function code IR; Phospholipase/lecithinase/hemolysin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: =2.3.1.43 [H]

Molecular weight: Translated: 35345; Mature: 35345

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTTVVALVVLLSGGSAGAASPFSSLIVFGDSLSDVGDNPSGVNSLYKELGGNCDPLH
CCCHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCHHHCCCCCHHHHHHHHHHCCCCCCCC
PCLPSQLGPSYDGGRFSNGPVASEYLAKNLFPAGVNTANFQGYAVAGATSGNHNVGNDAD
CCCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
PTGILNLPGMQQEVNLYLSNAGGAADPNALYFVWGGSNDYLIHDSPVQAARNIGSYVNVL
CCCEEECCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHH
AAAGARNFLVPNLPDLGLTPSARMDNEVSLAHDYSVVFNTELASQLGSLDGTFPGLNIQR
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECEEEEECHHHHHHHCCCCCCCCCCCEEH
FDTFSLLNDVVQNPMNYGLTDVTNPCFTLLGVTCDNPEVRLFWDDFHPTTNAHAILGAAF
HHHHHHHHHHHHCHHHCCCHHCCCHHHHHEEEECCCCCEEEEECCCCCCCCHHHHHHHHH
AAAVPEPATIFMFMLGLLVLASTAGRRQKTMPARRQV
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCC
>Mature Secondary Structure
MKISTTVVALVVLLSGGSAGAASPFSSLIVFGDSLSDVGDNPSGVNSLYKELGGNCDPLH
CCCHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCHHHCCCCCHHHHHHHHHHCCCCCCCC
PCLPSQLGPSYDGGRFSNGPVASEYLAKNLFPAGVNTANFQGYAVAGATSGNHNVGNDAD
CCCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
PTGILNLPGMQQEVNLYLSNAGGAADPNALYFVWGGSNDYLIHDSPVQAARNIGSYVNVL
CCCEEECCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHH
AAAGARNFLVPNLPDLGLTPSARMDNEVSLAHDYSVVFNTELASQLGSLDGTFPGLNIQR
HHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECEEEEECHHHHHHHCCCCCCCCCCCEEH
FDTFSLLNDVVQNPMNYGLTDVTNPCFTLLGVTCDNPEVRLFWDDFHPTTNAHAILGAAF
HHHHHHHHHHHHCHHHCCCHHCCCHHHHHEEEECCCCCEEEEECCCCCCCCHHHHHHHHH
AAAVPEPATIFMFMLGLLVLASTAGRRQKTMPARRQV
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2271578; 3280033; 1985976; 8294469 [H]