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The map label for this gene is murA

Identifier: 82702015

GI number: 82702015

Start: 1007178

End: 1008428

Strand: Direct

Name: murA

Synonym: Nmul_A0886

Alternate gene names: 82702015

Gene position: 1007178-1008428 (Clockwise)

Preceding gene: 82702006

Following gene: 82702017

Centisome position: 31.63

GC content: 55.8

Gene sequence:

>1251_bases
ATGCAAAAACTGATCATTCAGGGAGGGGTGCGGCTTTCCGGCGATGTAACCATTTCCGGAGCCAAGAACGCGGCACTGCC
TATCCTGTGCGCCTCCCTGCTTACCGGGGAAACCCTCGTCGTCGAAAACGTTCCGCATCTGAATGATATAACCACCATGC
TGGACCTGCTCCAGCAGATGGGGGTTCGAACCAATGTCGACAGCAATCGTACGACTGAACTCACTGCGGCATATCTTTCC
AATCTCGTTGCGCCGTACGAAATGGTGAAAACCATGCGGGCTGCAATTCTGGTGCTGGGTCCCATGCTTGCGCGGGCGGG
AGCCGCAAAAGTGTCGCTGCCCGGCGGGTGCGCCATTGGCCTGCGTCCCGTTGATCAGCATATAAAAGGATTGCAGGCAA
TGGGTGCGGAGATCGAGATCGAGCACGGTTATATTCATGCAAAGGCGAAACGCCTTAACGGCGCGCATATCGTGATGGAT
ATCGTCACGGTCACCGGCACTGAAAACCTGATGATGGCGGCCACGCTGGCGGAAGGGACGACTGTGCTGGAAAATGCGGC
GCGGGAACCGGAAGTGATGGATCTCGCGAACTGCCTTATCGCCATGGGAGCCAGAATTCAGGGAGTCGGAACGGACATCA
TCACCATTGAAGGCGTGGAAAGCCTGCATGGTACCCACTATTGCGTCATGCCCGATCGTATCGAAAGCGGCACGTTCCTG
GTAGCAGCCGCAGCCAGCGGTGGCGAAATATATCTCAGGCAGACGCGCACCGATACGATGGATGCGGTGCTCGACAAGCT
GATGGAAGCGGGGGCTGCCATCGAGTCAGGTGAAGACTGGATACACCTGAAAATGAATAATCCGCCGAAATCGGTAAACC
TGCGGACGGCCCCTTATCCTGCCTTTCCTACCGATATGCAGGCGCAATTCATGGTATTGAATACCATCGCTACCGGAACC
GCAATCATTACCGAAACCATATTCGAGAATCGCTTCATGCACGTGCAGGAATTGGAGCGTATGAATGCTGACATCAAAGT
CGAAGGCAATACCGCAGTGGTATGCGGCGTGGCCGGCCTCGATGGAGCCAACGTCATGGCAACCGATCTGCGTGCTTCGG
CCTGTCTGGTTCTGGCCGGGCTGATCGCCCGGGGTGAAACGATCGTTGATCGTATTTATCATCTTGACCGTGGTTATGAA
CGGATCGAAGAGAAGCTGTCGGCGCTGGGTGCACGAATCAGGCGCAGTTGA

Upstream 100 bases:

>100_bases
TCTCCTTTGGTTGATAATACGTTGACATAATAAGCCGAAATTTGAAACTACGGGTATCGTGTTTGCGATATGATGACGGG
AACCTCAGCACATTTCAACC

Downstream 100 bases:

>100_bases
GGTATTGCAACCAAACGAATTATTTGAGCTATGCATCATGCTTAGCTCAATCCGGCCGAGGTCCTCACTCCCCTCTCTCA
CTTGCGGAAGAGAGGTCGGG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MQKLIIQGGVRLSGDVTISGAKNAALPILCASLLTGETLVVENVPHLNDITTMLDLLQQMGVRTNVDSNRTTELTAAYLS
NLVAPYEMVKTMRAAILVLGPMLARAGAAKVSLPGGCAIGLRPVDQHIKGLQAMGAEIEIEHGYIHAKAKRLNGAHIVMD
IVTVTGTENLMMAATLAEGTTVLENAAREPEVMDLANCLIAMGARIQGVGTDIITIEGVESLHGTHYCVMPDRIESGTFL
VAAAASGGEIYLRQTRTDTMDAVLDKLMEAGAAIESGEDWIHLKMNNPPKSVNLRTAPYPAFPTDMQAQFMVLNTIATGT
AIITETIFENRFMHVQELERMNADIKVEGNTAVVCGVAGLDGANVMATDLRASACLVLAGLIARGETIVDRIYHLDRGYE
RIEEKLSALGARIRRS

Sequences:

>Translated_416_residues
MQKLIIQGGVRLSGDVTISGAKNAALPILCASLLTGETLVVENVPHLNDITTMLDLLQQMGVRTNVDSNRTTELTAAYLS
NLVAPYEMVKTMRAAILVLGPMLARAGAAKVSLPGGCAIGLRPVDQHIKGLQAMGAEIEIEHGYIHAKAKRLNGAHIVMD
IVTVTGTENLMMAATLAEGTTVLENAAREPEVMDLANCLIAMGARIQGVGTDIITIEGVESLHGTHYCVMPDRIESGTFL
VAAAASGGEIYLRQTRTDTMDAVLDKLMEAGAAIESGEDWIHLKMNNPPKSVNLRTAPYPAFPTDMQAQFMVLNTIATGT
AIITETIFENRFMHVQELERMNADIKVEGNTAVVCGVAGLDGANVMATDLRASACLVLAGLIARGETIVDRIYHLDRGYE
RIEEKLSALGARIRRS
>Mature_416_residues
MQKLIIQGGVRLSGDVTISGAKNAALPILCASLLTGETLVVENVPHLNDITTMLDLLQQMGVRTNVDSNRTTELTAAYLS
NLVAPYEMVKTMRAAILVLGPMLARAGAAKVSLPGGCAIGLRPVDQHIKGLQAMGAEIEIEHGYIHAKAKRLNGAHIVMD
IVTVTGTENLMMAATLAEGTTVLENAAREPEVMDLANCLIAMGARIQGVGTDIITIEGVESLHGTHYCVMPDRIESGTFL
VAAAASGGEIYLRQTRTDTMDAVLDKLMEAGAAIESGEDWIHLKMNNPPKSVNLRTAPYPAFPTDMQAQFMVLNTIATGT
AIITETIFENRFMHVQELERMNADIKVEGNTAVVCGVAGLDGANVMATDLRASACLVLAGLIARGETIVDRIYHLDRGYE
RIEEKLSALGARIRRS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=61.3908872901679, Blast_Score=501, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_NITMU (Q2YAN2)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411581.1
- ProteinModelPortal:   Q2YAN2
- SMR:   Q2YAN2
- STRING:   Q2YAN2
- GeneID:   3785928
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0886
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q2YAN2
- ProtClustDB:   PRK09369
- BioCyc:   NMUL323848:NMUL_A0886-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44543; Mature: 44543

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLIIQGGVRLSGDVTISGAKNAALPILCASLLTGETLVVENVPHLNDITTMLDLLQQM
CCEEEEECCEEEECCEEEECCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHC
GVRTNVDSNRTTELTAAYLSNLVAPYEMVKTMRAAILVLGPMLARAGAAKVSLPGGCAIG
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEC
LRPVDQHIKGLQAMGAEIEIEHGYIHAKAKRLNGAHIVMDIVTVTGTENLMMAATLAEGT
CCCHHHHHHHHHHCCCEEEEECCEEEEEEHHCCCCEEEEEEEEECCCCCEEEEEEHHCCH
TVLENAAREPEVMDLANCLIAMGARIQGVGTDIITIEGVESLHGTHYCVMPDRIESGTFL
HHHHHCCCCCHHHHHHHHHHHHCCEEEECCCEEEEECCHHHHCCCEEEEECCCCCCCCEE
VAAAASGGEIYLRQTRTDTMDAVLDKLMEAGAAIESGEDWIHLKMNNPPKSVNLRTAPYP
EEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEECCCCC
AFPTDMQAQFMVLNTIATGTAIITETIFENRFMHVQELERMNADIKVEGNTAVVCGVAGL
CCCCCCCCEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCEEEEEEECCC
DGANVMATDLRASACLVLAGLIARGETIVDRIYHLDRGYERIEEKLSALGARIRRS
CCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKLIIQGGVRLSGDVTISGAKNAALPILCASLLTGETLVVENVPHLNDITTMLDLLQQM
CCEEEEECCEEEECCEEEECCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHC
GVRTNVDSNRTTELTAAYLSNLVAPYEMVKTMRAAILVLGPMLARAGAAKVSLPGGCAIG
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEEC
LRPVDQHIKGLQAMGAEIEIEHGYIHAKAKRLNGAHIVMDIVTVTGTENLMMAATLAEGT
CCCHHHHHHHHHHCCCEEEEECCEEEEEEHHCCCCEEEEEEEEECCCCCEEEEEEHHCCH
TVLENAAREPEVMDLANCLIAMGARIQGVGTDIITIEGVESLHGTHYCVMPDRIESGTFL
HHHHHCCCCCHHHHHHHHHHHHCCEEEECCCEEEEECCHHHHCCCEEEEECCCCCCCCEE
VAAAASGGEIYLRQTRTDTMDAVLDKLMEAGAAIESGEDWIHLKMNNPPKSVNLRTAPYP
EEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCEEECCCCC
AFPTDMQAQFMVLNTIATGTAIITETIFENRFMHVQELERMNADIKVEGNTAVVCGVAGL
CCCCCCCCEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCEEEEEEECCC
DGANVMATDLRASACLVLAGLIARGETIVDRIYHLDRGYERIEEKLSALGARIRRS
CCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA