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The map label for this gene is argD [H]

Identifier: 82702170

GI number: 82702170

Start: 1204239

End: 1205411

Strand: Direct

Name: argD [H]

Synonym: Nmul_A1041

Alternate gene names: 82702170

Gene position: 1204239-1205411 (Clockwise)

Preceding gene: 82702169

Following gene: 82702171

Centisome position: 37.82

GC content: 55.33

Gene sequence:

>1173_bases
ATGTCGAATTTGATGAACACTTACCTGCGCCTGCCCGTTACATTTGCGAGGGGGGAAGGGGTGTGGTTATGGGACGAGGA
GGGCAAGCGCTATCTCGATGCGCTTGCGGGAGTAGCGGTATGCGGGCTGGGGCATTGCCACCCGGCGCTGGCAAAGGCCC
TTTGCGACCAGGCAGGTACCCTTATCCATACTTCCAATCTCTACCATATCAGGAAGCAGGAACAACTAGGAACGAGATTG
ACCGCGCTTTCAGGCATGGACAATGCATTTTTCTGCAATTCAGGGGCGGAAGCCAATGAGGCAGCGATCAAGCTCGCGAG
GTTGTATGGACATGGGAAGAATATCGATTTGCCGACTATTATCGTCATGGAAAAATCCTTCCACGGACGTACCATGGCGA
CCCTGACCGCAAGTGGCAACCGCAAGGTGCAGGCTGGCTTCGAGCCGCTCCTCACCGGTTTTGCGCGGGTTCCCTATAAT
GATCTCGAGGCAGTGGCACAGGTTGCGGAACACAACAAGAACGTCGTTGCTATCCTGGTTGAACCTTACCAGGGGGAGGG
GGGGGTCAATGTGCCGCAGGCAAATTATCTGCAAGGTCTCCGCCACCTCTGTAACCAGAACGGCTGGCTGCTGATGCTGG
ATGAAGTACAGTGCGGAATCGGCCGCACCGGCAACTGGTTCGCTTTTCAATACAGCGGCATCACGCCCGATGTCGTCACG
CTCGCCAAAGGCCTGGGATCGGGCGTGCCGATTGGGGCCTGCCTGGCGAAAGGTATCGCGGCAAATGTCTTCAAGCCAGG
CAATCATGCCTCCACTTTCGGTGGAAACCCGCTTGCCTGCAGTGCTGCGCTCACCACGCTCGAAGTAATCGAGAAAGAAG
ATCTGCTGCGCAATGCAATGGAAGTGGGCGATTTCATGCGCAGTCTGTTCAAGGCGCAATTGGCGGATTTGCCGGAGGTC
ATTGAAATTCGCGGCCAGGGCCTGATGATAGGCATCGAGCTTTCGAAACCGTGTGGTGAACTGGTGAAGGAAGCTTTGAA
AAAAGGCCTTCTCATCAATGTAACCTCCGACAAGGTCGTGCGTCTGCTACCGCCGCTGGTGATTCAACGCAGCGAGGCTG
AGCAGGTAGTCAACATTTTATCTCCCATTGTGAAGGAATTTCTGGCAGCTTGA

Upstream 100 bases:

>100_bases
GTAAAACTAAAGGATTCCACAGAATAAACCACAATAAATTCCACCACGTCGCACGGCGGCTCATGCCGCCGTGTTGCATT
CTGATCTGGCAAATTTACCT

Downstream 100 bases:

>100_bases
GTTTTTTGCGATCGCAAAAAGTGAACGGTTGAAGTCAGCCGGCCCAAGTCTTCGCAATAGTCTTCGCAACGGACTCGCCC
CTGACACCAAAAATATGCAG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSNLMNTYLRLPVTFARGEGVWLWDEEGKRYLDALAGVAVCGLGHCHPALAKALCDQAGTLIHTSNLYHIRKQEQLGTRL
TALSGMDNAFFCNSGAEANEAAIKLARLYGHGKNIDLPTIIVMEKSFHGRTMATLTASGNRKVQAGFEPLLTGFARVPYN
DLEAVAQVAEHNKNVVAILVEPYQGEGGVNVPQANYLQGLRHLCNQNGWLLMLDEVQCGIGRTGNWFAFQYSGITPDVVT
LAKGLGSGVPIGACLAKGIAANVFKPGNHASTFGGNPLACSAALTTLEVIEKEDLLRNAMEVGDFMRSLFKAQLADLPEV
IEIRGQGLMIGIELSKPCGELVKEALKKGLLINVTSDKVVRLLPPLVIQRSEAEQVVNILSPIVKEFLAA

Sequences:

>Translated_390_residues
MSNLMNTYLRLPVTFARGEGVWLWDEEGKRYLDALAGVAVCGLGHCHPALAKALCDQAGTLIHTSNLYHIRKQEQLGTRL
TALSGMDNAFFCNSGAEANEAAIKLARLYGHGKNIDLPTIIVMEKSFHGRTMATLTASGNRKVQAGFEPLLTGFARVPYN
DLEAVAQVAEHNKNVVAILVEPYQGEGGVNVPQANYLQGLRHLCNQNGWLLMLDEVQCGIGRTGNWFAFQYSGITPDVVT
LAKGLGSGVPIGACLAKGIAANVFKPGNHASTFGGNPLACSAALTTLEVIEKEDLLRNAMEVGDFMRSLFKAQLADLPEV
IEIRGQGLMIGIELSKPCGELVKEALKKGLLINVTSDKVVRLLPPLVIQRSEAEQVVNILSPIVKEFLAA
>Mature_389_residues
SNLMNTYLRLPVTFARGEGVWLWDEEGKRYLDALAGVAVCGLGHCHPALAKALCDQAGTLIHTSNLYHIRKQEQLGTRLT
ALSGMDNAFFCNSGAEANEAAIKLARLYGHGKNIDLPTIIVMEKSFHGRTMATLTASGNRKVQAGFEPLLTGFARVPYND
LEAVAQVAEHNKNVVAILVEPYQGEGGVNVPQANYLQGLRHLCNQNGWLLMLDEVQCGIGRTGNWFAFQYSGITPDVVTL
AKGLGSGVPIGACLAKGIAANVFKPGNHASTFGGNPLACSAALTTLEVIEKEDLLRNAMEVGDFMRSLFKAQLADLPEVI
EIRGQGLMIGIELSKPCGELVKEALKKGLLINVTSDKVVRLLPPLVIQRSEAEQVVNILSPIVKEFLAA

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=392, Percent_Identity=36.4795918367347, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI284507298, Length=305, Percent_Identity=37.7049180327869, Blast_Score=201, Evalue=8e-52,
Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=32.4884792626728, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI37574042, Length=414, Percent_Identity=29.951690821256, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI24119277, Length=420, Percent_Identity=30, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI226442705, Length=414, Percent_Identity=28.743961352657, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI226442709, Length=383, Percent_Identity=29.7650130548303, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI188536080, Length=429, Percent_Identity=24.7086247086247, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI38679950, Length=429, Percent_Identity=24.7086247086247, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI38679946, Length=429, Percent_Identity=24.7086247086247, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1789759, Length=384, Percent_Identity=39.3229166666667, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1788044, Length=392, Percent_Identity=38.265306122449, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI145693181, Length=371, Percent_Identity=35.5795148247978, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1789016, Length=411, Percent_Identity=32.1167883211679, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1787560, Length=393, Percent_Identity=33.0788804071247, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1786349, Length=294, Percent_Identity=31.6326530612245, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1786991, Length=404, Percent_Identity=26.7326732673267, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25144271, Length=389, Percent_Identity=38.3033419023136, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI32564660, Length=437, Percent_Identity=31.8077803203661, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI25144274, Length=273, Percent_Identity=38.8278388278388, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71992977, Length=429, Percent_Identity=28.9044289044289, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71981843, Length=161, Percent_Identity=37.2670807453416, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17541228, Length=438, Percent_Identity=24.8858447488584, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI71992985, Length=126, Percent_Identity=34.9206349206349, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=385, Percent_Identity=37.6623376623377, Blast_Score=249, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6323470, Length=404, Percent_Identity=37.3762376237624, Blast_Score=234, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6321456, Length=432, Percent_Identity=25.462962962963, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324386, Length=424, Percent_Identity=21.9339622641509, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357415, Length=387, Percent_Identity=36.6925064599483, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI28574759, Length=437, Percent_Identity=30.8924485125858, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI161085790, Length=369, Percent_Identity=32.520325203252, Blast_Score=187, Evalue=8e-48,
Organism=Drosophila melanogaster, GI21356575, Length=412, Percent_Identity=29.8543689320388, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281366494, Length=425, Percent_Identity=24, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24667139, Length=425, Percent_Identity=24, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24667143, Length=425, Percent_Identity=24, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42015; Mature: 41884

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLMNTYLRLPVTFARGEGVWLWDEEGKRYLDALAGVAVCGLGHCHPALAKALCDQAGT
CCHHHHHHHHCCEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
LIHTSNLYHIRKQEQLGTRLTALSGMDNAFFCNSGAEANEAAIKLARLYGHGKNIDLPTI
EEEECCEEEEHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCEE
IVMEKSFHGRTMATLTASGNRKVQAGFEPLLTGFARVPYNDLEAVAQVAEHNKNVVAILV
EEEECCCCCCEEEEEEECCCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEE
EPYQGEGGVNVPQANYLQGLRHLCNQNGWLLMLDEVQCGIGRTGNWFAFQYSGITPDVVT
ECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHH
LAKGLGSGVPIGACLAKGIAANVFKPGNHASTFGGNPLACSAALTTLEVIEKEDLLRNAM
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EVGDFMRSLFKAQLADLPEVIEIRGQGLMIGIELSKPCGELVKEALKKGLLINVTSDKVV
HHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCEEEEECCHHHH
RLLPPLVIQRSEAEQVVNILSPIVKEFLAA
HHCCHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNLMNTYLRLPVTFARGEGVWLWDEEGKRYLDALAGVAVCGLGHCHPALAKALCDQAGT
CHHHHHHHHCCEEEECCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
LIHTSNLYHIRKQEQLGTRLTALSGMDNAFFCNSGAEANEAAIKLARLYGHGKNIDLPTI
EEEECCEEEEHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCEE
IVMEKSFHGRTMATLTASGNRKVQAGFEPLLTGFARVPYNDLEAVAQVAEHNKNVVAILV
EEEECCCCCCEEEEEEECCCCEEECCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEE
EPYQGEGGVNVPQANYLQGLRHLCNQNGWLLMLDEVQCGIGRTGNWFAFQYSGITPDVVT
ECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEEEECCCCHHHHH
LAKGLGSGVPIGACLAKGIAANVFKPGNHASTFGGNPLACSAALTTLEVIEKEDLLRNAM
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EVGDFMRSLFKAQLADLPEVIEIRGQGLMIGIELSKPCGELVKEALKKGLLINVTSDKVV
HHHHHHHHHHHHHHHCCCHHHHHCCCEEEEEEECCCHHHHHHHHHHHCCEEEEECCHHHH
RLLPPLVIQRSEAEQVVNILSPIVKEFLAA
HHCCHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]