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The map label for this gene is argF [H]

Identifier: 82702171

GI number: 82702171

Start: 1205440

End: 1206429

Strand: Direct

Name: argF [H]

Synonym: Nmul_A1042

Alternate gene names: 82702171

Gene position: 1205440-1206429 (Clockwise)

Preceding gene: 82702170

Following gene: 82702172

Centisome position: 37.86

GC content: 55.15

Gene sequence:

>990_bases
TTGAAGTCAGCCGGCCCAAGTCTTCGCAATAGTCTTCGCAACGGACTCGCCCCTGACACCAAAAATATGCAGATCAAGCA
TTTCTTACAGTTCAACGATTTTTCCCGGGAGGAATTCGAGTATCTGTTCGAGCGCACGCGCTGGATCAAGCAGGAGTTCA
AGCAATACCGACGCTACTGGCCCCTGGAAGACCGTACTCTGGCCATGATCTTTGACAAGCATTCAACCCGCACCAGGCTT
TCGTTTGAGGCGGGCATGCACCAGTTGGGCGGGGCGGCGATCTATCTTTCCACTCGTGATACCCAGTTGGGGCGCGGCGA
GCCGGTCGAAGATGCGGCCCGGGTGATTTCGCGGATGGTGGATATCGTCATGATCCGTACCCATGAGCATGATATCGTCA
GGCGGTTTGCGGCGCATTCGCGTGTTCCGGTCATTAATGGACTGACCGATGAATATCACCCCTGCCAGATCATTGGGGAT
ATTTTTACGTTCATCGAGCACCATGGCAGCATTACCGGCAAGACGGTGGCGTGGATAGGGGACTCCAACAACGTTTGCAA
TACGTGGCTTCAGGCAGCGGAAGTATTCGATTTCAACGTCCATGTCTCCACTCCGCGAGGCTACGAAGTGGAGCCGGAAC
GGGCCGGTCTTTACGGGACAAGCCACTATGAGGAGTTTGCGGATCCACATGAGGCAGTAAAAGGTGCAGACCTCGTTACC
ACGGACGTCTGGACCAGCATGGGATTCGAGGCCGAAACCGAGGAGCGAAAAAGGGATTTTGCGGATTTTCGGGTGGATGC
GGAAATGATGTCGCACACCCGCAAGGATGCGTTGTTCATGCATTGCCTGCCTGCTCATCGCGGGGAGGAAGTGGCGGCGG
AAGTGATAGACGGACCGCAATCGGTGGTATGGGATGAAGCGGAGAACCGGCTGCATACGCAAAAGGCGCTGATTGAATAC
CTGTTGCTGGGAAGACTGGATAACGCCTGA

Upstream 100 bases:

>100_bases
ATTCAACGCAGCGAGGCTGAGCAGGTAGTCAACATTTTATCTCCCATTGTGAAGGAATTTCTGGCAGCTTGAGTTTTTTG
CGATCGCAAAAAGTGAACGG

Downstream 100 bases:

>100_bases
TAGAGCAGGATTTTCAATAGGAGTTATTCGGGAAGTCAAGCCGGCATTTTTATTAATGAGACAAGCATGGGAAAAGAAAC
AAGGTGAATGTCGCTCAGAT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKSAGPSLRNSLRNGLAPDTKNMQIKHFLQFNDFSREEFEYLFERTRWIKQEFKQYRRYWPLEDRTLAMIFDKHSTRTRL
SFEAGMHQLGGAAIYLSTRDTQLGRGEPVEDAARVISRMVDIVMIRTHEHDIVRRFAAHSRVPVINGLTDEYHPCQIIGD
IFTFIEHHGSITGKTVAWIGDSNNVCNTWLQAAEVFDFNVHVSTPRGYEVEPERAGLYGTSHYEEFADPHEAVKGADLVT
TDVWTSMGFEAETEERKRDFADFRVDAEMMSHTRKDALFMHCLPAHRGEEVAAEVIDGPQSVVWDEAENRLHTQKALIEY
LLLGRLDNA

Sequences:

>Translated_329_residues
MKSAGPSLRNSLRNGLAPDTKNMQIKHFLQFNDFSREEFEYLFERTRWIKQEFKQYRRYWPLEDRTLAMIFDKHSTRTRL
SFEAGMHQLGGAAIYLSTRDTQLGRGEPVEDAARVISRMVDIVMIRTHEHDIVRRFAAHSRVPVINGLTDEYHPCQIIGD
IFTFIEHHGSITGKTVAWIGDSNNVCNTWLQAAEVFDFNVHVSTPRGYEVEPERAGLYGTSHYEEFADPHEAVKGADLVT
TDVWTSMGFEAETEERKRDFADFRVDAEMMSHTRKDALFMHCLPAHRGEEVAAEVIDGPQSVVWDEAENRLHTQKALIEY
LLLGRLDNA
>Mature_329_residues
MKSAGPSLRNSLRNGLAPDTKNMQIKHFLQFNDFSREEFEYLFERTRWIKQEFKQYRRYWPLEDRTLAMIFDKHSTRTRL
SFEAGMHQLGGAAIYLSTRDTQLGRGEPVEDAARVISRMVDIVMIRTHEHDIVRRFAAHSRVPVINGLTDEYHPCQIIGD
IFTFIEHHGSITGKTVAWIGDSNNVCNTWLQAAEVFDFNVHVSTPRGYEVEPERAGLYGTSHYEEFADPHEAVKGADLVT
TDVWTSMGFEAETEERKRDFADFRVDAEMMSHTRKDALFMHCLPAHRGEEVAAEVIDGPQSVVWDEAENRLHTQKALIEY
LLLGRLDNA

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=314, Percent_Identity=37.8980891719745, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI18105007, Length=311, Percent_Identity=26.6881028938907, Blast_Score=119, Evalue=5e-27,
Organism=Escherichia coli, GI1786469, Length=327, Percent_Identity=35.1681957186544, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1790703, Length=327, Percent_Identity=34.2507645259939, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI2367364, Length=312, Percent_Identity=27.5641025641026, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI48994908, Length=269, Percent_Identity=26.0223048327138, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=288, Percent_Identity=26.7361111111111, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322373, Length=319, Percent_Identity=34.4827586206897, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6322331, Length=279, Percent_Identity=27.5985663082437, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24642586, Length=317, Percent_Identity=26.1829652996845, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37891; Mature: 37891

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAGPSLRNSLRNGLAPDTKNMQIKHFLQFNDFSREEFEYLFERTRWIKQEFKQYRRYW
CCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PLEDRTLAMIFDKHSTRTRLSFEAGMHQLGGAAIYLSTRDTQLGRGEPVEDAARVISRMV
CCCCCEEEEEEECCCCCCEEEHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHH
DIVMIRTHEHDIVRRFAAHSRVPVINGLTDEYHPCQIIGDIFTFIEHHGSITGKTVAWIG
HHHHEECCHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEC
DSNNVCNTWLQAAEVFDFNVHVSTPRGYEVEPERAGLYGTSHYEEFADPHEAVKGADLVT
CCCCHHHHHHHHHHHEEEEEEEECCCCCCCCHHHCCCCCCCHHHHHCCHHHHHCCCCCEE
TDVWTSMGFEAETEERKRDFADFRVDAEMMSHTRKDALFMHCLPAHRGEEVAAEVIDGPQ
HHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
SVVWDEAENRLHTQKALIEYLLLGRLDNA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSAGPSLRNSLRNGLAPDTKNMQIKHFLQFNDFSREEFEYLFERTRWIKQEFKQYRRYW
CCCCCHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
PLEDRTLAMIFDKHSTRTRLSFEAGMHQLGGAAIYLSTRDTQLGRGEPVEDAARVISRMV
CCCCCEEEEEEECCCCCCEEEHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHH
DIVMIRTHEHDIVRRFAAHSRVPVINGLTDEYHPCQIIGDIFTFIEHHGSITGKTVAWIG
HHHHEECCHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEC
DSNNVCNTWLQAAEVFDFNVHVSTPRGYEVEPERAGLYGTSHYEEFADPHEAVKGADLVT
CCCCHHHHHHHHHHHEEEEEEEECCCCCCCCHHHCCCCCCCHHHHHCCHHHHHCCCCCEE
TDVWTSMGFEAETEERKRDFADFRVDAEMMSHTRKDALFMHCLPAHRGEEVAAEVIDGPQ
HHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
SVVWDEAENRLHTQKALIEYLLLGRLDNA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA