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The map label for this gene is speA [H]

Identifier: 82702169

GI number: 82702169

Start: 1202564

End: 1204138

Strand: Direct

Name: speA [H]

Synonym: Nmul_A1040

Alternate gene names: 82702169

Gene position: 1202564-1204138 (Clockwise)

Preceding gene: 82702166

Following gene: 82702170

Centisome position: 37.77

GC content: 53.9

Gene sequence:

>1575_bases
ATGTACCGGATTTTGAATGCCCAGCTTCAGGAAAAAGCGCGCACGCCTTTTTACGATCAACTCAAAAGTTATGTATTGAT
GGCAAAGGATGCCTGGCATACACCTGGGCATTCTTCAGGCGATTCGTTGCGGGACAGTCCCTGGGCCAGCGATTTCTACC
AGTTTATCGGCGAGCATATTTTTCGCGCAGATCTGTCGGTGTCGGTGCCCATGCTCGATTCGCTCATGGAACCTTCCGGG
GTCATTGCCGAAGCGCAGAAGATTGCGGCAAAGGCGTTTGGCGCGCGCCGCACTTTTTTTGCCACAAATGGCACTTCCAC
CGCCAACAAGGTGATATTCCAGACGTTGCTCGCTCCTGGCGAAAAGCTGCTGCTGGATCGGAACTGCCATAAATCGGTTC
ATCACGGAGTCGTGCTATCCGGCGCCCATCCCATCTATCTCAACTCCTCGGTAAACAAGAAATTCGGGGTTTATGGGCCG
GTGCCCAAGCAGACACTGTTCAGGGCAATCGAAGAACATCCCGATGCCCAGGCGCTCATACTCACGAGTTGCACCTATGA
TGGTTTCCGCTATGACCTGCCTCCGATCATAGAGGCCGCGCATGCCAAAGGCATCAAGGTGATCATCGATGAAGCCTGGT
ACGGGTTCGCCCGCTTTCATCCGGCTTTCCGTCCCACCGCCCTGGAAGCAGGCGCAGATTATGCTACTCAAAGTACACAC
AAGGTGCTGTCGGCTTTTTCCCAGTCCAGCATGATTCATATCAATGATCCCGAATTCAACGAGCATCTGTTTCGGGAAAA
TTTCAACATGCATACTTCCACCAGCCCGCAGTACAGCATGATTGCAAGTCTCGACGTGGCGCGCAAACAGGTGGTGATGG
AGGGATACAAGCTATTGTCGCGCACGCTGGAGCTGGCGAAGGAAGTACGTGAGCAAATCAATTCGACCGGCGTGTTTCGC
GTACTGGAACTGACGGATCTGCTGCCTGACGAGGTGAAGAACGACAATATCCAGCTCGATTCGACCAAGGTCACCGTCGA
TATTTCGCATTGTGGCTTTACGGTGGAAGATTTGGTCCGGGAACTGTTCGAGCGATATAACATTCAGGTGGAAAAATCCA
CTTTCAATACGCTCACTCTGCTGCTGACCATCGGTACCACGCGCAGCAAGGTATCGCGCCTTTACGATGCTCTCATGCGC
ATCGCACGCGAGGGCAGGGCGCCCCGCAGACTCTACCAGATCCCGGAGCTTCCGGGATTTACTGAATTGAAGTATCTGCC
GCGGGATGCCTTTTACTGCGGCGGCGAGATCGTTCCGTTGCTCGACGAGCAGGAGCGGATAAATGATAGCCTGAAAGGGA
AGGTCTGCGCGGATCAGATCACGCCTTACCCCCCGGGTATTCCGGTCCTGGTGCCAGGCCAGACCATCACGTCCGGGGTG
GTGCAATATCTAGTCAGCATGCTACGATCGCAGAAACGGGTGGAAGTGCACGGGATCGTTTATGACGGCTATCTGCCGTG
TTTGAGGCTGTTGAGCGACGTCGAGGAAAAGAGCTTGAAAAAGCTTGCAAAATAG

Upstream 100 bases:

>100_bases
TATCCTGATCGCGCAGGAGAAAGAGGATGAGGTGGTGGATGCGCTGTTTTCTGAAACCGTGGATGGTTATTTCTATCGGG
AAGAGCGTGATTACCGGGGC

Downstream 100 bases:

>100_bases
GTAAAACTAAAGGATTCCACAGAATAAACCACAATAAATTCCACCACGTCGCACGGCGGCTCATGCCGCCGTGTTGCATT
CTGATCTGGCAAATTTACCT

Product: arginine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MYRILNAQLQEKARTPFYDQLKSYVLMAKDAWHTPGHSSGDSLRDSPWASDFYQFIGEHIFRADLSVSVPMLDSLMEPSG
VIAEAQKIAAKAFGARRTFFATNGTSTANKVIFQTLLAPGEKLLLDRNCHKSVHHGVVLSGAHPIYLNSSVNKKFGVYGP
VPKQTLFRAIEEHPDAQALILTSCTYDGFRYDLPPIIEAAHAKGIKVIIDEAWYGFARFHPAFRPTALEAGADYATQSTH
KVLSAFSQSSMIHINDPEFNEHLFRENFNMHTSTSPQYSMIASLDVARKQVVMEGYKLLSRTLELAKEVREQINSTGVFR
VLELTDLLPDEVKNDNIQLDSTKVTVDISHCGFTVEDLVRELFERYNIQVEKSTFNTLTLLLTIGTTRSKVSRLYDALMR
IAREGRAPRRLYQIPELPGFTELKYLPRDAFYCGGEIVPLLDEQERINDSLKGKVCADQITPYPPGIPVLVPGQTITSGV
VQYLVSMLRSQKRVEVHGIVYDGYLPCLRLLSDVEEKSLKKLAK

Sequences:

>Translated_524_residues
MYRILNAQLQEKARTPFYDQLKSYVLMAKDAWHTPGHSSGDSLRDSPWASDFYQFIGEHIFRADLSVSVPMLDSLMEPSG
VIAEAQKIAAKAFGARRTFFATNGTSTANKVIFQTLLAPGEKLLLDRNCHKSVHHGVVLSGAHPIYLNSSVNKKFGVYGP
VPKQTLFRAIEEHPDAQALILTSCTYDGFRYDLPPIIEAAHAKGIKVIIDEAWYGFARFHPAFRPTALEAGADYATQSTH
KVLSAFSQSSMIHINDPEFNEHLFRENFNMHTSTSPQYSMIASLDVARKQVVMEGYKLLSRTLELAKEVREQINSTGVFR
VLELTDLLPDEVKNDNIQLDSTKVTVDISHCGFTVEDLVRELFERYNIQVEKSTFNTLTLLLTIGTTRSKVSRLYDALMR
IAREGRAPRRLYQIPELPGFTELKYLPRDAFYCGGEIVPLLDEQERINDSLKGKVCADQITPYPPGIPVLVPGQTITSGV
VQYLVSMLRSQKRVEVHGIVYDGYLPCLRLLSDVEEKSLKKLAK
>Mature_524_residues
MYRILNAQLQEKARTPFYDQLKSYVLMAKDAWHTPGHSSGDSLRDSPWASDFYQFIGEHIFRADLSVSVPMLDSLMEPSG
VIAEAQKIAAKAFGARRTFFATNGTSTANKVIFQTLLAPGEKLLLDRNCHKSVHHGVVLSGAHPIYLNSSVNKKFGVYGP
VPKQTLFRAIEEHPDAQALILTSCTYDGFRYDLPPIIEAAHAKGIKVIIDEAWYGFARFHPAFRPTALEAGADYATQSTH
KVLSAFSQSSMIHINDPEFNEHLFRENFNMHTSTSPQYSMIASLDVARKQVVMEGYKLLSRTLELAKEVREQINSTGVFR
VLELTDLLPDEVKNDNIQLDSTKVTVDISHCGFTVEDLVRELFERYNIQVEKSTFNTLTLLLTIGTTRSKVSRLYDALMR
IAREGRAPRRLYQIPELPGFTELKYLPRDAFYCGGEIVPLLDEQERINDSLKGKVCADQITPYPPGIPVLVPGQTITSGV
VQYLVSMLRSQKRVEVHGIVYDGYLPCLRLLSDVEEKSLKKLAK

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=540, Percent_Identity=30.3703703703704, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1786384, Length=547, Percent_Identity=30.8957952468007, Blast_Score=221, Evalue=7e-59,
Organism=Escherichia coli, GI221142684, Length=587, Percent_Identity=27.427597955707, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87082193, Length=336, Percent_Identity=35.7142857142857, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1786909, Length=592, Percent_Identity=27.3648648648649, Blast_Score=170, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 58923; Mature: 58923

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRILNAQLQEKARTPFYDQLKSYVLMAKDAWHTPGHSSGDSLRDSPWASDFYQFIGEHI
CCCCHHHHHHHHHCCCHHHHHHHHEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FRADLSVSVPMLDSLMEPSGVIAEAQKIAAKAFGARRTFFATNGTSTANKVIFQTLLAPG
HHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCC
EKLLLDRNCHKSVHHGVVLSGAHPIYLNSSVNKKFGVYGPVPKQTLFRAIEEHPDAQALI
HHEEECCCHHHHHHCCEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEE
LTSCTYDGFRYDLPPIIEAAHAKGIKVIIDEAWYGFARFHPAFRPTALEAGADYATQSTH
EEEECCCCCCCCCCHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCCCHHHCCCCHHHHHHH
KVLSAFSQSSMIHINDPEFNEHLFRENFNMHTSTSPQYSMIASLDVARKQVVMEGYKLLS
HHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RTLELAKEVREQINSTGVFRVLELTDLLPDEVKNDNIQLDSTKVTVDISHCGFTVEDLVR
HHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHCCCCEEEECEEEEEEECCCCCCHHHHHH
ELFERYNIQVEKSTFNTLTLLLTIGTTRSKVSRLYDALMRIAREGRAPRRLYQIPELPGF
HHHHHHCCEEEECHHCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
TELKYLPRDAFYCGGEIVPLLDEQERINDSLKGKVCADQITPYPPGIPVLVPGQTITSGV
CHHHCCCCCCEECCCCEEECCCCHHHHCHHHCCCEEHHCCCCCCCCCCEEECCCHHHHHH
VQYLVSMLRSQKRVEVHGIVYDGYLPCLRLLSDVEEKSLKKLAK
HHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYRILNAQLQEKARTPFYDQLKSYVLMAKDAWHTPGHSSGDSLRDSPWASDFYQFIGEHI
CCCCHHHHHHHHHCCCHHHHHHHHEEHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FRADLSVSVPMLDSLMEPSGVIAEAQKIAAKAFGARRTFFATNGTSTANKVIFQTLLAPG
HHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCC
EKLLLDRNCHKSVHHGVVLSGAHPIYLNSSVNKKFGVYGPVPKQTLFRAIEEHPDAQALI
HHEEECCCHHHHHHCCEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEE
LTSCTYDGFRYDLPPIIEAAHAKGIKVIIDEAWYGFARFHPAFRPTALEAGADYATQSTH
EEEECCCCCCCCCCHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCCCHHHCCCCHHHHHHH
KVLSAFSQSSMIHINDPEFNEHLFRENFNMHTSTSPQYSMIASLDVARKQVVMEGYKLLS
HHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RTLELAKEVREQINSTGVFRVLELTDLLPDEVKNDNIQLDSTKVTVDISHCGFTVEDLVR
HHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHCCCCEEEECEEEEEEECCCCCCHHHHHH
ELFERYNIQVEKSTFNTLTLLLTIGTTRSKVSRLYDALMRIAREGRAPRRLYQIPELPGF
HHHHHHCCEEEECHHCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCC
TELKYLPRDAFYCGGEIVPLLDEQERINDSLKGKVCADQITPYPPGIPVLVPGQTITSGV
CHHHCCCCCCEECCCCEEECCCCHHHHCHHHCCCEEHHCCCCCCCCCCEEECCCHHHHHH
VQYLVSMLRSQKRVEVHGIVYDGYLPCLRLLSDVEEKSLKKLAK
HHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]