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The map label for this gene is ackA [H]

Identifier: 82702121

GI number: 82702121

Start: 1150919

End: 1152049

Strand: Direct

Name: ackA [H]

Synonym: Nmul_A0992

Alternate gene names: 82702121

Gene position: 1150919-1152049 (Clockwise)

Preceding gene: 82702120

Following gene: 82702122

Centisome position: 36.14

GC content: 56.23

Gene sequence:

>1131_bases
ATGCGTTCCGCTCAAGCCCTTGCCATGAAAATTTTGACGGTCAACACAGGCAGCTCATCGGTACGCCTGGCAGCATTCCT
TCACCATCAGGAAAAGCTGACGGAGCTTGTGAGTGTCAGGGAAGATTCCGGTGGTGAGCCGGAAGATATCCTCCAGGAAT
TCGTGCAGGTCCACAAACTTGGCAAGGTGAATGTCGTGGCGCATCGCGTCGTGCATGGAGGCATGCGTCTTACTTCCCCT
TGCGTGATCGATCGCGACGTGGAGAGGGAAATCGAATGTCTTGCGCCGCTTGCGCCCTTGCATAACCCCGTCGCACTGGA
GTGGATACGTGCCGCCAAGGAAGTATTCGGTATTCATATGCCGCAAGTTGCAGTATTCGACACCGCATTTTTTACCCATC
TGCCGACAGTTGCGCAAACTTACGCAATTCCGCATGAGCTGACCGGAAAGTACGCATTGCGGCGGTACGGTTTTCACGGA
CTGGCGCACCAGGCTATGTGGCAGGCTTGGCGCGATCAACATCCGGACTTTGTGCAAAATGGAAAAATCATTTCGATGCA
GTTCGGAGCAGGTTGCTCGATCACGGCGACAGAGAAAGGATTGCCTCGCGATACTTCCATGGGATTCTCGCCTCTGGAGG
GATTGATGATGGCGACGCGCTCGGGCGACCTGGACCCCGGTCTGATGACGTTTTTGCAGCGGCAGGAGAGCTTGGCGCCG
GAGCAGATGGATCGGCTGCTGAATGAGCAGTCCGGTTTATCGGGAGTGTCGGGAATCAGCGCCGATATCCGGGAACTGCT
GAAGTCGAAAGACGAATACGCTGGGCTGGCGGTCGAGCTGTACTGTTACCGGGCGCGTAAATATCTGGGCGCTTATCTTG
CCGTGCTGGGCGGGGCAAATGCAGTGATTTTTGGCGGGGGCGTGGGGGAGAACGTTCCAGTCGTGCGGGAAAAGATTCTG
GCAGGAATGGAATGGTGCGGAATCCATCTCGACGCGAAAAAGAACAGCGATGCGAGCGGGATGTCATGCATCAGTAGCGA
AGCGAGTCGGGTCGAAGTGTGGGTGGCTCCCGTGAATGAGGCGACAATCCTCGCGCAGGAAGCAGAGGCAGTTATTTCCA
GTCGTGGCTAG

Upstream 100 bases:

>100_bases
CCTTTATGAAACCCCTTGCGATGTGCTCGTAGTCAACCCGTAATATGATGCCTTAATATGATTTTGTAATTCTCAAGCCC
TGATGGAGCGCTGGATCTTT

Downstream 100 bases:

>100_bases
CCTTTGCCCCAGTGCCTGGATTCTTCGGCAGTAACCAGTGTCCGGAAAAAGGAGGATTCAATATGAACCGTGCTTCGCCT
GCAGTAAAAACCGAAAGCAA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MRSAQALAMKILTVNTGSSSVRLAAFLHHQEKLTELVSVREDSGGEPEDILQEFVQVHKLGKVNVVAHRVVHGGMRLTSP
CVIDRDVEREIECLAPLAPLHNPVALEWIRAAKEVFGIHMPQVAVFDTAFFTHLPTVAQTYAIPHELTGKYALRRYGFHG
LAHQAMWQAWRDQHPDFVQNGKIISMQFGAGCSITATEKGLPRDTSMGFSPLEGLMMATRSGDLDPGLMTFLQRQESLAP
EQMDRLLNEQSGLSGVSGISADIRELLKSKDEYAGLAVELYCYRARKYLGAYLAVLGGANAVIFGGGVGENVPVVREKIL
AGMEWCGIHLDAKKNSDASGMSCISSEASRVEVWVAPVNEATILAQEAEAVISSRG

Sequences:

>Translated_376_residues
MRSAQALAMKILTVNTGSSSVRLAAFLHHQEKLTELVSVREDSGGEPEDILQEFVQVHKLGKVNVVAHRVVHGGMRLTSP
CVIDRDVEREIECLAPLAPLHNPVALEWIRAAKEVFGIHMPQVAVFDTAFFTHLPTVAQTYAIPHELTGKYALRRYGFHG
LAHQAMWQAWRDQHPDFVQNGKIISMQFGAGCSITATEKGLPRDTSMGFSPLEGLMMATRSGDLDPGLMTFLQRQESLAP
EQMDRLLNEQSGLSGVSGISADIRELLKSKDEYAGLAVELYCYRARKYLGAYLAVLGGANAVIFGGGVGENVPVVREKIL
AGMEWCGIHLDAKKNSDASGMSCISSEASRVEVWVAPVNEATILAQEAEAVISSRG
>Mature_376_residues
MRSAQALAMKILTVNTGSSSVRLAAFLHHQEKLTELVSVREDSGGEPEDILQEFVQVHKLGKVNVVAHRVVHGGMRLTSP
CVIDRDVEREIECLAPLAPLHNPVALEWIRAAKEVFGIHMPQVAVFDTAFFTHLPTVAQTYAIPHELTGKYALRRYGFHG
LAHQAMWQAWRDQHPDFVQNGKIISMQFGAGCSITATEKGLPRDTSMGFSPLEGLMMATRSGDLDPGLMTFLQRQESLAP
EQMDRLLNEQSGLSGVSGISADIRELLKSKDEYAGLAVELYCYRARKYLGAYLAVLGGANAVIFGGGVGENVPVVREKIL
AGMEWCGIHLDAKKNSDASGMSCISSEASRVEVWVAPVNEATILAQEAEAVISSRG

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=315, Percent_Identity=39.0476190476191, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI145693184, Length=387, Percent_Identity=33.0749354005168, Blast_Score=201, Evalue=9e-53,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 40981; Mature: 40981

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAQALAMKILTVNTGSSSVRLAAFLHHQEKLTELVSVREDSGGEPEDILQEFVQVHKL
CCCHHEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GKVNVVAHRVVHGGMRLTSPCVIDRDVEREIECLAPLAPLHNPVALEWIRAAKEVFGIHM
CCHHHHHHHHHHCCCEECCCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
PQVAVFDTAFFTHLPTVAQTYAIPHELTGKYALRRYGFHGLAHQAMWQAWRDQHPDFVQN
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHC
GKIISMQFGAGCSITATEKGLPRDTSMGFSPLEGLMMATRSGDLDPGLMTFLQRQESLAP
CEEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCH
EQMDRLLNEQSGLSGVSGISADIRELLKSKDEYAGLAVELYCYRARKYLGAYLAVLGGAN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
AVIFGGGVGENVPVVREKILAGMEWCGIHLDAKKNSDASGMSCISSEASRVEVWVAPVNE
EEEECCCCCCCCHHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHCCCCEEEEEEEECCC
ATILAQEAEAVISSRG
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSAQALAMKILTVNTGSSSVRLAAFLHHQEKLTELVSVREDSGGEPEDILQEFVQVHKL
CCCHHEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
GKVNVVAHRVVHGGMRLTSPCVIDRDVEREIECLAPLAPLHNPVALEWIRAAKEVFGIHM
CCHHHHHHHHHHCCCEECCCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
PQVAVFDTAFFTHLPTVAQTYAIPHELTGKYALRRYGFHGLAHQAMWQAWRDQHPDFVQN
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHC
GKIISMQFGAGCSITATEKGLPRDTSMGFSPLEGLMMATRSGDLDPGLMTFLQRQESLAP
CEEEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCH
EQMDRLLNEQSGLSGVSGISADIRELLKSKDEYAGLAVELYCYRARKYLGAYLAVLGGAN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
AVIFGGGVGENVPVVREKILAGMEWCGIHLDAKKNSDASGMSCISSEASRVEVWVAPVNE
EEEECCCCCCCCHHHHHHHHHCCHHHEEEEECCCCCCCCCHHHHHCCCCEEEEEEEECCC
ATILAQEAEAVISSRG
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA