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The map label for this gene is secA

Identifier: 82702053

GI number: 82702053

Start: 1051694

End: 1053694

Strand: Reverse

Name: secA

Synonym: Nmul_A0924

Alternate gene names: 82702053

Gene position: 1053694-1051694 (Counterclockwise)

Preceding gene: 82702054

Following gene: 82702052

Centisome position: 33.09

GC content: 51.37

Gene sequence:

>2001_bases
ATGTCTAAAGCCTTGCTTGCTGCCTGGAGAATAAACAGCCTTGCCCCAGCACCTTATCCGGAGCGGCTGGATACGAATGA
TAATGCTCTGGATCGCTTTTTAGGCTCATCGCTTGGGCAAGCGCGGTTATGGGCATCCCATCTTCGACTTAAACGCTTGA
GGAGCTTTGCGGACAAGGTTGTGCATCGAAGCAACGCTCTCTCCGCTTTATCTGAAGCAGAGCTCGCTGCGTGCGTGGAC
GATCTTAGGGTGAAGCTTGCCCGCCAAGGGTTAACGGAAGATCTGACGATTGAAGTTTTTTCATTGGTAAGGGAAGTTTG
CGGCCGTAAACTGGGATTGCGGCATTTTCCGGTGCAGCTGATCGGTGGCCGGGTAATATTGGCCGGGAAGCTGGCGGAGA
TGCAAACCGGAGAGGGTAAATCACTCACCGCGGTACTTCCCGCGATAGCGGTGGCCCTGTCAGGTTTACCAGTTCATGTA
ATTACGGTAAATGAATATCTTGTCCGGCGTGATGCCAGATTTATGCGACCGGTGTATGAGTTTTTTGGCCTTGACGTGGG
AATGGTGGTTCCAGATCAGGATCCGGAAACACGACGGAATGCCTATGGTTGTGATGTCACCTATTGCGTCAACAAAGATC
TAGTATTCGATTATCTGCGTGACCGGATTGACTCTAATCGCGATGTCTCGGATGCCCGCCGCGCTGTAGCTCGCCTGTTC
AGGGGTGACGAGAATTCCAGAGCTTACTTACGTGGGTTATTTTTTGGGATTGTCGATGAAGCAGACAGCGTGCTCATTGA
CGAGGCGCGAACCCCGCTCATCATTTCCAGCAGTGTGTCTGACAAGCAAGGAGTCGATGACTACCGGAGAGCATTGGATT
TTTGCCGACAACTTCGAGATGGACTGCATTTTCGGATTTTTGCTGCTGATAAGTTGATCCAGTTGACTCCTGCCGGTCGT
GATCACATTACGAACATCTGTGGCAACCTTCCTGGCGTTTGGCAAGTTGCACGCGCCCGCTTCGAGTTGATCGAGCAGGC
CCTGGCAGCCCAGTTGCTGTACATGCGCGACAAGCACTACATCGTAAAGGATGAGAAGGTGCAGATTGTAGATGAATATA
CCGGAAGAGTCATGTCGGATCGGACTTGGGAAAGCGGATTGCACCAGATGATTGAAGTAAAGGAAGGATGTGCGCTTACC
GATCGTCGTAAAACCATTTCTCGCATAACATATCAGCGGTTTTTTAGACGATATCTGCGGCTTGGCGGTATGACTGGCAC
CGCAGCCGAGGTGGTGGGCGAGTTAAGTGCCATATTCGGGCTGGACGTGCTGCGAATTCCAACTAATCGTGCGGTACAGC
GAAAGAATTTGGGAACGAGAATCTTTCTCGATACCGCATCCCGTTGGGATGCGGTACTGAAAAGTATACGGCGTGTTCGC
GATGAAGGTCGTCCCGTTCTGATTGGAACGCGTTCGGTAGCTGCTTCGGAGCATTTGAGTAGCCTGCTCAAGACAGAAGG
AATCGAACATAGCGTGATTAATGCTCGCCAGGATGAAGACGAGGCAACTGTCGTTGAGCAGGCCGGCCGCGTTGGTCGTG
TCACAGTCGCGACGAATATGGCGGGGCGCGGTACTGATATTAAATTGGAATCTGGCGTATCGGATAGAGGAGGATTGCAC
GTAATTTTGTCTGAGTTCCACGAATCGCCCCGCATCGACCGACAACTTTATGGACGTGCTGGACGCCAGGGGGATAAGGG
AAGTTACGAATCCATTGTCTCCTTGGAAGACGAGCTATTTGTTCTATTTTCGGGAGAGATGGCTCGTAGGGTTATGAGCA
ATTCAAGTTTCAGTAATGTAATAACCGGCATGAAAGCAAAACTGCTGCGGGGATCGGCACAACGATCATCAGAACGGTAT
TACTCGAGAATACGTCGCCAGACTGTGCTGGAAGATCAACGACTAGCGAAGATGCTGGCTTTTGCGGGACGTGGAGAGTG
A

Upstream 100 bases:

>100_bases
TCACTGGGAGCGCGTGTCCATGTCCGTTTTGATCTCGCTCCAGAACCCCTGGCATTCCGCTGGTACCGGGCATCGCGGCA
ACTCCTGTTATCGAACTTCA

Downstream 100 bases:

>100_bases
TGATATATCTCGATTGGAAGGAATCAAACGTTGACTATTAATGTGAGGCGCTTTTGGGCACAAGTTACGTTTGCCTGCGT
ATCCTCTTGGGGGGCGGCAT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MSKALLAAWRINSLAPAPYPERLDTNDNALDRFLGSSLGQARLWASHLRLKRLRSFADKVVHRSNALSALSEAELAACVD
DLRVKLARQGLTEDLTIEVFSLVREVCGRKLGLRHFPVQLIGGRVILAGKLAEMQTGEGKSLTAVLPAIAVALSGLPVHV
ITVNEYLVRRDARFMRPVYEFFGLDVGMVVPDQDPETRRNAYGCDVTYCVNKDLVFDYLRDRIDSNRDVSDARRAVARLF
RGDENSRAYLRGLFFGIVDEADSVLIDEARTPLIISSSVSDKQGVDDYRRALDFCRQLRDGLHFRIFAADKLIQLTPAGR
DHITNICGNLPGVWQVARARFELIEQALAAQLLYMRDKHYIVKDEKVQIVDEYTGRVMSDRTWESGLHQMIEVKEGCALT
DRRKTISRITYQRFFRRYLRLGGMTGTAAEVVGELSAIFGLDVLRIPTNRAVQRKNLGTRIFLDTASRWDAVLKSIRRVR
DEGRPVLIGTRSVAASEHLSSLLKTEGIEHSVINARQDEDEATVVEQAGRVGRVTVATNMAGRGTDIKLESGVSDRGGLH
VILSEFHESPRIDRQLYGRAGRQGDKGSYESIVSLEDELFVLFSGEMARRVMSNSSFSNVITGMKAKLLRGSAQRSSERY
YSRIRRQTVLEDQRLAKMLAFAGRGE

Sequences:

>Translated_666_residues
MSKALLAAWRINSLAPAPYPERLDTNDNALDRFLGSSLGQARLWASHLRLKRLRSFADKVVHRSNALSALSEAELAACVD
DLRVKLARQGLTEDLTIEVFSLVREVCGRKLGLRHFPVQLIGGRVILAGKLAEMQTGEGKSLTAVLPAIAVALSGLPVHV
ITVNEYLVRRDARFMRPVYEFFGLDVGMVVPDQDPETRRNAYGCDVTYCVNKDLVFDYLRDRIDSNRDVSDARRAVARLF
RGDENSRAYLRGLFFGIVDEADSVLIDEARTPLIISSSVSDKQGVDDYRRALDFCRQLRDGLHFRIFAADKLIQLTPAGR
DHITNICGNLPGVWQVARARFELIEQALAAQLLYMRDKHYIVKDEKVQIVDEYTGRVMSDRTWESGLHQMIEVKEGCALT
DRRKTISRITYQRFFRRYLRLGGMTGTAAEVVGELSAIFGLDVLRIPTNRAVQRKNLGTRIFLDTASRWDAVLKSIRRVR
DEGRPVLIGTRSVAASEHLSSLLKTEGIEHSVINARQDEDEATVVEQAGRVGRVTVATNMAGRGTDIKLESGVSDRGGLH
VILSEFHESPRIDRQLYGRAGRQGDKGSYESIVSLEDELFVLFSGEMARRVMSNSSFSNVITGMKAKLLRGSAQRSSERY
YSRIRRQTVLEDQRLAKMLAFAGRGE
>Mature_665_residues
SKALLAAWRINSLAPAPYPERLDTNDNALDRFLGSSLGQARLWASHLRLKRLRSFADKVVHRSNALSALSEAELAACVDD
LRVKLARQGLTEDLTIEVFSLVREVCGRKLGLRHFPVQLIGGRVILAGKLAEMQTGEGKSLTAVLPAIAVALSGLPVHVI
TVNEYLVRRDARFMRPVYEFFGLDVGMVVPDQDPETRRNAYGCDVTYCVNKDLVFDYLRDRIDSNRDVSDARRAVARLFR
GDENSRAYLRGLFFGIVDEADSVLIDEARTPLIISSSVSDKQGVDDYRRALDFCRQLRDGLHFRIFAADKLIQLTPAGRD
HITNICGNLPGVWQVARARFELIEQALAAQLLYMRDKHYIVKDEKVQIVDEYTGRVMSDRTWESGLHQMIEVKEGCALTD
RRKTISRITYQRFFRRYLRLGGMTGTAAEVVGELSAIFGLDVLRIPTNRAVQRKNLGTRIFLDTASRWDAVLKSIRRVRD
EGRPVLIGTRSVAASEHLSSLLKTEGIEHSVINARQDEDEATVVEQAGRVGRVTVATNMAGRGTDIKLESGVSDRGGLHV
ILSEFHESPRIDRQLYGRAGRQGDKGSYESIVSLEDELFVLFSGEMARRVMSNSSFSNVITGMKAKLLRGSAQRSSERYY
SRIRRQTVLEDQRLAKMLAFAGRGE

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=605, Percent_Identity=38.8429752066116, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA2_NITMU (Q2YAJ4)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411619.1
- ProteinModelPortal:   Q2YAJ4
- SMR:   Q2YAJ4
- STRING:   Q2YAJ4
- GeneID:   3786469
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0924
- eggNOG:   COG0653
- HOGENOM:   HBG284200
- OMA:   RVMPDRS
- ProtClustDB:   PRK12898
- BioCyc:   NMUL323848:NMUL_A0924-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR001650
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958

Pfam domain/function: PF00271 Helicase_C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; SSF81767 SecA_PP_bd

EC number: NA

Molecular weight: Translated: 74709; Mature: 74577

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD; PS00579 RIBOSOMAL_L29

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKALLAAWRINSLAPAPYPERLDTNDNALDRFLGSSLGQARLWASHLRLKRLRSFADKV
CCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VHRSNALSALSEAELAACVDDLRVKLARQGLTEDLTIEVFSLVREVCGRKLGLRHFPVQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
IGGRVILAGKLAEMQTGEGKSLTAVLPAIAVALSGLPVHVITVNEYLVRRDARFMRPVYE
HCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHH
FFGLDVGMVVPDQDPETRRNAYGCDVTYCVNKDLVFDYLRDRIDSNRDVSDARRAVARLF
HHCCCCEEECCCCCCHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RGDENSRAYLRGLFFGIVDEADSVLIDEARTPLIISSSVSDKQGVDDYRRALDFCRQLRD
CCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHC
GLHFRIFAADKLIQLTPAGRDHITNICGNLPGVWQVARARFELIEQALAAQLLYMRDKHY
CCEEEEEECCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IVKDEKVQIVDEYTGRVMSDRTWESGLHQMIEVKEGCALTDRRKTISRITYQRFFRRYLR
EECCCCEEHHHHHHCCHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LGGMTGTAAEVVGELSAIFGLDVLRIPTNRAVQRKNLGTRIFLDTASRWDAVLKSIRRVR
HCCCCCHHHHHHHHHHHHHCCHHEECCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
DEGRPVLIGTRSVAASEHLSSLLKTEGIEHSVINARQDEDEATVVEQAGRVGRVTVATNM
HCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHCCCCCEEEEEECC
AGRGTDIKLESGVSDRGGLHVILSEFHESPRIDRQLYGRAGRQGDKGSYESIVSLEDELF
CCCCCCEEECCCCCCCCCEEHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHCCCCCEE
VLFSGEMARRVMSNSSFSNVITGMKAKLLRGSAQRSSERYYSRIRRQTVLEDQRLAKMLA
EEECCHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGRGE
HCCCCC
>Mature Secondary Structure 
SKALLAAWRINSLAPAPYPERLDTNDNALDRFLGSSLGQARLWASHLRLKRLRSFADKV
CCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VHRSNALSALSEAELAACVDDLRVKLARQGLTEDLTIEVFSLVREVCGRKLGLRHFPVQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
IGGRVILAGKLAEMQTGEGKSLTAVLPAIAVALSGLPVHVITVNEYLVRRDARFMRPVYE
HCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHH
FFGLDVGMVVPDQDPETRRNAYGCDVTYCVNKDLVFDYLRDRIDSNRDVSDARRAVARLF
HHCCCCEEECCCCCCHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
RGDENSRAYLRGLFFGIVDEADSVLIDEARTPLIISSSVSDKQGVDDYRRALDFCRQLRD
CCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHC
GLHFRIFAADKLIQLTPAGRDHITNICGNLPGVWQVARARFELIEQALAAQLLYMRDKHY
CCEEEEEECCCEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
IVKDEKVQIVDEYTGRVMSDRTWESGLHQMIEVKEGCALTDRRKTISRITYQRFFRRYLR
EECCCCEEHHHHHHCCHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LGGMTGTAAEVVGELSAIFGLDVLRIPTNRAVQRKNLGTRIFLDTASRWDAVLKSIRRVR
HCCCCCHHHHHHHHHHHHHCCHHEECCCCHHHHHHCCCCEEEEECHHHHHHHHHHHHHHH
DEGRPVLIGTRSVAASEHLSSLLKTEGIEHSVINARQDEDEATVVEQAGRVGRVTVATNM
HCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHCCCCCEEEEEECC
AGRGTDIKLESGVSDRGGLHVILSEFHESPRIDRQLYGRAGRQGDKGSYESIVSLEDELF
CCCCCCEEECCCCCCCCCEEHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHCCCCCEE
VLFSGEMARRVMSNSSFSNVITGMKAKLLRGSAQRSSERYYSRIRRQTVLEDQRLAKMLA
EEECCHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGRGE
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA