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The map label for this gene is degP [H]

Identifier: 82701940

GI number: 82701940

Start: 924964

End: 926160

Strand: Direct

Name: degP [H]

Synonym: Nmul_A0807

Alternate gene names: 82701940

Gene position: 924964-926160 (Clockwise)

Preceding gene: 82701933

Following gene: 82701954

Centisome position: 29.05

GC content: 55.39

Gene sequence:

>1197_bases
ATGCACAAGCTCTGGCTAGTTTTCGCGCAAGCTACCACGATAGTTCTGGCAGCCCTGTTTGTCGTTTCGACTTTACGCCC
GGGTCTATTACCCTGGCAATCCGGAGATGGCGGTGTCGTAACCATAAAGGAAGCTCCGGTTGACAAGTCACACAAGGCAG
AGGTCGAGCCTGCCCCTGGGAGCTTCAGTAGCGCGGCGAAAAAGGCCATGCCCTCCGTGGTGAATGTATTCACCACCAAG
GAAATCAAGGCTGCCCCCCATCCCTTCATGGAGGATCCTTTCTTCCGGCGTTTCTTCGGAGATCGTTTCGAATCCCCTCA
GAGCCGCCGCGCCGCCAGCCTGGGATCCGGGGTGATCGTGAGTCCGCAGGGATATATCCTTACGAACCATCATGTCATTG
AAGCGGCGGATGAAATCGAGATTGCGCTGGCGGACGGGAGAAAAACGAAAGCGCGGGTCATCGGCTCCGATCCCGAAACC
GATCTTGCAGTGGTAAGAGTGGATATGGAAGGACTTCCGGCCATCACTTTCGGATACTCCGACAATGCCCTGGTCGGCGA
TATTGTCCTTGCGATCGGTAATCCTTTCGGTGTGGGCCAGACGGTAACGATGGGGATTATCAGCGCACTCGGACGAACCC
ATCTGGGTATCAACACCTTCGAAAATTTCATTCAGACCGATGCTGCCATCAATCCGGGAAATTCTGGCGGTGCACTGGTG
GATGCGTCGGGTAACCTCATCGGCATCAATACCGCCATAGTCTCCAGAACGGGAGGATCACTTGGGATAGGCTTTGCCAT
TACAGCAGGGGTAGCCAAGCAGATCATGGAGCAGATTATCCGGACAGGGGGCGTGACCCGTGGCTGGATCGGCGTGGAAG
TACAGGATATGACGCCGGAACTTGCGGAGTCGTTCAAGCGCTCGACTACCAGCGGGGCGTTGATTGCAGGTGTGCTCAAG
GGAGGACCTGCGGATCGTGCCGGAGTGAAGCCGGGTGACATTATTGTAGGAGTGGGAGGAAAAGAGGTAACGGATTCATC
CGGCATGCTCAATCTGGTAGCGGCATTACCTCCCGGAAACATGGCGACCATTACAGTCATGCGTAACCAGAACAAGAAGG
CAATCGAGATCAATGTTGGAAAACGTCCCAAGCCTCAGCCTCAGGAGCAGTTTCAGGAGCCCGAGGAGCTGGAATAA

Upstream 100 bases:

>100_bases
TTCGAGCTCATTCACTTGCATTGCTGCTCACCCGGTCGCATTCGTCTATGATTTAAAATCAATGCTGCTATTTTATCCCT
GATTCCACATCTCTCAATCT

Downstream 100 bases:

>100_bases
AAGCGGTTGTGGAAGAGGACGCAGTGACTATGGCATGAGATTGGAAATTATCTGAGCGAAAACGCGCTGTTTTTCCCCAG
GCAATAACTCAGCTCCTCTT

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MHKLWLVFAQATTIVLAALFVVSTLRPGLLPWQSGDGGVVTIKEAPVDKSHKAEVEPAPGSFSSAAKKAMPSVVNVFTTK
EIKAAPHPFMEDPFFRRFFGDRFESPQSRRAASLGSGVIVSPQGYILTNHHVIEAADEIEIALADGRKTKARVIGSDPET
DLAVVRVDMEGLPAITFGYSDNALVGDIVLAIGNPFGVGQTVTMGIISALGRTHLGINTFENFIQTDAAINPGNSGGALV
DASGNLIGINTAIVSRTGGSLGIGFAITAGVAKQIMEQIIRTGGVTRGWIGVEVQDMTPELAESFKRSTTSGALIAGVLK
GGPADRAGVKPGDIIVGVGGKEVTDSSGMLNLVAALPPGNMATITVMRNQNKKAIEINVGKRPKPQPQEQFQEPEELE

Sequences:

>Translated_398_residues
MHKLWLVFAQATTIVLAALFVVSTLRPGLLPWQSGDGGVVTIKEAPVDKSHKAEVEPAPGSFSSAAKKAMPSVVNVFTTK
EIKAAPHPFMEDPFFRRFFGDRFESPQSRRAASLGSGVIVSPQGYILTNHHVIEAADEIEIALADGRKTKARVIGSDPET
DLAVVRVDMEGLPAITFGYSDNALVGDIVLAIGNPFGVGQTVTMGIISALGRTHLGINTFENFIQTDAAINPGNSGGALV
DASGNLIGINTAIVSRTGGSLGIGFAITAGVAKQIMEQIIRTGGVTRGWIGVEVQDMTPELAESFKRSTTSGALIAGVLK
GGPADRAGVKPGDIIVGVGGKEVTDSSGMLNLVAALPPGNMATITVMRNQNKKAIEINVGKRPKPQPQEQFQEPEELE
>Mature_398_residues
MHKLWLVFAQATTIVLAALFVVSTLRPGLLPWQSGDGGVVTIKEAPVDKSHKAEVEPAPGSFSSAAKKAMPSVVNVFTTK
EIKAAPHPFMEDPFFRRFFGDRFESPQSRRAASLGSGVIVSPQGYILTNHHVIEAADEIEIALADGRKTKARVIGSDPET
DLAVVRVDMEGLPAITFGYSDNALVGDIVLAIGNPFGVGQTVTMGIISALGRTHLGINTFENFIQTDAAINPGNSGGALV
DASGNLIGINTAIVSRTGGSLGIGFAITAGVAKQIMEQIIRTGGVTRGWIGVEVQDMTPELAESFKRSTTSGALIAGVLK
GGPADRAGVKPGDIIVGVGGKEVTDSSGMLNLVAALPPGNMATITVMRNQNKKAIEINVGKRPKPQPQEQFQEPEELE

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=283, Percent_Identity=32.8621908127208, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI22129776, Length=255, Percent_Identity=34.5098039215686, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24308541, Length=278, Percent_Identity=31.294964028777, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI7019477, Length=285, Percent_Identity=34.3859649122807, Blast_Score=128, Evalue=8e-30,
Organism=Escherichia coli, GI1789629, Length=332, Percent_Identity=40.6626506024096, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1786356, Length=356, Percent_Identity=38.7640449438202, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI1789630, Length=342, Percent_Identity=37.4269005847953, Blast_Score=211, Evalue=5e-56,
Organism=Drosophila melanogaster, GI24646839, Length=264, Percent_Identity=33.7121212121212, Blast_Score=135, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41782; Mature: 41782

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKLWLVFAQATTIVLAALFVVSTLRPGLLPWQSGDGGVVTIKEAPVDKSHKAEVEPAPG
CCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCC
SFSSAAKKAMPSVVNVFTTKEIKAAPHPFMEDPFFRRFFGDRFESPQSRRAASLGSGVIV
CHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCEEE
SPQGYILTNHHVIEAADEIEIALADGRKTKARVIGSDPETDLAVVRVDMEGLPAITFGYS
CCCCEEEECCEEEECCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCEEEECCC
DNALVGDIVLAIGNPFGVGQTVTMGIISALGRTHLGINTFENFIQTDAAINPGNSGGALV
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEE
DASGNLIGINTAIVSRTGGSLGIGFAITAGVAKQIMEQIIRTGGVTRGWIGVEVQDMTPE
ECCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEECEEEEEECCCCHH
LAESFKRSTTSGALIAGVLKGGPADRAGVKPGDIIVGVGGKEVTDSSGMLNLVAALPPGN
HHHHHHHCCCCCCEEEHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCC
MATITVMRNQNKKAIEINVGKRPKPQPQEQFQEPEELE
EEEEEEEECCCCEEEEEECCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure
MHKLWLVFAQATTIVLAALFVVSTLRPGLLPWQSGDGGVVTIKEAPVDKSHKAEVEPAPG
CCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCC
SFSSAAKKAMPSVVNVFTTKEIKAAPHPFMEDPFFRRFFGDRFESPQSRRAASLGSGVIV
CHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCEEE
SPQGYILTNHHVIEAADEIEIALADGRKTKARVIGSDPETDLAVVRVDMEGLPAITFGYS
CCCCEEEECCEEEECCCCEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCEEEECCC
DNALVGDIVLAIGNPFGVGQTVTMGIISALGRTHLGINTFENFIQTDAAINPGNSGGALV
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEE
DASGNLIGINTAIVSRTGGSLGIGFAITAGVAKQIMEQIIRTGGVTRGWIGVEVQDMTPE
ECCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHCCCEECEEEEEECCCCHH
LAESFKRSTTSGALIAGVLKGGPADRAGVKPGDIIVGVGGKEVTDSSGMLNLVAALPPGN
HHHHHHHCCCCCCEEEHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCC
MATITVMRNQNKKAIEINVGKRPKPQPQEQFQEPEELE
EEEEEEEECCCCEEEEEECCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]