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The map label for this gene is intA [H]

Identifier: 82702051

GI number: 82702051

Start: 1049014

End: 1050225

Strand: Direct

Name: intA [H]

Synonym: Nmul_A0922

Alternate gene names: 82702051

Gene position: 1049014-1050225 (Clockwise)

Preceding gene: 82702050

Following gene: 82702059

Centisome position: 32.94

GC content: 48.93

Gene sequence:

>1212_bases
ATGAGACGCCAAACGTGTAGGTTATCAGCAAAGGAAGTGTCTAACAAGAAGAAGCCAGGTTACTACTGCGATGGTGCGGG
GCTCTATCTGCAGATAAGTGACTCGGGCAGCAAGTCGTGGATATTCCGCTATACCTTGAACGGCAAGAACCGGCACATGG
GTTTAGGGCCAGTTCATACTGTCTCCCTGGCTGATGCACGCACTGCCGCCGTTCAATGCCGGCAATTGCTGCTTCGCAAA
ATGGATCCTATTACAGCACGTGATGCTGAGCACGCACAGCAGTCACTTGAAGCTGCAAGGTCAATGACTTTTTCCGAGTG
TGCTGCTCTCTATATTAAAGCCCATCGCTCCAGCTGGAAGAACACAAAACATGCCGATCAGTGGACAAATACCATCAAGA
CTTATTGCGGACCTGTCATAGGCCCGTTATCCGTCCAGGATGTCGATACGAAGCTGATTATGAAGGTGCTAGACCCGATC
TGGGAACAGAAACCGGAGACAGCCAGCCGATTACGCGGGCGTATAGAATCTGTACTTGATTGGGCTACAGTCAGAGGTTA
TCGAGAAGGAGATAATCCCGCCCGATGGCGAGGGTATCTTAGTCATGCGCTACCCTCGCTTAAAAAGAAACTCAGGGTAA
AACATCATCCGGCCTTACAGTTCAGCCAGATGGCTGAATTTATGGGATTGCTTCGAGCAGAGGAAGGCATTGCTGCAAGA
GCACTGGAATTCCTAATTCTCACAGCCGCACGAACTAGTGAGGTTATCGGTGCAAGATGGGAAGAGTTGGATCTAAAGGC
TTCGATCTGGACTATTCCAGGTACGCGCATGAAAGCGGATGACCCGCATCGAGTACCGCTTTCGGGAAGAGCTTTGGAAA
TTATCTTGAACTTGGAGAAGATAAAGCAAAGCGACTATGTATTTCCAGGGCAGAAGATCGAAAAGCCGCTAAGCAATAAC
GCCATGCTTAAGGTACTCGAACGCATGGGAAGGAATGATATAACCGTACATGGTTTTCGCTCATCATTTCGAGACTGGGC
TTCGGAATGCACAAATTTTCCAAGAGACGTATGTGAGATGGCGCTTGCCCATACGATAAGCAATAAAGCAGAAGCAGCTT
ATCGTCGAGGAGACTTGTTCGAGAAGCGGAGGGTATTGATGGAAGAGTGGGCGGGATATTGCTACGATGGCTCAGCAATT
ATGTCAAGGTAA

Upstream 100 bases:

>100_bases
GACTTGGTTTTACTTATCTTTTTTTAAATACTTGCCTTGACGTGTTCCAGGTTGTCCCATAGTATCCCAGTCTCATATGT
AGGTAGAAATGGGGGTAGAA

Downstream 100 bases:

>100_bases
TAACTATAGGGAATGCTTCTGTTCGAATCATCTGCAAGAAGTACTTGCCAGTTTAGGCTTCTATAAAAAGTCAGAGTCAG
TTGTTGAATCTAATGGAGGG

Product: Phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MRRQTCRLSAKEVSNKKKPGYYCDGAGLYLQISDSGSKSWIFRYTLNGKNRHMGLGPVHTVSLADARTAAVQCRQLLLRK
MDPITARDAEHAQQSLEAARSMTFSECAALYIKAHRSSWKNTKHADQWTNTIKTYCGPVIGPLSVQDVDTKLIMKVLDPI
WEQKPETASRLRGRIESVLDWATVRGYREGDNPARWRGYLSHALPSLKKKLRVKHHPALQFSQMAEFMGLLRAEEGIAAR
ALEFLILTAARTSEVIGARWEELDLKASIWTIPGTRMKADDPHRVPLSGRALEIILNLEKIKQSDYVFPGQKIEKPLSNN
AMLKVLERMGRNDITVHGFRSSFRDWASECTNFPRDVCEMALAHTISNKAEAAYRRGDLFEKRRVLMEEWAGYCYDGSAI
MSR

Sequences:

>Translated_403_residues
MRRQTCRLSAKEVSNKKKPGYYCDGAGLYLQISDSGSKSWIFRYTLNGKNRHMGLGPVHTVSLADARTAAVQCRQLLLRK
MDPITARDAEHAQQSLEAARSMTFSECAALYIKAHRSSWKNTKHADQWTNTIKTYCGPVIGPLSVQDVDTKLIMKVLDPI
WEQKPETASRLRGRIESVLDWATVRGYREGDNPARWRGYLSHALPSLKKKLRVKHHPALQFSQMAEFMGLLRAEEGIAAR
ALEFLILTAARTSEVIGARWEELDLKASIWTIPGTRMKADDPHRVPLSGRALEIILNLEKIKQSDYVFPGQKIEKPLSNN
AMLKVLERMGRNDITVHGFRSSFRDWASECTNFPRDVCEMALAHTISNKAEAAYRRGDLFEKRRVLMEEWAGYCYDGSAI
MSR
>Mature_403_residues
MRRQTCRLSAKEVSNKKKPGYYCDGAGLYLQISDSGSKSWIFRYTLNGKNRHMGLGPVHTVSLADARTAAVQCRQLLLRK
MDPITARDAEHAQQSLEAARSMTFSECAALYIKAHRSSWKNTKHADQWTNTIKTYCGPVIGPLSVQDVDTKLIMKVLDPI
WEQKPETASRLRGRIESVLDWATVRGYREGDNPARWRGYLSHALPSLKKKLRVKHHPALQFSQMAEFMGLLRAEEGIAAR
ALEFLILTAARTSEVIGARWEELDLKASIWTIPGTRMKADDPHRVPLSGRALEIILNLEKIKQSDYVFPGQKIEKPLSNN
AMLKVLERMGRNDITVHGFRSSFRDWASECTNFPRDVCEMALAHTISNKAEAAYRRGDLFEKRRVLMEEWAGYCYDGSAI
MSR

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=414, Percent_Identity=31.8840579710145, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI145693166, Length=368, Percent_Identity=31.25, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1788690, Length=386, Percent_Identity=28.7564766839378, Blast_Score=143, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45772; Mature: 45772

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQTCRLSAKEVSNKKKPGYYCDGAGLYLQISDSGSKSWIFRYTLNGKNRHMGLGPVHT
CCCCHHCCCHHHHCCCCCCCEEECCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCEE
VSLADARTAAVQCRQLLLRKMDPITARDAEHAQQSLEAARSMTFSECAALYIKAHRSSWK
EEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
NTKHADQWTNTIKTYCGPVIGPLSVQDVDTKLIMKVLDPIWEQKPETASRLRGRIESVLD
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WATVRGYREGDNPARWRGYLSHALPSLKKKLRVKHHPALQFSQMAEFMGLLRAEEGIAAR
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHH
ALEFLILTAARTSEVIGARWEELDLKASIWTIPGTRMKADDPHRVPLSGRALEIILNLEK
HHHHHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHEEHHHHH
IKQSDYVFPGQKIEKPLSNNAMLKVLERMGRNDITVHGFRSSFRDWASECTNFPRDVCEM
HCCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHH
ALAHTISNKAEAAYRRGDLFEKRRVLMEEWAGYCYDGSAIMSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHCC
>Mature Secondary Structure
MRRQTCRLSAKEVSNKKKPGYYCDGAGLYLQISDSGSKSWIFRYTLNGKNRHMGLGPVHT
CCCCHHCCCHHHHCCCCCCCEEECCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCEE
VSLADARTAAVQCRQLLLRKMDPITARDAEHAQQSLEAARSMTFSECAALYIKAHRSSWK
EEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
NTKHADQWTNTIKTYCGPVIGPLSVQDVDTKLIMKVLDPIWEQKPETASRLRGRIESVLD
CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
WATVRGYREGDNPARWRGYLSHALPSLKKKLRVKHHPALQFSQMAEFMGLLRAEEGIAAR
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHH
ALEFLILTAARTSEVIGARWEELDLKASIWTIPGTRMKADDPHRVPLSGRALEIILNLEK
HHHHHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHEEHHHHH
IKQSDYVFPGQKIEKPLSNNAMLKVLERMGRNDITVHGFRSSFRDWASECTNFPRDVCEM
HCCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHH
ALAHTISNKAEAAYRRGDLFEKRRVLMEEWAGYCYDGSAIMSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]