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The map label for this gene is mepA [H]

Identifier: 82702049

GI number: 82702049

Start: 1045267

End: 1046967

Strand: Reverse

Name: mepA [H]

Synonym: Nmul_A0920

Alternate gene names: 82702049

Gene position: 1046967-1045267 (Counterclockwise)

Preceding gene: 82702052

Following gene: 82702044

Centisome position: 32.88

GC content: 59.44

Gene sequence:

>1701_bases
ATGCAGCCAAAATTGTTCTCATCCACCATGTCCCGCCGCACATTCCTGAAAGCTGCGGCGGCGACCACCGCCGCCATCGG
CGCTTCTGCCCTGCCCTTCGGAGCCCAGGCACAAGGGAAAGCAAAGTATCGGCGTTTGAACGTTCTGAACCCTGGGGCAA
AGCGCGCCATCGAAAGCTACAAGAGGGCTATCGCCAGGATGCTCAAGCTCCCGCCGGAAGACCCTCGCAACTGGTATCGC
ATCGCGCTCACTCACACGATGGATTGCCCGCACGGCAACTGGTGGTTTCTGGTCTGGCACCGCGGCTATATCGGCTGGTT
CGAGCAGATTTGCCGTGAGCTCAGCGGCGACCCAGGGTTTGCTCTTCCCTACTGGGATTGGACGGAGAATACGGACCCCG
ACAGTCCCTTTCAGGCACGCGTGCCCGCCGTCATGTTCGAGGATGTGCTCACCCCCGCTCATCCGGCCTATATTGCAAAC
TCGCGCGAATTTCAGAACCGCTTTCGCGGGGTAATCGCCAGGGCGGATTACTGGAAGCGTTTTTGCGGGCCGAATGGTGA
ATTCGATGATGAGACGCAGTATGGTCAGCTCCTCGCCCGGGGAATCCGCTCCCCCGAGGATCTGTGGTTCGATATGCTAA
ACGATCCGAGAGGCCGCTTTTTTTTCGATCTGAAACAGGCGCGCGGCACGACCCGGGAAAAGCCGGAGCTCGATGGAAAA
ACAACGAAGGCCGTCTCCCTGCAAACATTGCTGGACGCGCTGGCCCCTCGCGATTTCCTCACGTTTGCCAGCCCAAAGAC
CCTTGGTCACAGTGCCCTCACCGGATTTGGCGTGCTGGAAGGACAGCCGCACAACAGGGTGCACAACTGCGTCGGCGGCA
TCTTTACCGACCCCAATGGCAACACCACCAACAACGGCGGCTTCATGCAGGCCAATCTATCGCCTGTCGACCCGCTTTTT
TTTCTGCACCATGCGAATATCGATCGGCTTTGGGATGTATGGACCCGGAAGCAGTTGGCGAGGGGATATCCTGCCTTGCC
CGAAGGCGCGGATTTCGACGCCTGGTCGAGGGAACCGTTTCTTTTCTTTGTCGATGCAAAGGGAAAGCCGGCGAAGAAAA
GAACCGCCGGGGACTACGCGGCTATCGGGGATTTCAATTACGATTATGAGCCCGGCTCCGGGGAGGAAGTGGTGGCGCCT
CCCATGTTCGCCTCACTGCTGGGCGCAGCGGTACCCTCCGAGAGCACCCGGGCCCAGATCACCCGTTCCGTGGTGAGCGG
GGAGCAGGCGGCAAGCGCGGTCGTGACACTTCCGTCTCCGCTGCTTGGCTTGCGCGCACAGGCGGAAACGCCGCGATTGT
ATGCAAAGATCACCCTGGCGCTGCCGCCGCTGGCGCACCATCATGATTTTGCCGTGATGGTGGATGACGGGAACAGTCGA
ACGGACCCCTCCAGTCCTCACTACGTCGGTACGCTCTCGATGTTCGGTCATCACACCATACAGGCTCCGGTTACCTTTAC
CGTGCCTTTATCGGGCACGATCGAGGCAATGCGGCAGAACGCGCAGCTTACAGACAGCGGGGCGTTGAATATCCGGATTG
TTTCGGAGCGAATGGTAAAACCGGGAGTACCGATGGCAAGACATGCCCCTGGCACGGAACCGAAAGCGGAGGTACTTTCC
ATTGTTGTGGAGGCCCATTGA

Upstream 100 bases:

>100_bases
AATTGCGTGCCCCATGCCCGCCGTCCCGTCAAGCTTTATCCATCCGACTTTATCCGTTCAGCTTTATCCAGAATCGATAA
CCATAAACAGGGTTTAATCC

Downstream 100 bases:

>100_bases
CTGCCGCGAAATGCAGATGGCAGCTACGCTTCGCCACGGTAATTGCCGTTCTGATATTCTCGTCCATACTGGGATTCTCG
TCCATACTGGGAAATGGCGC

Product: tyrosinase

Products: NA

Alternate protein names: Monophenol monooxygenase [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MQPKLFSSTMSRRTFLKAAAATTAAIGASALPFGAQAQGKAKYRRLNVLNPGAKRAIESYKRAIARMLKLPPEDPRNWYR
IALTHTMDCPHGNWWFLVWHRGYIGWFEQICRELSGDPGFALPYWDWTENTDPDSPFQARVPAVMFEDVLTPAHPAYIAN
SREFQNRFRGVIARADYWKRFCGPNGEFDDETQYGQLLARGIRSPEDLWFDMLNDPRGRFFFDLKQARGTTREKPELDGK
TTKAVSLQTLLDALAPRDFLTFASPKTLGHSALTGFGVLEGQPHNRVHNCVGGIFTDPNGNTTNNGGFMQANLSPVDPLF
FLHHANIDRLWDVWTRKQLARGYPALPEGADFDAWSREPFLFFVDAKGKPAKKRTAGDYAAIGDFNYDYEPGSGEEVVAP
PMFASLLGAAVPSESTRAQITRSVVSGEQAASAVVTLPSPLLGLRAQAETPRLYAKITLALPPLAHHHDFAVMVDDGNSR
TDPSSPHYVGTLSMFGHHTIQAPVTFTVPLSGTIEAMRQNAQLTDSGALNIRIVSERMVKPGVPMARHAPGTEPKAEVLS
IVVEAH

Sequences:

>Translated_566_residues
MQPKLFSSTMSRRTFLKAAAATTAAIGASALPFGAQAQGKAKYRRLNVLNPGAKRAIESYKRAIARMLKLPPEDPRNWYR
IALTHTMDCPHGNWWFLVWHRGYIGWFEQICRELSGDPGFALPYWDWTENTDPDSPFQARVPAVMFEDVLTPAHPAYIAN
SREFQNRFRGVIARADYWKRFCGPNGEFDDETQYGQLLARGIRSPEDLWFDMLNDPRGRFFFDLKQARGTTREKPELDGK
TTKAVSLQTLLDALAPRDFLTFASPKTLGHSALTGFGVLEGQPHNRVHNCVGGIFTDPNGNTTNNGGFMQANLSPVDPLF
FLHHANIDRLWDVWTRKQLARGYPALPEGADFDAWSREPFLFFVDAKGKPAKKRTAGDYAAIGDFNYDYEPGSGEEVVAP
PMFASLLGAAVPSESTRAQITRSVVSGEQAASAVVTLPSPLLGLRAQAETPRLYAKITLALPPLAHHHDFAVMVDDGNSR
TDPSSPHYVGTLSMFGHHTIQAPVTFTVPLSGTIEAMRQNAQLTDSGALNIRIVSERMVKPGVPMARHAPGTEPKAEVLS
IVVEAH
>Mature_566_residues
MQPKLFSSTMSRRTFLKAAAATTAAIGASALPFGAQAQGKAKYRRLNVLNPGAKRAIESYKRAIARMLKLPPEDPRNWYR
IALTHTMDCPHGNWWFLVWHRGYIGWFEQICRELSGDPGFALPYWDWTENTDPDSPFQARVPAVMFEDVLTPAHPAYIAN
SREFQNRFRGVIARADYWKRFCGPNGEFDDETQYGQLLARGIRSPEDLWFDMLNDPRGRFFFDLKQARGTTREKPELDGK
TTKAVSLQTLLDALAPRDFLTFASPKTLGHSALTGFGVLEGQPHNRVHNCVGGIFTDPNGNTTNNGGFMQANLSPVDPLF
FLHHANIDRLWDVWTRKQLARGYPALPEGADFDAWSREPFLFFVDAKGKPAKKRTAGDYAAIGDFNYDYEPGSGEEVVAP
PMFASLLGAAVPSESTRAQITRSVVSGEQAASAVVTLPSPLLGLRAQAETPRLYAKITLALPPLAHHHDFAVMVDDGNSR
TDPSSPHYVGTLSMFGHHTIQAPVTFTVPLSGTIEAMRQNAQLTDSGALNIRIVSERMVKPGVPMARHAPGTEPKAEVLS
IVVEAH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tyrosinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008922
- InterPro:   IPR002227 [H]

Pfam domain/function: PF00264 Tyrosinase [H]

EC number: =1.14.18.1 [H]

Molecular weight: Translated: 62630; Mature: 62630

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS00498 TYROSINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPKLFSSTMSRRTFLKAAAATTAAIGASALPFGAQAQGKAKYRRLNVLNPGAKRAIESY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHH
KRAIARMLKLPPEDPRNWYRIALTHTMDCPHGNWWFLVWHRGYIGWFEQICRELSGDPGF
HHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCE
ALPYWDWTENTDPDSPFQARVPAVMFEDVLTPAHPAYIANSREFQNRFRGVIARADYWKR
ECCCCCCCCCCCCCCCHHHCCCHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHH
FCGPNGEFDDETQYGQLLARGIRSPEDLWFDMLNDPRGRFFFDLKQARGTTREKPELDGK
HCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCC
TTKAVSLQTLLDALAPRDFLTFASPKTLGHSALTGFGVLEGQPHNRVHNCVGGIFTDPNG
CCHHHHHHHHHHHHCCCHHEECCCCCCCCCHHHCCCEEECCCCCHHHHHHHCCEEECCCC
NTTNNGGFMQANLSPVDPLFFLHHANIDRLWDVWTRKQLARGYPALPEGADFDAWSREPF
CCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCE
LFFVDAKGKPAKKRTAGDYAAIGDFNYDYEPGSGEEVVAPPMFASLLGAAVPSESTRAQI
EEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCHHHHHH
TRSVVSGEQAASAVVTLPSPLLGLRAQAETPRLYAKITLALPPLAHHHDFAVMVDDGNSR
HHHHHCCHHHCCEEEECCCCHHCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCC
TDPSSPHYVGTLSMFGHHTIQAPVTFTVPLSGTIEAMRQNAQLTDSGALNIRIVSERMVK
CCCCCCCEEEEHHHHCCEEEECCEEEEEECCHHHHHHHCCCCCCCCCCEEEEEECHHHCC
PGVPMARHAPGTEPKAEVLSIVVEAH
CCCCCCCCCCCCCCHHHHHEEEEECC
>Mature Secondary Structure
MQPKLFSSTMSRRTFLKAAAATTAAIGASALPFGAQAQGKAKYRRLNVLNPGAKRAIESY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEECCCCHHHHHHHHH
KRAIARMLKLPPEDPRNWYRIALTHTMDCPHGNWWFLVWHRGYIGWFEQICRELSGDPGF
HHHHHHHHCCCCCCCCCEEEEEEEEEECCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCE
ALPYWDWTENTDPDSPFQARVPAVMFEDVLTPAHPAYIANSREFQNRFRGVIARADYWKR
ECCCCCCCCCCCCCCCHHHCCCHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHH
FCGPNGEFDDETQYGQLLARGIRSPEDLWFDMLNDPRGRFFFDLKQARGTTREKPELDGK
HCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCCCCC
TTKAVSLQTLLDALAPRDFLTFASPKTLGHSALTGFGVLEGQPHNRVHNCVGGIFTDPNG
CCHHHHHHHHHHHHCCCHHEECCCCCCCCCHHHCCCEEECCCCCHHHHHHHCCEEECCCC
NTTNNGGFMQANLSPVDPLFFLHHANIDRLWDVWTRKQLARGYPALPEGADFDAWSREPF
CCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCE
LFFVDAKGKPAKKRTAGDYAAIGDFNYDYEPGSGEEVVAPPMFASLLGAAVPSESTRAQI
EEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEECCHHHHHHHHHCCCCCHHHHHH
TRSVVSGEQAASAVVTLPSPLLGLRAQAETPRLYAKITLALPPLAHHHDFAVMVDDGNSR
HHHHHCCHHHCCEEEECCCCHHCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCCCC
TDPSSPHYVGTLSMFGHHTIQAPVTFTVPLSGTIEAMRQNAQLTDSGALNIRIVSERMVK
CCCCCCCEEEEHHHHCCEEEECCEEEEEECCHHHHHHHCCCCCCCCCCEEEEEECHHHCC
PGVPMARHAPGTEPKAEVLSIVVEAH
CCCCCCCCCCCCCCHHHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8366027 [H]