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The map label for this gene is aroB

Identifier: 82701836

GI number: 82701836

Start: 808956

End: 810056

Strand: Direct

Name: aroB

Synonym: Nmul_A0703

Alternate gene names: 82701836

Gene position: 808956-810056 (Clockwise)

Preceding gene: 82701835

Following gene: 82701837

Centisome position: 25.4

GC content: 53.32

Gene sequence:

>1101_bases
ATGGAAACAGTCACTGTTAATCTTGTCTCCACGCCCGCTCAACGCGGTTATCCGATCCATATCGGTGCAAACATCCTGAC
TCAGCCCGAGCTCATCCTGGATTACCTGGACCAGAAGCGAGTGGCCATTGTCACAAATACTACAGTCGGGCCTTTATATC
TCGAAAAGTTTCGTGCGGATCTTTCAGTTCATGGGATGGTTTCGGTTCCAATCGTTCTTCCGGACGGTGAGGAATACAAG
AACTGGGAAACCCTCAATCTCATTTTCGATGCTCTCCTGACCCATCGCTGCGAACGCAATACCCCGCTCATCGCCCTTGG
CGGAGGAGTTGTGGGAGACCTGACCGGTTTCGCCGCCGCCACTTATTTACGGGGTGTGCCGTTCATTCAGGTACCCACCA
CACTTCTGGCGCAAGTCGATTCTTCAGTTGGCGGTAAGACCGGAATCAACCATCCGCTGGGTAAAAACATGATTGGAGCG
TTTTATCAACCCCAGGCGGTCGTGGCGGATACGTCCACACTCGATACGTTGCCCGATAGAGAACTGCGTGCCGGTATAGC
GGAGGTCATCAAATATGGCCTTATTCGCGATCCGGCATTCTTCGACTGGATTGAATCTCATATTGAACTCCTGTTGCGGC
GTGATAATTCGATTCTGACCGACGCAATAAAAAGGAGTTGCCAGCATAAGGCAGAAGTTGTGGAAGAAGACGAGCGCGAG
AGCGGCATGCGTGCCTTGCTGAACCTTGGACACACTTTTGGCCATGCAATCGAGAATGCAATGGGGTACGGCAACTGGCT
TCACGGGGAAGCAGTGGCTGCAGGAACGATGCTGGCAGCCGAGGTGTCACGACGTATGGGCATGATAGGCGAGGAGGATG
TGGATCGGGTCCGAAATCTCTATGTGAAGACCGGGCTGCCGGTGATTGCCCCGAATCTCGGTCCGGAAAAATATTTGCAT
CTGATGGGACTGGACAAGAAAGTACAAGGCGGGAAAATGCGTTTCATACTGCTCGAGAATATCGGTCGGGCGACGGTGCA
CGCGGACGTGCCGGCTGCGATACTGACCGAAGTTCTGACGGAATGCACGGCTGATGCATGA

Upstream 100 bases:

>100_bases
CAAAGCTTAGTGATAAGTTGTCTGGGTTATCCAAAAGAACCGCCTGCACGCTGTTTAGCGAAGCTTTCAGGCAGATCGCA
CCTCCTTTCCCATCGCAATA

Downstream 100 bases:

>100_bases
GCTGGCGGCCTACGCGGTATCAACTGCCAACTCCCGGGGGCGCCGCATTGCGGAAGAAGCCTCTCCCGGTCGCACGCCTT
TTCAGCGCGATCGCGATCGC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
METVTVNLVSTPAQRGYPIHIGANILTQPELILDYLDQKRVAIVTNTTVGPLYLEKFRADLSVHGMVSVPIVLPDGEEYK
NWETLNLIFDALLTHRCERNTPLIALGGGVVGDLTGFAAATYLRGVPFIQVPTTLLAQVDSSVGGKTGINHPLGKNMIGA
FYQPQAVVADTSTLDTLPDRELRAGIAEVIKYGLIRDPAFFDWIESHIELLLRRDNSILTDAIKRSCQHKAEVVEEDERE
SGMRALLNLGHTFGHAIENAMGYGNWLHGEAVAAGTMLAAEVSRRMGMIGEEDVDRVRNLYVKTGLPVIAPNLGPEKYLH
LMGLDKKVQGGKMRFILLENIGRATVHADVPAAILTEVLTECTADA

Sequences:

>Translated_366_residues
METVTVNLVSTPAQRGYPIHIGANILTQPELILDYLDQKRVAIVTNTTVGPLYLEKFRADLSVHGMVSVPIVLPDGEEYK
NWETLNLIFDALLTHRCERNTPLIALGGGVVGDLTGFAAATYLRGVPFIQVPTTLLAQVDSSVGGKTGINHPLGKNMIGA
FYQPQAVVADTSTLDTLPDRELRAGIAEVIKYGLIRDPAFFDWIESHIELLLRRDNSILTDAIKRSCQHKAEVVEEDERE
SGMRALLNLGHTFGHAIENAMGYGNWLHGEAVAAGTMLAAEVSRRMGMIGEEDVDRVRNLYVKTGLPVIAPNLGPEKYLH
LMGLDKKVQGGKMRFILLENIGRATVHADVPAAILTEVLTECTADA
>Mature_366_residues
METVTVNLVSTPAQRGYPIHIGANILTQPELILDYLDQKRVAIVTNTTVGPLYLEKFRADLSVHGMVSVPIVLPDGEEYK
NWETLNLIFDALLTHRCERNTPLIALGGGVVGDLTGFAAATYLRGVPFIQVPTTLLAQVDSSVGGKTGINHPLGKNMIGA
FYQPQAVVADTSTLDTLPDRELRAGIAEVIKYGLIRDPAFFDWIESHIELLLRRDNSILTDAIKRSCQHKAEVVEEDERE
SGMRALLNLGHTFGHAIENAMGYGNWLHGEAVAAGTMLAAEVSRRMGMIGEEDVDRVRNLYVKTGLPVIAPNLGPEKYLH
LMGLDKKVQGGKMRFILLENIGRATVHADVPAAILTEVLTECTADA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=365, Percent_Identity=53.1506849315069, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6320332, Length=384, Percent_Identity=38.5416666666667, Blast_Score=217, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_NITMU (Q2YB61)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_411402.1
- ProteinModelPortal:   Q2YB61
- SMR:   Q2YB61
- STRING:   Q2YB61
- GeneID:   3786165
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A0703
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- PhylomeDB:   Q2YB61
- ProtClustDB:   PRK00002
- BioCyc:   NMUL323848:NMUL_A0703-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39969; Mature: 39969

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METVTVNLVSTPAQRGYPIHIGANILTQPELILDYLDQKRVAIVTNTTVGPLYLEKFRAD
CCEEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCC
LSVHGMVSVPIVLPDGEEYKNWETLNLIFDALLTHRCERNTPLIALGGGVVGDLTGFAAA
CEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
TYLRGVPFIQVPTTLLAQVDSSVGGKTGINHPLGKNMIGAFYQPQAVVADTSTLDTLPDR
HHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCHHCCCCCH
ELRAGIAEVIKYGLIRDPAFFDWIESHIELLLRRDNSILTDAIKRSCQHKAEVVEEDERE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
SGMRALLNLGHTFGHAIENAMGYGNWLHGEAVAAGTMLAAEVSRRMGMIGEEDVDRVRNL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YVKTGLPVIAPNLGPEKYLHLMGLDKKVQGGKMRFILLENIGRATVHADVPAAILTEVLT
HHHCCCCEEECCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHH
ECTADA
HHCCCC
>Mature Secondary Structure
METVTVNLVSTPAQRGYPIHIGANILTQPELILDYLDQKRVAIVTNTTVGPLYLEKFRAD
CCEEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCC
LSVHGMVSVPIVLPDGEEYKNWETLNLIFDALLTHRCERNTPLIALGGGVVGDLTGFAAA
CEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
TYLRGVPFIQVPTTLLAQVDSSVGGKTGINHPLGKNMIGAFYQPQAVVADTSTLDTLPDR
HHHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCHHCCCCCH
ELRAGIAEVIKYGLIRDPAFFDWIESHIELLLRRDNSILTDAIKRSCQHKAEVVEEDERE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
SGMRALLNLGHTFGHAIENAMGYGNWLHGEAVAAGTMLAAEVSRRMGMIGEEDVDRVRNL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
YVKTGLPVIAPNLGPEKYLHLMGLDKKVQGGKMRFILLENIGRATVHADVPAAILTEVLT
HHHCCCCEEECCCCHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHH
ECTADA
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA