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The map label for this gene is polX [H]

Identifier: 82702030

GI number: 82702030

Start: 1025223

End: 1027019

Strand: Reverse

Name: polX [H]

Synonym: Nmul_A0901

Alternate gene names: 82702030

Gene position: 1027019-1025223 (Counterclockwise)

Preceding gene: 82702037

Following gene: 82702029

Centisome position: 32.25

GC content: 58.32

Gene sequence:

>1797_bases
ATGCCCAGCCATAATGCCGATATCGCCGCTGTCTTCGAAGAGATTGCCAATCTGCTCGAGATCGAAGGCGCAAACCCTTT
TCGGATACGCGCCTACCGTAACGCAGTCCAGGCAATAGGCGCCCTTTCCACCGAAGCGTACGTGCTGCTCGAAAACAAGG
AAGACCTGACGGAGCTTCCCGGCATAGGGCGCGATCTTGCAGGCAAGATCGAAGAAATTATTGCCACCGGCCATTGCGCC
TTGCTGGATCGGCTGCAAACCGAGCTTCCCCCCGCGGTTACAGAGCTTCTGAAAGTGCCCGGCCTCGGGCCGAAGCGGGT
CCGGCATCTTTATCACGACCTGGATGTCCAGACTGTCGAGCAGCTCTACGGCGCGGCGCGTGAGGGACGCATTCGTGCAC
TATCTGGTTTTGGCGAGAAAACCGAGCTCAACATCCTCCAGGCGATCGAGGCGCATACCGATCAGAAAGGGCGTTTCAAG
CTGGCGGTGGCGGCGCAATACGCCGAGCCGCTGCGCGCGTTTCTGGCAGACGTTCCCGGAGTCAAGGAAGCAATCGTCGC
CGGCAGCTACCGGCGCATGCGCGAAACGGTTGGGGATCTCGATATCGTTGTCACAGCCGCATCGGGCAGTCCTGTCATGG
AGCGCTTCACCGGGTACGAGGAGGTTGCAGAAATACTTGCTGCCGGAAGCACTCGCGCCAGCGTGGTCCTGAAATGCGGC
TTGCAGGTGGACCTGCGCGTGGTTGCGGACGAAAGCTACGGCGCTGCCCTGCACTATTTTACCGGATCAAAAGCCCATAA
TGTTGCGGTACGGTATATCGCCCAGAAAAAAGGGTTGAAAGTCAACGAATACGGCGTGTTCCGGGGTAAAAACCGCATCG
CGGGCGAGACCGAGGAATCGGTCTATCGTGCCGCCGGACTATCCTTTATTCCACCCGAGTTGCGCGAGAACAGGGGTGAA
ATAGACGTGGCACGAACCCGGAAATTGCCACGCCTAGTCGAGCTGTGCGACTTGCGGGGGGATCTGCATACTCACACAAA
AGCTACGGACGGTCATAACACCTTGCGCGAAATGGCACTGGCCGGCAAATCGCATGGCCTGGAATACATTGCCGTCACGG
ATCATTCACGCGGACTGAGAGTCACCCGCGGCCTCGATCCTCTCCGGCTGAAGCGCCAGTGCGATGAGATCGACGCGCTG
AATGAAGAACTGGAAGGAATTACCCTGCTCAAGGGAATCGAGGTGGACATTCTGGAGGATGGCACCCTGGATCTGCCGGA
TCACGTTCTGGCGCAACTCGATCTGGTCGTAGGGGCAGTCCACAGCAAGTTCGAGCTTCCGCGGGCGAGGCAGACCGAGC
GGATACTGCGCGCAATGGAACATCCCCATTTCACCGTTCTTGCGCATCCCAACGGTCGCCTCATCCCGCAGCGCCCGCCT
TATGATATCGATATGCCCCGCATTATCCGTGAAGCAGGACGCCGCGGATGCTTCCTCGAACTCAATGCCCAGCCCGAGCG
GCTGGATTTGTTCGATATCTACTGCCAGATGGCCAAGGAGGAAGGGGTGCTGGTCAGCATCAATTCCGACGCCCACAGCA
CTTTTGATTTCGCGAACCTGCGCTTTGGTATCGGTCAGGCAAGGCGGGGCTGGCTGGAAAAACAGGATGTGCTCAACACC
CGCTCTCTCGAGGAATTACGAATACTCATTGCCCGCACGATGCAGCGCCCCAACACCTGCGGCCCGTACAAACGGCAAAC
CAAGCCTCAAATCCGGTCAGGTAAAAATGTCCGGTAA

Upstream 100 bases:

>100_bases
TCTCCATGAATATACTAAACTGACCTTGTGAATCCTCGACCAGCAACTTTCCCCGCAAAATCAGCAAAGTGCTTGTGGAC
GGAAGCAAACGGGAATGCGC

Downstream 100 bases:

>100_bases
AAAATTCACCTATACTGAAAATAAACACGTGATCGGGGGCAGCATGTATTTTGAAAATCGCGCGGCAGCAGCCAGGAAGC
TTGCGGAAGCGCTTTCAGAA

Product: PHP-like protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MPSHNADIAAVFEEIANLLEIEGANPFRIRAYRNAVQAIGALSTEAYVLLENKEDLTELPGIGRDLAGKIEEIIATGHCA
LLDRLQTELPPAVTELLKVPGLGPKRVRHLYHDLDVQTVEQLYGAAREGRIRALSGFGEKTELNILQAIEAHTDQKGRFK
LAVAAQYAEPLRAFLADVPGVKEAIVAGSYRRMRETVGDLDIVVTAASGSPVMERFTGYEEVAEILAAGSTRASVVLKCG
LQVDLRVVADESYGAALHYFTGSKAHNVAVRYIAQKKGLKVNEYGVFRGKNRIAGETEESVYRAAGLSFIPPELRENRGE
IDVARTRKLPRLVELCDLRGDLHTHTKATDGHNTLREMALAGKSHGLEYIAVTDHSRGLRVTRGLDPLRLKRQCDEIDAL
NEELEGITLLKGIEVDILEDGTLDLPDHVLAQLDLVVGAVHSKFELPRARQTERILRAMEHPHFTVLAHPNGRLIPQRPP
YDIDMPRIIREAGRRGCFLELNAQPERLDLFDIYCQMAKEEGVLVSINSDAHSTFDFANLRFGIGQARRGWLEKQDVLNT
RSLEELRILIARTMQRPNTCGPYKRQTKPQIRSGKNVR

Sequences:

>Translated_598_residues
MPSHNADIAAVFEEIANLLEIEGANPFRIRAYRNAVQAIGALSTEAYVLLENKEDLTELPGIGRDLAGKIEEIIATGHCA
LLDRLQTELPPAVTELLKVPGLGPKRVRHLYHDLDVQTVEQLYGAAREGRIRALSGFGEKTELNILQAIEAHTDQKGRFK
LAVAAQYAEPLRAFLADVPGVKEAIVAGSYRRMRETVGDLDIVVTAASGSPVMERFTGYEEVAEILAAGSTRASVVLKCG
LQVDLRVVADESYGAALHYFTGSKAHNVAVRYIAQKKGLKVNEYGVFRGKNRIAGETEESVYRAAGLSFIPPELRENRGE
IDVARTRKLPRLVELCDLRGDLHTHTKATDGHNTLREMALAGKSHGLEYIAVTDHSRGLRVTRGLDPLRLKRQCDEIDAL
NEELEGITLLKGIEVDILEDGTLDLPDHVLAQLDLVVGAVHSKFELPRARQTERILRAMEHPHFTVLAHPNGRLIPQRPP
YDIDMPRIIREAGRRGCFLELNAQPERLDLFDIYCQMAKEEGVLVSINSDAHSTFDFANLRFGIGQARRGWLEKQDVLNT
RSLEELRILIARTMQRPNTCGPYKRQTKPQIRSGKNVR
>Mature_597_residues
PSHNADIAAVFEEIANLLEIEGANPFRIRAYRNAVQAIGALSTEAYVLLENKEDLTELPGIGRDLAGKIEEIIATGHCAL
LDRLQTELPPAVTELLKVPGLGPKRVRHLYHDLDVQTVEQLYGAAREGRIRALSGFGEKTELNILQAIEAHTDQKGRFKL
AVAAQYAEPLRAFLADVPGVKEAIVAGSYRRMRETVGDLDIVVTAASGSPVMERFTGYEEVAEILAAGSTRASVVLKCGL
QVDLRVVADESYGAALHYFTGSKAHNVAVRYIAQKKGLKVNEYGVFRGKNRIAGETEESVYRAAGLSFIPPELRENRGEI
DVARTRKLPRLVELCDLRGDLHTHTKATDGHNTLREMALAGKSHGLEYIAVTDHSRGLRVTRGLDPLRLKRQCDEIDALN
EELEGITLLKGIEVDILEDGTLDLPDHVLAQLDLVVGAVHSKFELPRARQTERILRAMEHPHFTVLAHPNGRLIPQRPPY
DIDMPRIIREAGRRGCFLELNAQPERLDLFDIYCQMAKEEGVLVSINSDAHSTFDFANLRFGIGQARRGWLEKQDVLNTR
SLEELRILIARTMQRPNTCGPYKRQTKPQIRSGKNVR

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1796

COG function: function code L; DNA polymerase IV (family X)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 66525; Mature: 66394

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00063 ALDOKETO_REDUCTASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSHNADIAAVFEEIANLLEIEGANPFRIRAYRNAVQAIGALSTEAYVLLENKEDLTELP
CCCCCCHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHCCCCCEEEEEECCCHHHHCC
GIGRDLAGKIEEIIATGHCALLDRLQTELPPAVTELLKVPGLGPKRVRHLYHDLDVQTVE
CCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHH
QLYGAAREGRIRALSGFGEKTELNILQAIEAHTDQKGRFKLAVAAQYAEPLRAFLADVPG
HHHCCHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCC
VKEAIVAGSYRRMRETVGDLDIVVTAASGSPVMERFTGYEEVAEILAAGSTRASVVLKCG
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHCCHHHHHHHHHCCCCCEEEEEEEC
LQVDLRVVADESYGAALHYFTGSKAHNVAVRYIAQKKGLKVNEYGVFRGKNRIAGETEES
CEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCHHHH
VYRAAGLSFIPPELRENRGEIDVARTRKLPRLVELCDLRGDLHTHTKATDGHNTLREMAL
HHHHCCCCCCCHHHHCCCCCEEHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
AGKSHGLEYIAVTDHSRGLRVTRGLDPLRLKRQCDEIDALNEELEGITLLKGIEVDILED
HHHCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECC
GTLDLPDHVLAQLDLVVGAVHSKFELPRARQTERILRAMEHPHFTVLAHPNGRLIPQRPP
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
YDIDMPRIIREAGRRGCFLELNAQPERLDLFDIYCQMAKEEGVLVSINSDAHSTFDFANL
CCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHH
RFGIGQARRGWLEKQDVLNTRSLEELRILIARTMQRPNTCGPYKRQTKPQIRSGKNVR
EECCCHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
PSHNADIAAVFEEIANLLEIEGANPFRIRAYRNAVQAIGALSTEAYVLLENKEDLTELP
CCCCCHHHHHHHHHHHHHEECCCCCEEHHHHHHHHHHHHCCCCCEEEEEECCCHHHHCC
GIGRDLAGKIEEIIATGHCALLDRLQTELPPAVTELLKVPGLGPKRVRHLYHDLDVQTVE
CCCHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCHHHHH
QLYGAAREGRIRALSGFGEKTELNILQAIEAHTDQKGRFKLAVAAQYAEPLRAFLADVPG
HHHCCHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCC
VKEAIVAGSYRRMRETVGDLDIVVTAASGSPVMERFTGYEEVAEILAAGSTRASVVLKCG
HHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHCCHHHHHHHHHCCCCCEEEEEEEC
LQVDLRVVADESYGAALHYFTGSKAHNVAVRYIAQKKGLKVNEYGVFRGKNRIAGETEES
CEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEECCCEEECCCCCCCCHHHH
VYRAAGLSFIPPELRENRGEIDVARTRKLPRLVELCDLRGDLHTHTKATDGHNTLREMAL
HHHHCCCCCCCHHHHCCCCCEEHHHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
AGKSHGLEYIAVTDHSRGLRVTRGLDPLRLKRQCDEIDALNEELEGITLLKGIEVDILED
HHHCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECC
GTLDLPDHVLAQLDLVVGAVHSKFELPRARQTERILRAMEHPHFTVLAHPNGRLIPQRPP
CCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
YDIDMPRIIREAGRRGCFLELNAQPERLDLFDIYCQMAKEEGVLVSINSDAHSTFDFANL
CCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHH
RFGIGQARRGWLEKQDVLNTRSLEELRILIARTMQRPNTCGPYKRQTKPQIRSGKNVR
EECCCHHHHCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]